绿原酸 /Chlorogenic acid
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货号：A163338
同义名：
3-O-Caffeoylquinic acid;Heriguard
Chlorogenic ac id是金银花中的一种主要酚类 化合物，口服活性化合物，具有抗氧化、抗菌、护肝、护心、抗炎 、解热、神经保护、抗肥胖、抗病毒 、抗微生物和抗高血压等特性。
Chlorogenic acid 化学结构
Chlorogenic acid 3D分子结构
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Chlorogenic acid 纯度/质量文件 产品仅供科研
货号：A163338
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Chlorogenic acid 质控信息
Chlorogenic acid 生物活性
描述
Chlorogenic acid is a phenolic compound from the hydroxycinnamic acid family and possesses many health-promoting properties such as anti-oxidant, anti-inflammatory, antilipidemic, antidiabetic, and antihypertensive activities.in vivo , Mice were treated with vehicle, 250 mg/kg BW oral gavage metformin or 250 mg/kg BW chlorogenic acid intraperitoneally daily for 2 weeks.Chlorogenic acid inhibited hepatic glucose-6-phosphatase expression and activity, decreased hepatic steatosis, improved lipid profiles and skeletal muscle glucose uptake[3] [4]
Chlorogenic acid 参考文献
[1] Guo YJ, Luo T, et al. Involvement of TLR2 and TLR9 in the anti-inflammatory effects of chlorogenic acid in HSV-1-infected microglia. Life Sci. 2015 Apr 15;127:12-8.
[2] Chen WP, Wu LD. Chlorogenic acid suppresses interleukin-1β-induced inflammatory mediators in human chondrocytes. Int J Clin Exp Pathol. 2014 Dec 1;7(12):8797-801.
[3] Santana-Gálvez J, Cisneros-Zevallos L, Jacobo-Velázquez DA. Chlorogenic Acid: Recent Advances on Its Dual Role as a Food Additive and a Nutraceutical against Metabolic Syndrome. Molecules. 2017 Feb 26;22(3):358. doi: 10.3390/molecules22030358. PMID: 28245635; PMCID: PMC6155416.
[4] Han X, Zhang Y, Guo J, You Y, Zhan J, Huang W. Chlorogenic Acid Stimulates the Thermogenesis of Brown Adipocytes by Promoting the Uptake of Glucose and the Function of Mitochondria. J Food Sci. 2019 Dec;84(12):3815-3824. doi: 10.1111/1750-3841.14838. Epub 2019 Nov 21. PMID: 31750946.
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Chlorogenic acid 实验方案
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1mg
5mg
10mg
1 mM
5 mM
10 mM
2.82mL
0.56mL
0.28mL
14.11mL
2.82mL
1.41mL
28.22mL
5.64mL
2.82mL
Chlorogenic acid 技术信息
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