Ipratropium bromide | Sch 1000 | mAChR Antagonist | AmBeed-信号通路专用抑制剂

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异丙托溴铵 /Ipratropium bromide {[allProObj[0].p_purity_real_show]}

货号：A163960 同义名： Sch 1000;Ipratropium (bromide)

Ipratropium bromide is a synthetic derivative of the alkaloid atropine anticholinergic properties with anticholinergic properties.

Ipratropium bromide 化学结构
CAS号：22254-24-6

Ipratropium bromide 3D分子结构
CAS号：22254-24-6

规格	价格	会员价	库存	数量
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Ipratropium bromide 纯度/质量文件产品仅供科研

货号：A163960 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

全球学术期刊中引用的产品: • Nat. Biomed. Eng., 2024, 8, 1412-1424. Ambeed. [ A538667 , A631746 ]; • JMC, 2024. Ambeed. [ A833302 , A475501 , A341986 , A356070 ]; • BMC Cancer, 2024, 24(1): 1415. Ambeed. [ A809692 , A209020 ]; • J. Am. Soc. Mass Spectrom., 2024, 35(12): 3192-3202. Ambeed. [ A166127 , A902473 , A753371 , A961334 , A292945 , A230770 , A300620 , A1114580 , A1159765 , A206238 ]; • PloS One, 2024, 19(11): e0308060. Ambeed. [ A302917 ]; 更多 >

AChR 亚型比较

产品名称	AChE ↓ ↑	AChR ↓ ↑	mAChR ↓ ↑	nAChR ↓ ↑	其他靶点	纯度
Donepezil	+++ hAChE, IC50: 11.6 nM bAChE, IC50: 8.12 nM					98%
Loganin	++ AChE, IC50: 3.95 μM					99%+
topride HCl	++ AChE, IC50: 2.04 μM					98%
Dehydroevodiamine HCl	✔					99%+
Jatrorrhizine	++ AChE, IC50: 872 nM					99%+
Palmatine	++ AChE, IC50: 0.51 μM					98%
(-)-Huperzine A	++++ AChE (G4 form), Ki: 7 nM					98%
Galanthamine HBr	++ AChE, IC50: 0.35 μM					98%
Trospium chloride		✔				99%
Tiotropium Bromide Monohydrate		✔				98+%
Gallamine Triethiodide		+ AChR, IC50: 68.0 μM				98%
Hexamethonium Bromide		✔				99%
Pancuronium dibromide		✔				98%
Neostigmine bromide		✔				98%
Orphenadrine citrate		✔				98%
Oxybutynin		✔				98%
Irsogladine		✔			PDE	98%
Pyridostigmine bromide		✔				99+%
Rivastigmine		+ AChR, IC50: 5.5 μM				98%
Paroxetine hydrochloride		✔				97%
Rocuronium Bromide		✔				98%
Tropicamide			+++ M4 mAChR, IC50: 8 nM			98%
Diphenmanil methylsulfate			✔			98%
Umeclidinium bromide			✔			95%
Otilonium bromide			✔			98%
Flavoxate HCl			+ mAChR, IC50: 12.2 μM			98%
Ipratropium bromide			✔			98%
Diphenidol HCl			✔			98%
Darifenacin hydrobromide			++++ M3 mAChR, pKi: 8.9			98%
Aclidinium Bromide			++++ M4 mAChR, Ki: 0.21 nM M2 mAChR, Ki: 0.1 nM			98%
Oxybutynin chloride			✔			99%
Pentoxyverine citrate			✔			98%
Solifenacin			✔			98%
Catharanthine				✔		98%
Benzethonium chloride				+++ α4β2 nAChRs, IC50: 49 nM α7 nAChRs, IC50: 122 nM		99+%
Vinblastine sulfate				+ nAChR, IC50: 8.9 μM		99%
PNU-120596				++ α7 nAChR, EC50: 216 nM		99+%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

Ipratropium bromide 生物活性

靶点

mAChR

描述

Ipratropium Bromide, as short‐acting anticholinergic, is indicated for the maintenance treatment of bronchospasm associated with COPD (chronic obstructive pulmonary disease), including chronic bronchitis and emphysema^[3]. Both IB (Ipratropium Bromide) and AS (Albuterol Sulfate) elicit significant bronchodilation, although the magnitude of the bronchodilator response is greater following IB^[4]. Moreover, routine nebulized ipratropium bromide premedication for bronchoscopy could be useful and beneficial^[5].

Ipratropium bromide 临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT03405090	Chronic Obstructive Pulmonary ... 展开 >>Disease 收起 <<	Phase 4	Recruiting	August 2019	Canada, Ontario ... 展开 >> Respiratory Investigation Unit Recruiting Kingston, Ontario, Canada, K7L 2V7 Contact: Megha Ibrahim Masthan, MSc 613-549-6666 ext 4314 mim5@queensu.ca Contact: Sandra Vincent 613-549-6666 ext 4890 vincents@queensu.ca Principal Investigator: Denis E O'Donnell, MD, FRCPC 收起 <<
NCT00498251	Lung Injury, Acute ... 展开 >> Thoracotomy Anesthesia Intensive Care, Surgical Extravascular Lung Water 收起 <<	Not Applicable	Completed	-	Switzerland ... 展开 >> University Hospital of Geneva Geneva, Switzerland, CH-1211 收起 <<
NCT01395875	-		Completed	-	-

Ipratropium bromide 参考文献

[1]Zhang W, et al. Eur J Pharmacol,?010, 647(1-3), 178-187.

