石杉碱甲 /(-)-Huperzine A {[allProObj[0].p_purity_real_show]}
货号：A161814同义名：
石杉碱
/ Hup A;(−)-Selagine
Huperzine A is a naturally occurring sesquiterpene alkaloidAChE inhibitor.
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Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, reversible, selective inhibitor of acetylcholinesterase (AChE) used in China for the treatment of Alzheimer's disease[3]. Inhibition of fetal bovine serum acetylcholinesterase by (-)-Huperzine A was 35-fold more potent than (+)-Huperzine A, with KI values of 6.2 nM and 210 nM, respectively. In addition, (-)-Huperzine A was 88-fold more potent in inhibiting Torpedo acetylcholinesterase than (+)-Huperzine A, with KI values of 0.25 mM and 22 mM, respectively[4]. Huperzine A treatment significantly decreased the level of intracellular Aβ42 and ameliorated oligomeric Aβ42 induced mitochondrial dysfunctions in primary cortical neurons[5].
30% propylene glycol+5% Tween 80+65% water 30 mg/mLsuspension
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Tags:
(-)-Huperzine A | Hup A;(−)-Selagine;(-)-Selagine.;Selagine;(−)-Huperzine A;Huperzine A | 石杉碱 | AChE | AmBeed-信号通路专用抑制剂
| (-)-Huperzine A 纯度/质量文件
| (-)-Huperzine A 生物活性
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| (-)-Huperzine A 技术信息
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