茴拉西坦 /Aniracetam
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货号：A890956
同义名：
阿尼西坦
/ Ro 13-5057;Memodrin
Aniracetam is an allosteric modulator of AMPAR which can reduce glutamate receptor desensitization and potentiate metabotropic glutamate receptor activity.
Aniracetam 化学结构
Aniracetam 3D分子结构
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Aniracetam 纯度/质量文件 产品仅供科研
货号：A890956
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Aniracetam 质控信息
Aniracetam 生物活性
描述
Aniracetam is another AMPAkine created by modifying the piracetam molecule by replacing the acetamide moiety with a 4-methoxybenzoyl group.aniracetam improved healthy rats’ performance on active avoidance tasks, and on radial arm maze tasks [3] [4] [5]
Aniracetam 参考文献
[1] Vaglenova J, Pandiella N, et al. Aniracetam reversed learning and memory deficits following prenatal ethanol exposure by modulating functions of synaptic AMPA receptors. Neuropsychopharmacology. 2008 Apr;33(5):1071-83. Epub 2007 Jul 4.
[2] Nakamura K, Kurasawa M. Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. Eur J Pharmacol. 2001 May 18;420(1):33-43.
[3] Phillips H, McDowell A, Mielby BS, Tucker IG, Colombo M. Aniracetam does not improve working memory in neurologically healthy pigeons. PLoS One. 2019 Apr 19;14(4):e0215612. doi: 10.1371/journal.pone.0215612. PMID: 31002681; PMCID: PMC6474613.
[4] Elston TW, Pandian A, Smith GD, Holley AJ, Gao N, Lugo JN. Aniracetam does not alter cognitive and affective behavior in adult C57BL/6J mice. PLoS One. 2014 Aug 6;9(8):e104443. doi: 10.1371/journal.pone.0104443. PMID: 25099639; PMCID: PMC4123976.
[5] Koliaki CC, Messini C, Tsolaki M. Clinical efficacy of aniracetam, either as monotherapy or combined with cholinesterase inhibitors, in patients with cognitive impairment: a comparative open study. CNS Neurosci Ther. 2012 Apr;18(4):302-12. doi: 10.1111/j.1755-5949.2010.00244.x. Epub 2011 Feb 26. PMID: 22070796; PMCID: PMC6493642.
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Aniracetam 实验方案
计算器
摩尔计算器
总药量计算器
工作液计算器
存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
4.56mL
0.91mL
0.46mL
22.81mL
4.56mL
2.28mL
45.61mL
9.12mL
4.56mL
Aniracetam 技术信息
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