[2]Shaik N, et al. Cell Physiol Biochem,?012, 30(6), 1517-1525.

[3]MacGregor TR, ZuWallack R, Rubano V, Castles MA, Dewberry H, Ghafouri M, Wood CC. Efficiency of Ipratropium Bromide and Albuterol Deposition in the Lung Delivered via a Soft Mist Inhaler or Chlorofluorocarbon Metered-Dose Inhaler. Clin Transl Sci. 2016 Apr;9(2):105-13.

[4]Schilero GJ, Hobson JC, Singh K, Spungen AM, Bauman WA, Radulovic M. Bronchodilator effects of ipratropium bromide and albuterol sulfate among subjects with tetraplegia. J Spinal Cord Med. 2018 Jan;41(1):42-47.

[5]Wang F, Zheng H, Zhang Y, Zhu H, Shi J, Luo Y, Zhang X, Mao H, Herth FJF, Luo F. Nebulized Ipratropium bromide protects against tracheal and bronchial secretion during bronchoscopy: A randomized controlled trial. Medicine (Baltimore). 2019 Nov;98(47):e17942.

Ipratropium bromide 实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

2.43mL

0.49mL

0.24mL

12.13mL

2.43mL

1.21mL

24.25mL

4.85mL

2.43mL

Ipratropium bromide 技术信息

CAS号	22254-24-6
分子式	C₂₀H₃₀BrNO₃
分子量	412.361

别名	Sch 1000;Ipratropium (bromide)
运输	蓝冰

存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Inert atmosphere,Room Temperature

溶解度

DMSO: 35 mg/mL(84.88 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H₂O: 100 mg/mL(242.51 mM)，配合低频超声助溶

