Saikogenin D从 Bupleurum chinense 中分离，具有抗炎作用。它激活环氧合酶，将花生四烯酸转化为环氧二十烷酸和二羟基二十碳三烯酸，从而抑制前列腺素E2 (PGE2) 的生成。由于细胞内 Ca²⁺的释放，Saikogenin D 还会引起 Ca²⁺的升高。

Saikosaponin D, a natural product isolated and purified from the herb of Bupleurum chinense DC., is a SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity and a potent inhibitor on acute hepatic injury by CCl4 and a potent cytotoxicity agent for human hepatocellular carcinoma cells, and has the antiproliferative effect in A549 cells that may be the induction of p53 and activity of the Fas/FasL apoptotic system.

Saikosaponin B2, a natural product isolated and purified from the herb of Bupleurum chinense DC., acts on HCV E2, inhibits infection by several genotypic strains and prevents binding of serum-derived HCV onto hepatoma cells, and induces differentiation of B16 melanoma cells at a concentration of 5 mM, with potentiation of expressions of melanogenesis and tyrosinase.

Saikosaponin C, a natural product isolated and purified from the root of Bupleurum chinense DC., with antioxidant, anti-inflammatory and cytotoxic activities, has an inhibitory activity against allergic asthma. It also shows an inhibitory for cell growth and DNA synthesis with 50-μg/mL.

Saikosaponin A, a natural product isolated and purified from the root of Bupleurum chinense DC., with antioxidant activity, has an inhibitory activity against allergic asthma and an anti-inflammatory activity by inhibiting the MAPK and NF-κB pathways in LPS-stimulated RAW 264.7 cells, shows the most potent cytotoxicity against human cancer cells, and is an inhibitory for cell growth and DNA synthesis with 50-μg/mL.

Saikosaponin B1, a natural product isolated and purified from the herb of Bupleurum chinense DC., potently stimulats PGE2 release.

Kaerophyllin, a natural product isolated and purified from the roots of Bupleurum chinense DC., protects the rat liver from TAA-caused injury and fibrogenesis by suppressing hepatic inflammation and inhibiting HSC activation, possibly through upregulation of PPAR-γ expression, and inhibits AB-induced LX-2 activation and migration with downregulation of Akt/ERK phosphorylations and NF-κB activity.

Isosalicifolin is a natural product isolated and purified from the herbs of Bupleurum candollei.

α-Spinasterol is an efficacious and safe antagonist of the TRPV1 receptor with antinociceptive effect.