左旋氨氯地平 /Levamlodipine
97%
货号：A707253
同义名：
（S）-氨氯地平
/ (S)-Amlodipine;Levoamlodipine
Levamlodipine ((S)-Amlodipine) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina.
Levamlodipine 化学结构
Levamlodipine 3D分子结构
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Levamlodipine 纯度/质量文件 产品仅供科研
货号：A707253
标准纯度：
97%
产品说明书
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Levamlodipine 质控信息
CDC25B-IN-2
✔
Akt
99%+
Clevidipine
✔
97%
Verapamil HCl
✔
99%
Amlodipine
✔
99%
Amlodipine maleate
✔
98%
(+)-cis-Diltiazem HCl
✔
95%
Zegocractin
++
Orai1/STIM1-mediated Ca2+ currents, IC50: 120 nM
99%+
Tanshinone IIA sulfonate sodium
✔
98%
Ulixacaltamide
++
hCaV3.2, IC50: 110 nM
hCaV3.1, IC50: 50 nM
99%+
Dronedarone Hydrochloride
✔
95%
Nitrendipine
+
Calcium channel, IC50: 95 nM
98%
Efonidipine HCl monoethanolate
✔
98%
Cinnarizine
✔
98%
SEA0400
++
ROS,ERK,p38 MAPK
99%+
Fasudil HCl
✔
Rho,PKA
98%
ML-9
✔
MLCK,Akt
99%+
Flunarizine 2HCl
+
Calcium channel, Ki: 68 nM
95%
Lomerizine 2HCl
✔
98%
Efonidipine
✔
98%
Levamlodipine
✔
97%
Nisoldipine
++
L-type Cav1.2, IC50: 10 nM
97%
Isradipine
✔
98%
Lacidipine
✔
98%
Lercanidipine
✔
98%
Loureirin B
✔
Potassium Channel
99%+
Tetracaine HCl
✔
98%
Manidipine
+++
Calcium channel, IC50: 2.6 nM
98%
Manidipine Dihydrochlorid
+++
Calcium channel, IC50: 2.6 nM
98%
Nicardipine
✔
98%
Wilforgine
✔
98+%
Econazole
✔
99%+
Ginsenoside Rd
✔
NF-κB
98%
Fendiline HCl
✔
98+%
Mesaconitine
✔
98%
Tetrandrine
✔
95%
Nifedipine
✔
95%
Nilvadipine
++++
Calcium channel, IC50: 0.03 nM
98%
Barnidipine
++++
[3 H]nitrendipine, Ki: 0.21 nM
95+%
Azelnidipine
✔
97%
Levetiracetam
✔
98%
Nimodipine
✔
95%
Benidipine HCl
✔
98%
Pinaverium bromide
✔
98%
Pranidipine
✔
98%
NP118809
+
L-type calcium channel, IC50: 12.2 μM
N-type Ca2+ channel, IC50: 0.11 μM
98%
Amlodipine Besylate
+++
Calcium channel, IC50: 1.9 nM
97%
Cilnidipine
✔
98%
Cinepazide Maleate
✔
98%
Terfenadine
✔
98%
YM-58483
✔
99%+
Ranolazine
✔
98%
Praeruptorin A
✔
p38 MAPK,Akt
98%
Ranolazine 2HCl
✔
98%
Felodipine
++++
L-type calcium channel, IC50: 0.15 nM
98%
PD173212
+++
N-type Ca2+ channel, IC50: 36 nM
98%
Levamlodipine besylate
✔
97%
Carboxyamidotriazole Orotate
✔
98%
IGS-1.76
✔
98+%
WH-4-023
++++
++++
99%+
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1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
Levamlodipine 生物活性
靶点
描述
Levamlodipine is a calcium channel blocker drug. Levamlodipine (LEE) is a drug commonly used for antihypertensive treatment in clinical therapy[2] [3] [4]
Levamlodipine 参考文献
[1] Jain R, et al. Polyaniline-graphene oxide nanocomposite sensor for quantification of calcium channel blocker levamlodipine. Mater Sci Eng C Mater Biol Appl. 2016 Aug 1;65:205-14.
[2] Liu Z, Huang X, Jiang Z, Tuo X. Investigation of the binding properties between levamlodipine and HSA based on MCR-ALS and computer modeling. Spectrochim Acta A Mol Biomol Spectrosc. 2021 Jan 15;245:118929
[3] Gui H, Guo YF, Liu X, Zhang JM, Yang YL, Huang GZ, Liu JG. Effects of combination therapy with levamlodipine and bisoprolol on stroke in rats. CNS Neurosci Ther. 2013 Mar;19(3):178-82
[4] Yang YL, Yu LT, Wu ZT, Yu JG, Zhang JM, Chen QH, Bao YC, Liu JG. Synergic effects of levamlodipine and bisoprolol on blood pressure reduction and organ protection in spontaneously hypertensive rats. CNS Neurosci Ther. 2012 Jun;18(6):471-4
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Levamlodipine 实验方案
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摩尔计算器
总药量计算器
工作液计算器
存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
2.45mL
0.49mL
0.24mL
12.23mL
2.45mL
1.22mL
24.46mL
4.89mL
2.45mL
Levamlodipine 技术信息
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