动物实验配方

临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT03405090	Chronic Obstructive Pulmonary ... 展开 >>Disease 收起 <<	Phase 4	Recruiting	August 2019	Canada, Ontario ... 展开 >> Respiratory Investigation Unit Recruiting Kingston, Ontario, Canada, K7L 2V7 Contact: Megha Ibrahim Masthan, MSc 613-549-6666 ext 4314 mim5@queensu.ca Contact: Sandra Vincent 613-549-6666 ext 4890 vincents@queensu.ca Principal Investigator: Denis E O'Donnell, MD, FRCPC 收起 <<
NCT00498251	Lung Injury, Acute ... 展开 >> Thoracotomy Anesthesia Intensive Care, Surgical Extravascular Lung Water 收起 <<	Not Applicable	Completed	-	Switzerland ... 展开 >> University Hospital of Geneva Geneva, Switzerland, CH-1211 收起 <<
NCT01395875	-		Completed	-	-
NCT02176200	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 3	Terminated	-	-
NCT00388882	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 4	Completed	-	-
NCT03064113	Chronic Obstructive Pulmonary ... 展开 >>Disease, COPD 收起 <<	Phase 2	Completed	-	New Zealand ... 展开 >> P3 Research Wellington, New Zealand, 6021 收起 <<
NCT01337336	-		Completed	-	-
NCT00000568	Lung Diseases ... 展开 >> Lung Diseases, Obstructive Chronic Obstructive Pulmonary Disease 收起 <<	Phase 3	Completed	-	-
NCT01337336	-		Completed	-	-
NCT02173678	Healthy	Phase 1	Completed	-	-
NCT02686086	Chronic Obstructive Pulmonary ... 展开 >>Disease (COPD) 收起 <<	Not Applicable	Unknown	July 2016	Ireland ... 展开 >> Beaumont Hospital Recruiting Dublin, Ireland Contact: Breda Cushen, MB BCh BAO +35318093736 bredacushen@rcsi.ie 收起 <<
NCT00522444	Asthma	Phase 3	Terminated(institution in Cana... 展开 >>da is conducting a similar clinical trial with potential of validating use.) 收起 <<	-	-
NCT01655199	Moderate Chronic Obstructive P... 展开 >>ulmonary Disease Severe Chronic Obstructive Pulmonary Disease Dyspnea 收起 <<	Not Applicable	Unknown	July 2014	Canada, Quebec ... 展开 >> Montreal Chest Institute - McGill University Recruiting Montréal, Quebec, Canada Contact: Jean Bourbeau, M.D jean.bourbeau@mcgill.ca Contact: Hélène Perrault, Ph.D helene.perrault@mcgill.ca Sub-Investigator: Jean Bourbeau, M.D Institut Universitaire de Cardiologie et de Pneumologie de Québec - Université Laval Active, not recruiting Québec, Quebec, Canada 收起 <<
NCT02584738	Asthma	Phase 4	Unknown	January 2018	Mexico ... 展开 >> Hospital General Naval de Alta Especialidad Recruiting México, Distrito Federal, Mexico, 04480 Contact: Jesús Abisai Uicab Saucedo, Pediatrician (52)5550371200 ext 5423 abisaipec@msn.com 收起 <<
NCT01360788	-		Completed	-	Canada, Quebec ... 展开 >> Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval Québec, Quebec, Canada, G1V 4G5 收起 <<
NCT00584181	-		Completed	-	United States, Texas ... 展开 >> University of Texas Medical Branch Galveston, Texas, United States, 77555 收起 <<
NCT02172404	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 3	Completed	-	-
NCT00904436	Dyspnea Tetra... 展开 >>plegia 收起 <<	Not Applicable	Completed	-	United States, New York ... 展开 >> VA Medical Center, Bronx Bronx, New York, United States, 10468 收起 <<
NCT02238184	-		Completed	-	-
NCT03042065	Asthma	Not Applicable	Not yet recruiting	September 2017	-
NCT01381458	-		Completed	-	-
NCT01696214	-		Completed	-	-
NCT01696214	Asthma	Phase 4	Completed	-	United States, California ... 展开 >> Airway Research & Clinical Trials Center San Diego, California, United States, 92103 收起 <<
NCT02458482	Asthma	Not Applicable	Recruiting	June 2023	United States, Tennessee ... 展开 >> Vanderbilt University Medical Center Monroe Carell Jr. Childrens Hospital Pediatric Emergency Department Recruiting Nashville, Tennessee, United States, 37232 Contact: Evan H Allie, MD 423-943-6596 evan.h.allie@vanderbilt.edu Contact: Donald H Arnold, MS, MD 615-936-4498 don.arnold@vanderbilt.edu Sub-Investigator: John Fischer, RRT, EMT-IV Principal Investigator: Evan H Allie, MD Sub-Investigator: Donald H Arnold, BS, MD Sub-Investigator: Jeff Steinbarge, RRT 收起 <<
NCT01969539	-		Terminated	-	-
NCT03271905	COPD Asthma	Not Applicable	Recruiting	December 10, 2019	Brazil ... 展开 >> Cibelle Andrade Lima Recruiting Recife, Pernambuco, Brazil, 50610060 Contact: cibelle A lima, M.D 8199752532 cibellea@yahoo.com 收起 <<
NCT02207452	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 1	Completed	-	United Kingdom ... 展开 >> GSK Investigational Site Sheffield, United Kingdom, S10 2JF 收起 <<
NCT02315144	Chronic Obstructive Pulmonary ... 展开 >>Disease 收起 <<	Phase 1	Terminated(Business decision)	-	United States, Oregon ... 展开 >> Teva Investigational Site 13038 Medford, Oregon, United States United States, South Carolina Teva Investigational Site 13039 Spartanburg, South Carolina, United States Australia Teva Investigational Site 78992 Clayton, Australia Teva Investigational Site 78993 Daws Park, Australia Teva Investigational Site 78991 Melbourne, Australia New Zealand Teva Investigational Site 79041 Auckland, New Zealand Teva Investigational Site 79040 Christchurch, New Zealand 收起 <<
