Vecuronium bromide is a competitiveAchR inhibitor and binds to cholinergic receptors at neuromuscular junctions, used as an aminosteroidal neuromuscular blocking agent.
Vecuronium Bromide is an aminosteriodal competitive neuromuscular blocking agent. It is used in general anesthesia as it causes muscle relaxation facilitating endotracheal intubation and to aid controlled ventilation. The pH 6 was found to be suitable for determination of VEC (Vecuronium Bromide) (pka = 8.97)[3]. Vecuronium (Bromide) produced a potent inhibition on the adult muscle-type acetylcholine receptor (IC50=8.7 nM) by competitive antagonism. Furthermore, at increasing acetylcholine concentrations, there was a significant decrease in the inhibition of the acetylcholine currents produced by 10 nM vecuronium[4].
United States, Texas
... 展开 >>
McGovern Medical School part of UT Health
Recruiting
Houston, Texas, United States, 77030
Contact: Sunil Sheth, MD 713-500-7897 sunil.a.sheth@uth.tmc.edu
Contact: Aditya Sanzgiri, MBBS MPH 713-704-7263 Aditya.A.Sanzgiri@uth.tmc.edu
Principal Investigator: Sunil A Sheth, MD 收起 <<
Korea, Republic of
... 展开 >>
Severance hospital
Recruiting
Seoul, Korea, Republic of, 120-752
Contact: Young jun Oh, MD 82-2-2228-2420 yjoh@yuhs.ac
Sub-Investigator: Jin Sun Jo, MD 收起 <<
Finland
... 展开 >> Department of Anesthesiology, Intensive Care, Emergency Care and Pain Medicine, Turku University Hospital
Turku, Finland, FI-20520 收起 <<
Easy of Laryngoscopy Manipulat... 展开 >>ion
Vocal Cord Position or Movement
Patient Reaction to Intubation and Cuff Inflation
Mean Arterial Pressure
Heart Rate 收起 <<
Not Applicable
Completed
-
Korea, Republic of
... 展开 >>
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, Korea, Republic of, 463-707 收起 <<
Coronary Artery Bypass Graft R... 展开 >>edo
General Anesthetic Drug Adverse Reaction 收起 <<
Phase 4
Unknown
June 2017
China, Hubei
... 展开 >> Dept. of Anesthesiolgy, Tongji hospital of Tongji Medical College, Huazhong University of Science and Technology
Recruiting
Wuhan, Hubei, China, 430030
Contact: Ailin Luo, Doctor 86-13507122565 alluo@tjmu.tjh.edu.cn 收起 <<
India
... 展开 >> Justice K. S. Hegde Hospital, K S Hegde Medical Academy, Nitte University
Recruiting
Mangalore, Dakshina Kannada, India, 575018
Contact: Sara Jaison, MBBS 09900632065 sara_jaison@yahoo.co.in
Contact: Sripada G Mehandale, MBBS, MD 09448384310 dr_sgmehandale@rediffmail.com
Principal Investigator: Sara Jaison, MBBS 收起 <<
United States, California
... 展开 >>
Childrens Hospital Los Angeles ( Site 0030)
Recruiting
Los Angeles, California, United States, 90027
Contact: Study Coordinator 323-361-8649
Lucille Packard Children's Hospital ( Site 0006)
Completed
Palo Alto, California, United States, 94304
United States, District of Columbia
Children's National Medical Center ( Site 0008)
Recruiting
Washington, District of Columbia, United States, 20010
Contact: Study Coordinator 202-476-2025
United States, Michigan
C.S. Mott Children's Hospital/ University of Michigan Medical center ( Site 0014)
Recruiting
Ann Arbor, Michigan, United States, 48109-4245
Contact: Study Coordinator 734-763-2435
United States, New Jersey
Saint Peter's University Hospital [New Brunswick, NJ] ( Site 0009)
Completed
New Brunswick, New Jersey, United States, 08901
United States, North Carolina
Duke University Medical Center ( Site 0019)
Recruiting
Durham, North Carolina, United States, 27710
Contact: Study Coordinator 919-681-4877
United States, Pennsylvania
Children's Hospital of Pittsburgh of UPMC ( Site 0005)
Recruiting
Pittsburgh, Pennsylvania, United States, 15224
Contact: Study Coordinator 412-692-6390 收起 <<
Russian Federation
