桧木醇 /Hinokitiol 货号：A161005 同义名：
β-桧木醇
/ β-Thujaplicin;NSC 18804
Hinokitiol 是一种天然存在的单萜酚，具有抗氧化、抗菌、抗炎和抗肿瘤活性，可调节铁代谢并通过降低 Nrf2 的表达影响 DNA 甲基化相关蛋白的表达。
Hinokitiol 化学结构 Hinokitiol 3D分子结构 规格 价格 库存 数量
100μL*10mM(DMSO)
￥99随货￥69
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250μL*10mM(DMSO)
￥129随货￥99
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500μL*10mM(DMSO)
￥239随货￥169
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10mM*1mL(DMSO)
￥308
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25mg
￥210
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50mg
￥252
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100mg
￥473
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1g
￥4725
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Hinokitiol 纯度/质量文件 产品仅供科研 全球学术期刊中引用的产品
• ACS Appl. Nano Mater. , 2025. Ambeed. A188026
]
• Eur. J. Clin. Microbiol. Infect. Dis. , 2025. Ambeed. A151161
]
• JJC , 2025, 20(Special Issue)): 27-39. Ambeed. • bioRxiv , 2025. Ambeed. A538667 ,
A714873 ,
A126729 ,
A126049 ,
A446054
]
• Nature Communications , 2025, 16, 1871. Ambeed. A508148
]
更多 > Hinokitiol 质控信息
CDC25B-IN-2
✔
Akt 99%+ Clevidipine
✔
97% Verapamil HCl
✔
99% Amlodipine
✔
99% Amlodipine maleate
✔
98% (+)-cis-Diltiazem HCl
✔
99% Zegocractin
++
Orai1/STIM1-mediated Ca2+ currents, IC50: 120 nM
99%+ Tanshinone IIA sulfonate sodium
✔
98% Ulixacaltamide
++
hCaV3.1, IC50: 50 nM
hCaV3.2, IC50: 110 nM
99%+ Dronedarone HCl
✔
95% Nitrendipine
+
Calcium channel, IC50: 95 nM
98% Efonidipine HCl monoethanolate
✔
98% Cinnarizine
✔
98% SEA0400
++
p38 MAPK,ROS,ERK 99%+ Fasudil HCl
✔
Rho,PKA 98% ML-9
✔
Akt,MLCK 99%+ Flunarizine 2HCl
+
Calcium channel, Ki: 68 nM
95% Lomerizine 2HCl
✔
98% Efonidipine
✔
98% Levamlodipine
✔
98% Nisoldipine
++
L-type Cav1.2, IC50: 10 nM
97% Isradipine
✔
98% Lacidipine
✔
98% Lercanidipine
✔
99% Loureirin B
✔
Potassium Channel 99%+ Tetracaine HCl
✔
98% Manidipine
+++
Calcium channel, IC50: 2.6 nM
99% Manidipine Dihydrochlorid
+++
Calcium channel, IC50: 2.6 nM
98% Nicardipine
✔
99% Wilforgine
✔
98+% Econazole
✔
99%+ Ginsenoside Rd
✔
NF-κB 98% Fendiline HCl
✔
98+% Mesaconitine
✔
98% Tetrandrine
✔
95% Nifedipine
✔
95% Nilvadipine
++++
Calcium channel, IC50: 0.03 nM
98% Barnidipine
++++
[3 H]nitrendipine, Ki: 0.21 nM
95+% Azelnidipine
✔
97% Levetiracetam
✔
98% Nimodipine
✔
95% Benidipine HCl
✔
98% Pinaverium bromide
✔
98% Pranidipine
✔
99% NP118809
+
N-type Ca2+ channel, IC50: 0.11 μM
L-type calcium channel, IC50: 12.2 μM
98% Amlodipine Besylate
+++
Calcium channel, IC50: 1.9 nM
97% Cilnidipine
✔
99% Cinepazide Maleate
✔
99% (HPLC) Terfenadine
✔
98% YM-58483
✔
99%+ Ranolazine
✔
98% Praeruptorin A
✔
p38 MAPK,Akt 98% Ranolazine 2HCl
✔
98% Felodipine
++++
L-type calcium channel, IC50: 0.15 nM
98% PD173212
+++
N-type Ca2+ channel, IC50: 36 nM
98% Levamlodipine besylate
✔
97% Carboxyamidotriazole Orotate
✔
98% IGS-1.76
✔
98+% WH-4-023
++++
++++
99%+ 展开 1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
Hinokitiol 生物活性 描述 Hinokitiol, a tropolone-related natural compound, is known to induce apoptosis and cell cycle arrest and has anti-inflammatory and anti-tumor activities. Hinokitiol may exert DNA demethylation by inhibiting the expression of DNMT1 (DNA methyltransferase 1) and UHRF1 (RING finger domain 1) in colon cancer cells[3] [4] [5] [6]
Hinokitiol 参考文献 [1] Lee JH, Moon JH, et al. SIRT1, a Class III histone deacetylase, regulates LPS-induced inflammation in human keratinocytes and mediates the anti-inflammatory effects of hinokitiol. J Invest Dermatol. 2017 Feb 28. pii: S0022-202X(17)31149-1.
[2] Seo JS, Choi YH, et al. Hinokitiol induces DNA demethylation via DNMT1 and UHRF1 inhibition in colon cancer cells. BMC Cell Biol. 2017 Feb 27;18(1):14.
[3] Seo JS, Choi YH, Moon JW, Kim HS, Park SH. Hinokitiol induces DNA demethylation via DNMT1 and UHRF1 inhibition in colon cancer cells. BMC Cell Biol. 2017;18(1):14.
[4] Ouyang WC, Liao YW, Chen PN, Lu KH, Yu CC, Hsieh PL. Hinokitiol suppresses cancer stemness and oncogenicity in glioma stem cells by Nrf2 regulation. Cancer Chemother Pharmacol. 2017;80(2):411‐419
[5] Lu WJ, Lin KH, Tseng MF, et al. New therapeutic strategy of hinokitiol in haemorrhagic shock-induced liver injury. J Cell Mol Med. 2019;23(3):1723‐1734
[6] Jayakumar T, Liu CH, Wu GY, et al. Hinokitiol Inhibits Migration of A549 Lung Cancer Cells via Suppression of MMPs and Induction of Antioxidant Enzymes and Apoptosis. Int J Mol Sci. 2018;19(4):939.
展开 Hinokitiol 实验方案 计算器 摩尔计算器 总药量计算器 工作液计算器 存储液制备 1mg 5mg 10mg 1 mM
5 mM
10 mM
6.09mL
1.22mL
0.61mL
30.45mL
6.09mL
3.05mL
60.90mL
12.18mL
6.09mL
Hinokitiol 技术信息
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