NCT01524198	Status Asthmaticus	Phase 2 Phase 3	Completed	-	Saudi Arabia ... 展开 >> King Fahad Medical City Riyadh, Saudi Arabia, 11525 收起 <<
NCT01969539	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 4	Terminated	-	United States, Connecticut ... 展开 >> 1012.65.00001 Boehringer Ingelheim Investigational Site Danbury, Connecticut, United States United States, Texas 1012.65.00002 Boehringer Ingelheim Investigational Site Fort Worth, Texas, United States 收起 <<
NCT01524198	-		Completed	-	-
NCT00400153	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 3	Completed	-	-
NCT01331694	-		Completed	-	-
NCT02296047	Chronic Obstructive Pulmonary ... 展开 >>Disease (COPD) 收起 <<	Not Applicable	Completed	-	China, Guangdong ... 展开 >> Zhujiang Hospital,Southern Medical Universtiy Guangzhou, Guangdong, China, 510282 收起 <<
NCT02315131	Chronic Obstructive Pulmonary ... 展开 >>Disease (COPD 收起 <<	Phase 1	Terminated(Business decision)	-	United States, Missouri ... 展开 >> Teva Investigational Site 13033 Saint Louis, Missouri, United States United States, North Carolina Teva Investigational Site 13034 Raleigh, North Carolina, United States Australia Teva Investigational Site 78984 Adelaide, Australia Teva Investigational Site 78985 Nedlands, Australia New Zealand Teva Investigational Site 79037 Auckland, New Zealand Teva Investigational Site 79036 Hamilton, New Zealand Teva Investigational Site 79034 Wellington, New Zealand 收起 <<
NCT00460577	Acute Bronchial Obstruction, A... 展开 >>sthma 收起 <<	Phase 4	Completed	-	Venezuela ... 展开 >> Novartis Investigator site - five sites in Caracas Caracas, Venezuela Novartis Investigator Site Maracaibo, Venezuela 收起 <<
NCT01331694	-		Completed	-	-
NCT00400153	-		Completed	-	-
NCT00460577	-		Completed	-	-
NCT02182505	Asthma	Phase 3	Completed	-	-
NCT00462540	Chronic Obstructive Pulmonary ... 展开 >>Disease 收起 <<	Phase 3	Completed	-	United States, California ... 展开 >> Research Site San Diego, California, United States, 92120 United States, Colorado Research Site Denver, Colorado, United States, 80206 Research Site Wheat Ridge, Colorado, United States, 80033 United States, Florida Research Site Panama City, Florida, United States, 32405 Research Site Pensacola, Florida, United States, 32504 United States, Idaho Research Site Coeur d'Alene, Idaho, United States, 83814 United States, Louisiana Research Site Sunset, Louisiana, United States, 70584 United States, North Carolina Research Site Charlotte, North Carolina, United States, 28207 United States, Oregon Research Site Portland, Oregon, United States, 97213 United States, South Carolina Research Site Gaffney, South Carolina, United States, 29340 Research Site Spartanburg, South Carolina, United States, 29303 United States, Tennessee Research Site Johnson City, Tennessee, United States, 37601 United States, Texas Research Site San Antonio, Texas, United States, 78205 United States, Washington Research Site Spokane, Washington, United States, 99204 United States, West Virginia Research Site Morgantown, West Virginia, United States, 26505 收起 <<
NCT03738917	Acute Bronchitis	Phase 4	Not yet recruiting	December 31, 2020	Spain ... 展开 >> Nova Lloreda Health Center Not yet recruiting Badalona, Catalonia, Spain, 08910 Contact: Maria Vila Royo, MD 0034934603900 mvila.cp.ics@gencat.cat Martí i Julià Health Center Not yet recruiting Badalona, Catalonia, Spain, 08911 Contact: Miquel Morales Guerra 0034931671840 mmorales.cp.ics@gencat.cat Balaguer Health Center Not yet recruiting Balaguer, Catalonia, Spain, 25600 Contact: Jesus Pujol, MD PhD 0034973447714 dr.indomable@gmail.com Via Roma Health Centre Not yet recruiting Barcelona, Catalonia, Spain, 08015 Contact: Carl Llor, MD PhD 693696644 ext 693696644 carles.llor@gmail.com La Marina Health Center Not yet recruiting Barcelona, Catalonia, Spain, 08027 Contact: Josep M. Cots, MD PhD 0034601381364 23465jcy@comb.cat Contact: Carolina A Bayona, MD PhD 0034680612162 31217cbf@comb.cat CAP Passeig Maragall (EAP Camp de l'Arpa) Not yet recruiting Barcelona, Catalonia, Spain, 08041 Contact: Maite Tierno Ortega, MD 934462950 mtierno@gencat.cat Cornellà - La Gavarra Health Center Not yet recruiting Cornellà De Llobregat, Catalonia, Spain, 08940 Contact: Silvia Cobo Guerrero 0034933768250 scobo.cp.ics@gencat.cat Pineda de Mar Health Center Not yet recruiting Pineda De Mar, Catalonia, Spain, 08397 Contact: Esperança Almerich Latorre, MD 0034937671560 ealmerich.bnm.ics@gencat.cat Ca n'OriacHealth Center Not yet recruiting Sabadell, Catalonia, Spain, 08027 Contact: Olga Bigas Aguilera, MD 937233713 obigas.bcn.ics@gencat.cat Molí Nou Health Center Not yet recruiting Sant Boi De Llobregat, Catalonia, Spain, 08830 Contact: Carles Alvarado Montesdeoca, MD 0034936543300 calvarado.cp.ics@gencat.cat Singuerlin Health Center Not yet recruiting Santa Coloma De Gramenet, Catalonia, Spain, 08924 Contact: José Manuel Escudero Ibáñez, MD 0034934685800 jmescudero.bnm.ics@gencat.cat CAP Jaume I Not yet recruiting Tarragona, Catalonia, Spain, 43005 Contact: Ana Moragas, MD PhD 0034600072170 anamaria.moragas@urv.cat Contact: Silvia Hernandez, MD PhD 607811649 silviaha@comt.es 收起 <<