... 展开 >>
Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology
Moscow, Russian Federation 收起 <<
China, Beijing
... 展开 >> Chinese PLA General Hospital
Recruiting
Beijing, Beijing, China, 100000
Contact: Weidong Mi, Doctor +86 13381082966 wwdd1962@yahoo.com.cn
Peking Union Medical College Hospital
Recruiting
Beijing, Beijing, China, 100000
Contact: Jing Zhao, Doctor +86 13901048114 Zhaojing1009@yahoo.com.cn
Peking University First Hospital
Recruiting
Beijing, Beijing, China, 100034
Contact: Yuan Zeng, Doctor +86 13520703600 yuan_zeng@sina.com
Principal Investigator: Yuan Zeng, Doctor
China, Guangdong
First Affiliated Hospital, Sun Yat-Sen University
Recruiting
Guangzhou, Guangdong, China, 510000
Contact: Wenqi Huang, Doctor +86 13802963182 huangwenqi86@yahoo.com.cn
The First Affiliated Hospital of Guangzhou Medical University
Recruiting
Guangzhou, Guangdong, China, 510000
Contact: Qinglong Dong, Doctor 13602837397 qldong@163.net
Zhujiang Hospital Southern Medical University
Recruiting
Guangzhou, Guangdong, China, 510000
Contact: Shiyuan Xu, Doctor +86 13609727860 xushiyuan355@yahoo.com.cn
China, Hebei
Hebei Medical University Fourth Hospital
Recruiting
Shijiazhuang, Hebei, China, 050000
Contact: Zixian Song, Doctor +86 13400312688 zixiansong@126.com
China, Henan
The First Affiliated Hospital of Zhengzhou University
Recruiting
Zhengzhou, Henan, China, 450000
Contact: Wei Zhang, Doctor +86 13673996966 Zhangw571012@126.com
China, Hubei
Tongji Hospital, Tongji Medical College of HUST
Recruiting
Wuhan, Hubei, China, 430000
Contact: Ailin Luo, Doctor +86 13507122565 ailinluo@yahoo.cn
Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Recruiting
Wuhan, Hubei, China, 430000
Contact: Qingping Wu, Doctor +86 13971605283 Wqp1968@163.com
China, Hunan
The Second Xiangya Hospital of Central South University
Recruiting
Changsha, Hunan, China, 410000
Contact: Junmei Xu, Doctor +86 13975148864 13975148864@139.com
Xiangya Hospital of Central South University
Recruiting
Changsha, Hunan, China, 410000
Contact: Qulian Guo, Doctor +86 13707315866 qulianguo@hotmail.com
China, Liaoning
China Medical University Hospital
Recruiting
Shenyang, Liaoning, China, 110000
Contact: Hong Ma, Doctor +86 13840366406 mahong5466@yahoo.com
China, Shanghai
Eastern Hepatobiliary Surgery Hospital
Recruiting
Shanghai, Shanghai, China, 200000
Contact: Weifeng Yu, Doctor +86 13901961704 Ywf808@yeah.net
RenJi Hospital
Recruiting
Shanghai, Shanghai, China, 200000
Contact: Xiangrui Wang, Doctor 13701901953 xiangrui68@163.com
Ruijin Hospital
Recruiting
Shanghai, Shanghai, China, 200000
Contact: Qingsheng Xue, Doctor +86 13611909814 xueqingsheng@yahoo.com.cn
Shanghai First People's Hospital
Recruiting
Shanghai, Shanghai, China, 200000
Contact: Yingtian Wang, Doctor +86 13386259639 wang_didi26@yahoo.com.cn
Shanghai Zhongshan Hospital
Recruiting
Shanghai, Shanghai, China, 200000
Contact: Zhanggang Xue, Doctor 13601914601 xuezgang@yahoo.com.cn
China, Sichuan
West China Hospital, Sichuan University
Recruiting
Chengdu, Sichuan, China, 610000
Contact: Bin Liu, Doctor +86 13808186401 benbinliu@yahoo.com.cn
China, Tianjin
Tianjin Medical University General Hospital
Recruiting
Tianjin, Tianjin, China, 300000
Contact: Guolin Wang, Doctor +86 15822855556 wang_guolin@hotmail.com
China, Xinjiang
The First Teaching Hospital of Xinjiang Medical University
Withdrawn
Urumchi, Xinjiang, China, 830000
China, Zhejiang
The First Affiliated Hospital Of College of Medicine, Zhejiang University
Recruiting
Hangzhou, Zhejiang, China, 310000
Contact: Shenmei Zhu, Doctor 13857169801 smzhu20088@yahoo.com.cn 收起 <<
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