皂苷元 D /Saikogenin D
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货号：A1144439
同义名：
柴胡皂甙元 D
Saikogenin D从 Bupleurum chinense 中分离，具有抗炎作用。它激活环氧合酶，将花生四烯酸转化为环氧二十烷酸和二羟基二十碳三烯酸，从而抑制前列腺素E2 (PGE2) 的生成。由于细胞内 Ca2+的释放，Saikogenin D 还会引起 Ca2+的升高。
Saikogenin D 化学结构
CAS号：5573-16-0
Saikogenin D 3D分子结构
CAS号：5573-16-0
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Saikogenin D 纯度/质量文件 产品仅供科研
货号：A1144439
标准纯度：
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Saikogenin D 质控信息
| CDC25B-IN-2 |
✔
|
|
|
Akt
|
99%+ |
| Clevidipine |
|
✔
|
|
|
97% |
| Verapamil HCl |
|
✔
|
|
|
99% |
| Amlodipine |
|
✔
|
|
|
99% |
| Amlodipine maleate |
|
✔
|
|
|
98% |
| (+)-cis-Diltiazem HCl |
|
✔
|
|
|
95% |
| Zegocractin |
|
++
Orai1/STIM1-mediated Ca2+ currents, IC50: 120 nM
|
|
|
99%+ |
| Tanshinone IIA sulfonate sodium |
|
✔
|
|
|
98% |
| Ulixacaltamide |
|
++
hCaV3.1, IC50: 50 nM
hCaV3.2, IC50: 110 nM
|
|
|
99%+ |
| Dronedarone Hydrochloride |
|
✔
|
|
|
95% |
| Nitrendipine |
|
+
Calcium channel, IC50: 95 nM
|
|
|
98% |
| Efonidipine HCl monoethanolate |
|
✔
|
|
|
98% |
| Cinnarizine |
|
✔
|
|
|
98% |
| SEA0400 |
|
++
|
|
ROS,ERK,p38 MAPK
|
99%+ |
| Fasudil HCl |
|
✔
|
|
Rho,PKA
|
98% |
| ML-9 |
|
✔
|
|
Akt,MLCK
|
99%+ |
| Flunarizine 2HCl |
|
+
Calcium channel, Ki: 68 nM
|
|
|
95% |
| Lomerizine 2HCl |
|
✔
|
|
|
98% |
| Efonidipine |
|
✔
|
|
|
98% |
| Levamlodipine |
|
✔
|
|
|
97% |
| Nisoldipine |
|
++
L-type Cav1.2, IC50: 10 nM
|
|
|
97% |
| Isradipine |
|
✔
|
|
|
98% |
| Lacidipine |
|
✔
|
|
|
98% |
| Lercanidipine |
|
✔
|
|
|
98% |
| Loureirin B |
|
✔
|
|
Potassium Channel
|
99%+ |
| Tetracaine HCl |
|
✔
|
|
|
98% |
| Manidipine |
|
+++
Calcium channel, IC50: 2.6 nM
|
|
|
98% |
| Manidipine Dihydrochlorid |
|
+++
Calcium channel, IC50: 2.6 nM
|
|
|
98% |
| Nicardipine |
|
✔
|
|
|
98% |
| Wilforgine |
|
✔
|
|
|
98+% |
| Econazole |
|
✔
|
|
|
99%+ |
| Ginsenoside Rd |
|
✔
|
|
NF-κB
|
98% |
| Fendiline HCl |
|
✔
|
|
|
98+% |
| Mesaconitine |
|
✔
|
|
|
98% |
| Tetrandrine |
|
✔
|
|
|
95% |
| Nifedipine |
|
✔
|
|
|
95% |
| Nilvadipine |
|
++++
Calcium channel, IC50: 0.03 nM
|
|
|
98% |
| Barnidipine |
|
++++
[3H]nitrendipine, Ki: 0.21 nM
|
|
|
95+% |
| Azelnidipine |
|
✔
|
|
|
97% |
| Levetiracetam |
|
✔
|
|
|
98% |
| Nimodipine |
|
✔
|
|
|
95% |
| Benidipine HCl |
|
✔
|
|
|
98% |
| Pinaverium bromide |
|
✔
|
|
|
98% |
| Pranidipine |
|
✔
|
|
|
98% |
| NP118809 |
|
+
N-type Ca2+ channel, IC50: 0.11 μM
L-type calcium channel, IC50: 12.2 μM
|
|
|
98% |
| Amlodipine Besylate |
|
+++
Calcium channel, IC50: 1.9 nM
|
|
|
97% |
| Cilnidipine |
|
✔
|
|
|
98% |
| Cinepazide Maleate |
|
✔
|
|
|
98% |
| Terfenadine |
|
✔
|
|
|
98% |
| YM-58483 |
|
✔
|
|
|
99%+ |
| Ranolazine |
|
✔
|
|
|
98% |
| Praeruptorin A |
|
✔
|
|
Akt,p38 MAPK
|
98% |
| Ranolazine 2HCl |
|
✔
|
|
|
98% |
| Felodipine |
|
++++
L-type calcium channel, IC50: 0.15 nM
|
|
|
98% |
| PD173212 |
|
+++
N-type Ca2+ channel, IC50: 36 nM
|
|
|
98% |
| Levamlodipine besylate |
|
✔
|
|
|
97% |
| Carboxyamidotriazole Orotate |
|
✔
|
|
|
98% |
| IGS-1.76 |
|
✔
|
|
|
98+% |
| WH-4-023 |
|
++++
|
++++
|
|
99%+ |
|
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
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Saikogenin D 实验方案
| 计算器 |
|
| 存储液制备 |
 |
1mg |
5mg |
10mg |
|
1 mM
5 mM
10 mM
|
2.12mL
0.42mL
0.21mL
|
10.58mL
2.12mL
1.06mL
|
21.16mL
4.23mL
2.12mL
|
Saikogenin D 技术信息
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