NCT02173782	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 3	Completed	-	-
NCT02103374	Severe Chronic Obstructive Pul... 展开 >>monary Disease 收起 <<	Phase 4	Completed	-	France ... 展开 >> Service de Pneumologie Amiens, France, 80054 Service de Pneumologie Angers, France, 49033 Service de Pneumologie Brest, France, 29609 Service de Pneumologie Grenoble, France, 38043 Service de Pneumologie Limoges, France, 87042 Service de Pneumologie Nancy, France, 54511 Service de Pneumologie Nantes, France, 44093 Service de Pneumologie Orléans, France, 45067 Service de Pneumologie Paris, France, 75004 Service de Pneumologie Poitiers, France, 86000 Service de Pneumologie Reims, France, 51100 Service de Pneumologie Rouen, France, 76031 Service de Pneumologie Tours, France, 37044 收起 <<
NCT02182479	Asthma	Phase 3	Completed	-	-
NCT01415518	Chronic Obstructive Pulmonary ... 展开 >>Disease (COPD) 收起 <<	Phase 4	Completed	-	China, Beijing ... 展开 >> Research Site Beijing, Beijing, China China, Guangdong Research Site Foshan, Guangdong, China Research Site Guangzhou, Guangdong, China Research Site Zhongshan, Guangdong, China China, Hainan Research Site Haikou, Hainan, China China, Hebei Research Site Shijiazhuang, Hebei, China Research Site Tangshan, Hebei, China China, Henan Research Site Zhengzhou, Henan, China China, Hubei Research Site Wuhan, Hubei, China China, Hunan Research Site Changsha, Hunan, China China, Jiangsu Research Site Nanjing, Jiangsu, China China, Jilin Research Site Changchun, Jilin, China China, Liaoning Research Site Shenyang, Liaoning, China China, Shandong Research Site Qingdao, Shandong, China China, Shanghai Research Site Shanghai, Shanghai, China China, Tianjin Research Site Tianjin, Tianjin, China China Research Site Chengdu, China Research Site Chongqin, China Research Site Da Lian, China Research Site Ha'er Bing, China Research Site Huhehaote, China 收起 <<
NCT03071731	Chronic Obstructive Pulmonary ... 展开 >>Disease 收起 <<	Not Applicable	Recruiting	June 15, 2019	Canada, Quebec ... 展开 >> Centre de recherche-Institut Universitaire de Cardiologie et Pneumologie de Québec Recruiting Quebec City, Quebec, Canada, G1V4G5 Contact: Kim-Ly Bui, M.pht 418-656-8711 ext 2713 kim-ly.bui@criucpq.ulaval.ca Contact: Didier Saey, Ph.D. 418-656-8711 ext 2614 didier.saey@rea.ulaval.ca 收起 <<
NCT02542254	Chronic Obstructive Pulmonary ... 展开 >>Disease 收起 <<	Phase 2	Completed	-	United Kingdom ... 展开 >> Medicines Evaluation Unit Manchester, United Kingdom 收起 <<
NCT02182713	Asthma	Phase 4	Completed	-	-
NCT00180843	Chronic Obstructive Pulmonary ... 展开 >>Disease 收起 <<	Not Applicable	Terminated(lack of resources r... 展开 >>esearch fellow left) 收起 <<	-	United Kingdom ... 展开 >> Imperial College Hammersmith Campus London, United Kingdom, W12 0HS 收起 <<
NCT01987219	Familial Dysautonomia	Phase 3	Completed	-	United States, New York ... 展开 >> NYU Medical Center New York, New York, United States, 10016 收起 <<
NCT01253473	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 4	Completed	-	United States, Alabama ... 展开 >> University of Alabama Birmingham Medical Center Birmingham, Alabama, United States, 35294 United States, California Harbor UCLA Medical Center Torrance, California, United States, 90502 United States, Colorado National Jewish Health Denver, Colorado, United States, 80206 United States, Iowa University of Iowa Iowa City, Iowa, United States, 52242 United States, Massachusetts Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 Reliant Medical Group Worcester, Massachusetts, United States, 01608 United States, Pennsylvania Temple University Medical Center Philadelphia, Pennsylvania, United States, 19140 收起 <<
NCT01415518	-		Completed	-	-
NCT01987219	-		Completed	-	-
NCT01019694	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 3	Completed	-	-
NCT00335621	Chronic Obstructive Pulmonary ... 展开 >>Disease 收起 <<	Phase 4	Withdrawn(Study terminated pri... 展开 >>or to recruitment - recruitment proved impossible) 收起 <<	-	United Kingdom ... 展开 >> Department of Respiratory Medicine, Glasgow Royal Infirmary Glasgow, United Kingdom, G4 0SF 收起 <<
NCT01243788	Chronic Obstructive Pulmonary ... 展开 >>Disease (COPD) 收起 <<	Phase 4	Unknown	October 2011	China, Anhui ... 展开 >> Affiliated Hospital of Anhui Medical College Recruiting Hefei, Anhui, China, 230022 Contact: Gengyun G Sun, Doctor 8613966673211 sungengyun@tom.com China, Beijing Beijing Chaoyang Hospital Recruiting Beijing, Beijing, China, 100020 Contact: Yingxiang Y Lin, Master 8613611370119 linyx666@yahoo.com.cn Peking University Third Hospital Recruiting Beijing, Beijing, China, 100191 Contact: Bei B HE, Bachlor 8613910125933 puh3_hb@bjmu.edu.cn China, Guangdong Gguang Zhou Institute of Respiratory Disease Recruiting Guangzhou, Guangdong, China, 510120 Contact: Jingfang J Ma, Master 8620-83062880 majf1216@163.com China, Henan Henan Province Hospital Recruiting Zhengzhou, Henan, China, 450003 Contact: Lijun L Ma, Bachlor 8613837115111 malijun0401@163.com China, Jiangsu Jiangsu Province Hospital Recruiting Nanjing, Jiangsu, China, 210004 Contact: Mao M Huang, Doctor 8613813886116 Hm6114@126.com Wuxi People's Hospital, Recruiting Wuxi, Jiangsu, China, 214002 Contact: Fuxing F Hui, Bachlor 8613358111977 HFX110705@sina.com China, Liaoning Shenyang Military General Hospital Recruiting Shenyang, Liaoning, China, 110016 Contact: Ping P Chen, Doctor 8613309887193 HXNK2004@126.com China, Shanghai Zhongshan Hospital Recruiting Shanghai, Shanghai, China, 200032 Contact: Yutong Y GU, doctor 8621-64041990 ext 2425 gu.yutong@zs-hospital.sh.cn China, Sichuan West China Hospital of Sichuan Recruiting Chendu, Sichuan, China, 610041 Contact: Fuqiang F Wen, Doctor 8613628040336 wenfuqiang@126.com Chongqing Xinqiao Hospital Recruiting Chongqing, Sichuan, China, 430007 Contact: Changzheng C Wang, Doctor 8613983815706 czwang@netease.com 收起 <<
NCT00393367	Asthma Acute ... 展开 >>Asthma Reactive Airway Exacerbation 收起 <<	Phase 4	Completed	-	United States, Pennsylvania ... 展开 >> Children's Hospital of Philadelphia Emergency Department Philadelphia, Pennsylvania, United States, 19104 收起 <<
NCT00239473	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 3	Completed	-	Germany ... 展开 >> Boehringer Ingelheim Investigational Site Berlin, Germany MEDARS GmbH Berlin, Germany Boehringer Ingelheim Investigational Site Bonn, Germany Boehringer Ingelheim Investigational Site Frankfurt/Main, Germany Inamed Research GmbH & Co. KG Gauting, Germany Pneumologisches Forschungsinstitut GmbH Großhansdorf, Germany Pneumologisches Forschungsinstitut GmbH am Krankenhaus Hamburg, Germany Boehringer Ingelheim Investigational Site Hannover, Germany Universitätsklinikum Schleswig-Holstein Kiel, Germany ClinPharm International GmbH & Co. KG Leipzig, Germany Neurologische Klinik der Otto-von-Guericke-Universität Magdeburg, Germany Johannes-Gutenberg-Universität Mainz Mainz, Germany Boehringer Ingelheim Investigational Site Minden, Germany Medizinische Klinik III Moers, Germany Boehringer Ingelheim Investigational Site München, Germany Abt. Lungen- und Bronchialheilkunde Schmallenberg, Germany Boehringer Ingelheim Investigational Site Steinfurt, Germany Italy Ospedale Generale Provinciale Mazzoni Ascoli Piceno, Italy Dip. di Medicina Interna e Medicina Specialistica Catania, Italy U. O. di Fisiopatologia Respiratoria Ferrara, Italy Ospedale S. Martino Genova, Italy U. O. di Pneumologia e Servizio di Fisiopatologia Resp. Milano, Italy IRCCS Policlinico San Matteo Pavia, Italy U. O. C di Pneumologia Roma, Italy Ospedale Silvestrini San Sisto (pg), Italy U. O. di Pneumologia Trieste, Italy South Africa Hydromed Hospital Bloemfontein, South Africa UCT Lung Institute Cape Town, South Africa 1 Military Hospital Pretoria, South Africa Tygerberg Hospital Tygerberg, South Africa Switzerland Universitätskliniken Basel Basel, Switzerland Ospedale San Giovanni Bellinzona, Switzerland Boehringer Ingelheim Investigational Site Davos, Switzerland Boehringer Ingelheim Investigational Site Laufen, Switzerland Boehringer Ingelheim Investigational Site Locarno, Switzerland Ospedale Regionale Lugano, Switzerland Boehringer Ingelheim Investigational Site Münchenstein, Switzerland Kantonsspital St. Gallen St. Gallen, Switzerland 收起 <<
NCT00393367	-		Completed	-	-
NCT00273962	Asthma	Phase 4	Completed	-	Philippines ... 展开 >> Jose Reyes Memorial Medical Center Manila, Philippines Philippine General Hospital Manila, Philippines Amang Rodriguez Hospital Marikina, Philippines San Juan de Dios Hospital Pasay, Philippines Rizal Provincial Hospital Pasig, Philippines East Ave Medical Center Quezon City, Philippines Philipines Heart Center Quezon City, Philippines Quirino Memorial Medical Center Quezon City, Philippines Philippine Children's Medical Center Quezon, Philippines, 1104 Quezon City General Hospital Quezon, Philippines 收起 <<
NCT01019694	-		Completed	-	-
NCT00274092	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 3	Completed	-	Taiwan ... 展开 >> Kaohsiung Veterans General Hospital Kaohsiung, Taiwan, 813 Kaohsiung Medical University Chung-Ho Memorial Hospital Kaohsiung, Taiwan Veterans General Hospital Taichung, Taiwan, 407 National Taiwan University Hospital Taipei, Taiwan, 100 Tri-Service General Hospital Taipei, Taiwan, 114 Veterans General Hospital Taipei, Taiwan, 12217 收起 <<
NCT00480194	-		Completed	-	-
NCT00807534	Chronic Obstructive Pulmonary ... 展开 >>Disease 收起 <<	Not Applicable	Completed	-	Canada, Quebec ... 展开 >> Hélène Perrault Montreal, Quebec, Canada François Maltais Quebec City, Quebec, Canada, G1V4G5 收起 <<
NCT00274066	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 3	Completed	-	Netherlands ... 展开 >> Twenteborg Ziekenhuis Almelo, Netherlands, 7609 PP Amphia Ziekenhuis Breda, Netherlands, 4819 EV Boehringer Ingelheim Investigational Site Groningen, Netherlands, 9700 RB Afdeling longziekten Winschoten, Netherlands, 9670 RA Gelre Ziekenhuizen Zutphen, Netherlands, 7207 BA 收起 <<
NCT00240435	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 3	Completed	-	-
NCT02238210	Cold	Phase 4	Completed	-	-
NCT02782052	Pulmonary Arterial Hypertensio... 展开 >>n 收起 <<	Phase 3	Active, not recruiting	February 2019	-
NCT00239434	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 3	Completed	-	China ... 展开 >> People Hospital of Beijing University Beijing, China, 100044 Peking Union Medical College Hospital Beijing, China, 100730 1st Hospital of Guangzhou Medical College Guangzhou, China, 510120 Zhongshan Hospital of Fudan University Shanghai, China, 200032 Shanghai 1st People Hospital Shanghai, China, 200080 1st Hospital of Chinese Medical University Shenyang, China, 110001 收起 <<
NCT02172443	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 3	Completed	-	-
NCT00674817	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 2	Completed	-	New Zealand ... 展开 >> GSK Investigational Site Wellington, New Zealand, 6035 Thailand GSK Investigational Site Chiangmai, Thailand, 50200 GSK Investigational Site Khon Kaen, Thailand, 40002 United Kingdom GSK Investigational Site Manchester, United Kingdom, M23 9LT 收起 <<
NCT02233881	-		Completed	-	-
NCT02238171	-		Completed	-	-
NCT00274040	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 3	Completed	-	Korea, Republic of ... 展开 >> Chungnam National University Hospital Daejeon, Korea, Republic of Jeonbuk National University Hospital Jeonju, Korea, Republic of Jeonnam National University Hospital Kwangju, Korea, Republic of Pusan University Hospital Pusan, Korea, Republic of Chung-ang University Hospital Seoul, Korea, Republic of Hanyang University Hosital Seoul, Korea, Republic of Kangnam St. Mary's Hospital Seoul, Korea, Republic of Korea University Hospital Seoul, Korea, Republic of Kyoungbuk National University Hospital Seoul, Korea, Republic of Kyunghee University Hospital Seoul, Korea, Republic of National Medical Center Seoul, Korea, Republic of Samsung Seoul Hospital Seoul, Korea, Republic of Seoul Asan Hospital Seoul, Korea, Republic of Seoul National University Hospital Seoul, Korea, Republic of Shinchon Severence Hosp (Yonsei University Hosp) Seoul, Korea, Republic of St. Paul's Hospital, Dept. of Respiratory Seoul, Korea, Republic of Youngdong Sevarence Hospital (Yonsei University Hospital) Seoul, Korea, Republic of Wonju Christian Hospital (Yonsei University Hosp) Wonju, Korea, Republic of 收起 <<
NCT02238145	-		Completed	-	-
NCT02238197	-		Completed	-	-
NCT00674817	-		Completed	-	-
NCT02238158	-		Completed	-	-
NCT02238132	-		Completed	-	-
NCT02233894	-		Completed	-	-
NCT00371527	Bronchitis	Not Applicable	Completed	-	United States, California ... 展开 >> South Sacramento Kaiser Permanente Sacramento, California, United States, 95823 收起 <<
NCT01136421	COPD Exacerbation	Phase 3	Completed	-	Tunisia ... 展开 >> University Hospital of Monastir Monastir, Monstir, Tunisia, 5000 Soudani Marghli Mahdia, Tunisia, 5100 收起 <<
NCT02236715	-		Completed	-	-
NCT02172781	Healthy	Phase 1	Completed	-	-
NCT00202176	Chronic Obstructive Pulmonary ... 展开 >>Disease (COPD) 收起 <<	Phase 4	Completed	-	Canada, Ontario ... 展开 >> Respiratory Investigation Unit Kingston, Ontario, Canada, K7L 2V7 收起 <<
NCT02576626	COPD	Phase 4	Completed	-	Netherlands ... 展开 >> UMCG Groningen, Netherlands, 9700RB 收起 <<
NCT00928746	-		Completed	-	-
NCT01350128	Chronic Obstructive Pulmonary ... 展开 >>Disease 收起 <<	Phase 2	Completed	-	United States, Florida ... 展开 >> Pearl Investigative Site Panama City, Florida, United States Pearl Investigative Site Winter Park, Florida, United States United States, New Jersey Pearl Investigative Site Cherry Hill, New Jersey, United States Pearl Investigative Site Summit, New Jersey, United States United States, North Carolina Pearl Investigative Site Charlotte, North Carolina, United States United States, Oregon Pearl Investigative Site Medford, Oregon, United States United States, Texas Pearl Investigative Site Longview, Texas, United States United States, Virginia Pearl Investigative Site Richmond, Virginia, United States 收起 <<
NCT00296946	Parkinson's Disease	Phase 2	Completed	-	Canada, Ontario ... 展开 >> Toronto Western Hospital, University Health Network Toronto, Ontario, Canada, M5T 2S8 收起 <<
NCT02172469	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 3	Completed	-	-
NCT01350128	-		Completed	-	-
NCT02182856	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 4	Completed	-	-
NCT02872597	Status Asthmaticus	Phase 1	Recruiting	September 2018	United States, Ohio ... 展开 >> Rainbow Babies and Children's Hospital (of Univ. Hospitals Case Med. Center) Recruiting Cleveland, Ohio, United States, 44106 Contact: Steven L Shein, MD 216-368-2329 steven.shein@uhhospitals.org 收起 <<
NCT02182700	Asthma	Phase 3	Terminated	-	-
NCT00928746	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 3	Completed	-	United States, Louisiana ... 展开 >> 244.2507.0107 Boehringer Ingelheim Investigational Site Lafayette, Louisiana, United States United States, South Carolina 244.2507.0106 Boehringer Ingelheim Investigational Site Easley, South Carolina, United States 244.2507.0102 Boehringer Ingelheim Investigational Site Gaffney, South Carolina, United States 244.2507.0104 Boehringer Ingelheim Investigational Site Greenville, South Carolina, United States 244.2507.0105 Boehringer Ingelheim Investigational Site Greenville, South Carolina, United States 244.2507.0103 Boehringer Ingelheim Investigational Site Spartanburg, South Carolina, United States 244.2507.0101 Boehringer Ingelheim Investigational Site Union, South Carolina, United States 收起 <<
NCT02177253	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 3	Completed	-	-
NCT01691482	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 4	Completed	-	United States, South Carolina ... 展开 >> GSK Investigational Site Spartanburg, South Carolina, United States, 29303 United Kingdom GSK Investigational Site Manchester, United Kingdom, M23 9LT 收起 <<
NCT02177344	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 3	Completed	-	-
NCT03480997	COPD	Phase 1	Completed	-	United States, North Carolina ... 展开 >> Advanced Respiratory and Sleep Medicine, PLLC Hickory, North Carolina, United States, 28601 收起 <<
NCT00381589	Hypersalivation	Not Applicable	Completed	-	Canada, Ontario ... 展开 >> Centre for Addiction and Mental Health Toronto, Ontario, Canada, M5T 1R8 收起 <<
NCT02235428	Asthma	Phase 4	Terminated	-	-
NCT01944033	Acute Exacerbation of Chronic ... 展开 >>Obstructive Airways Disease 收起 <<	Phase 3	Completed	-	Tunisia ... 展开 >> University Hospital of Monastir Monastir,, Monastir, Tunisia, 5000 Fattouma Bourguiba University Hospital Monastir, Tunisia, 5000 收起 <<
NCT02260011	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 2	Completed	-	-
NCT01691482	-		Completed	-	-
NCT03136120	-		Recruiting	December 18, 2018	United Kingdom ... 展开 >> GSK Investigational Site Recruiting London, United Kingdom, NW1 2PG Contact: US GSK Clinical Trials Call Center 877-379-3718 GSKClinicalSupportHD@gsk.com Contact: EU GSK Clinical Trials Call Center +44 (0) 20 8990 4466 GSKClinicalSupportHD@gsk.com 收起 <<
NCT00605410	Asthma	Phase 4	Completed	-	Canada, Saskatchewan ... 展开 >> University of Saskatchewan Saskatoon, Saskatchewan, Canada, S7N oW8 收起 <<
NCT02236182	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 2	Completed	-	-
NCT01943552	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 4	Completed	-	China ... 展开 >> 244.2514.86008 Boehringer Ingelheim Investigational Site Chengdu, China 244.2514.86006 Boehringer Ingelheim Investigational Site Guangzhou, China 244.2514.86007 Boehringer Ingelheim Investigational Site Guangzhou, China 244.2514.86010 Boehringer Ingelheim Investigational Site Guangzhou, China 244.2514.86009 Boehringer Ingelheim Investigational Site Hangzhou, China 244.2514.86004 Boehringer Ingelheim Investigational Site Shanghai, China 244.2514.86002 Boehringer Ingelheim Investigational Site Tianjin, China 244.2514.86011 Boehringer Ingelheim Investigational Site Wuhan, China 244.2514.86012 Boehringer Ingelheim Investigational Site Wuhan, China 收起 <<
NCT00583778	Asthma	Not Applicable	Completed	-	United States, Ohio ... 展开 >> MetroHealth Medical Center Cleveland, Ohio, United States, 44109 收起 <<
NCT01691079	Bronchospasm, Exercise-Induced	Phase 4	Completed	-	United States, California ... 展开 >> University of California, San Francisco San Francisco, California, United States, 94143 收起 <<
NCT00911651	COPD	Phase 4	Completed	-	Belgium ... 展开 >> Antwerp University Hospital Antwerp, Belgium, 2650 收起 <<
NCT03747536	Sialorrhea	Phase 2	Not yet recruiting	January 1, 2021	-
NCT01943552	-		Completed	-	-
NCT02755714	Exercise Induced Laryngeal Obs... 展开 >>truction (EILO) 收起 <<	Phase 1 Phase 2	Recruiting	May 1, 2021	Norway ... 展开 >> Haukeland University Hospital Recruiting Bergen, Norway, 5021 Contact: Thomas Halvorsen, MD and PhD +47 9246 4843 thomas.halvorsen@helse-bergen.no 收起 <<
NCT02236169	Pulmonary Disease, Chronic Obs... 展开 >>tructive 收起 <<	Phase 2	Completed	-	-

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