Ambeed 大中华区 CN | ZH

中文 - ZH English - EN

Ambeed.cn

搜索

关键字搜索批量搜索

首页 收藏 购物车0
首页 / 抑制剂/激动剂 / 神经信号通路 / AChR / Cisatracurium besylate

苯磺顺阿曲库铵 /Cisatracurium besylate {[allProObj[0].p_purity_real_show]}

货号：A153975 同义名： 顺苯磺酸阿曲库铵 / 51W89 besylate;Cisatracurium besilate

Cisatracurium besylate is an antagonize of AchR and inhibits neuromuscular transmission, a nondepolarizing skeletal muscle relaxant.

Cisatracurium besylate 化学结构 CAS号：96946-42-8
Cisatracurium besylate 化学结构
CAS号：96946-42-8
Cisatracurium besylate 3D分子结构
CAS号：96946-42-8
Cisatracurium besylate 化学结构 CAS号：96946-42-8
Cisatracurium besylate 3D分子结构 CAS号：96946-42-8
规格 价格 会员价 库存 数量
{[ item.pr_size ]}

{[ getRatePrice(item.pr_rmb, 1,1) ]}

{[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ suihuo_tips(item.pr_am, item.pr_size) ]}

{[ getRatePrice(item.pr_rmb, 1,1) ]}

{[ getRatePrice(item.pr_rmb,item.pr_rate,1) ]} {[ suihuo_tips(item.pr_am, item.pr_size) ]} 		{[ getRatePrice(item.pr_rmb, 1,1) ]}{[ suihuo_tips(item.pr_am, item.pr_size) ]} {[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_rmb,1,item.mem_rate) ]} 现货 咨询 - +
购物车0 收藏 询单

Cisatracurium besylate 纯度/质量文件 产品仅供科研

货号：A153975 标准纯度： {[allProObj[0].p_purity_real_show]}
批次查询： 批次纯度:

全球学术期刊中引用的产品

• Nat. Biomed. Eng., 2024, 8, 1412-1424. Ambeed. [ A538667 , A631746 ]
• JMC, 2024. Ambeed. [ A833302 , A475501 , A341986 , A356070 ]
• BMC Cancer, 2024, 24(1): 1415. Ambeed. [ A809692 , A209020 ]
• J. Am. Soc. Mass Spectrom., 2024, 35(12): 3192-3202. Ambeed. [ A166127 , A902473 , A753371 , A961334 , A292945 , A230770 , A300620 , A1114580 , A1159765 , A206238 ]
• PloS One, 2024, 19(11): e0308060. Ambeed. [ A302917 ]
更多 >
产品名称 AChE ↓ AChR ↓ mAChR ↓ nAChR ↓ 其他靶点 纯度
Donepezil +++

hAChE, IC50: 11.6 nM

bAChE, IC50: 8.12 nM

 		98%
Loganin ++

AChE, IC50: 3.95 μM

 		99%+
topride HCl ++

AChE, IC50: 2.04 μM

 		98%
Dehydroevodiamine HCl ✔ 99%+
Jatrorrhizine ++

AChE, IC50: 872 nM

 		99%+
Palmatine ++

AChE, IC50: 0.51 μM

 		98%
(-)-Huperzine A ++++

AChE (G4 form), Ki: 7 nM

 		98%
Galanthamine HBr ++

AChE, IC50: 0.35 μM

 		98%
Trospium chloride ✔ 99%
Tiotropium Bromide Monohydrate ✔ 98+%
Gallamine Triethiodide +

AChR, IC50: 68.0 μM

 		98%
Hexamethonium Bromide ✔ 99%
Pancuronium dibromide ✔ 98%
Neostigmine bromide ✔ 98%
Orphenadrine citrate ✔ 98%
Oxybutynin ✔ 98%
Irsogladine ✔ PDE 98%
Pyridostigmine bromide ✔ 99+%
Rivastigmine +

AChR, IC50: 5.5 μM

 		98%
Paroxetine hydrochloride ✔ 97%
Rocuronium Bromide ✔ 98%
Tropicamide +++

M4 mAChR, IC50: 8 nM

 		98%
Diphenmanil methylsulfate ✔ 98%
Umeclidinium bromide ✔ 95%
Otilonium bromide ✔ 98%
Flavoxate HCl +

mAChR, IC50: 12.2 μM

 		98%
Ipratropium bromide ✔ 98%
Diphenidol HCl ✔ 98%
Darifenacin hydrobromide ++++

M3 mAChR, pKi: 8.9

 		98%
Aclidinium Bromide ++++

M4 mAChR, Ki: 0.21 nM

M2 mAChR, Ki: 0.1 nM

 		98%
Oxybutynin chloride ✔ 99%
Pentoxyverine citrate ✔ 98%
Solifenacin ✔ 98%
Catharanthine ✔ 98%
Benzethonium chloride +++

α4β2 nAChRs, IC50: 49 nM

α7 nAChRs, IC50: 122 nM

 		99+%
Vinblastine sulfate +

nAChR, IC50: 8.9 μM

 		99%
PNU-120596 ++

α7 nAChR, EC50: 216 nM

 		99+%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

Cisatracurium besylate 生物活性

靶点

  • Adrenergic Receptor
描述 Cisatracurium Besylate is an ideal non-depolarizing muscle relaxant. The inhibitory effect of cisatracurium besylate on the proliferation activity of endothelial cells was time-dependent. Cisatracurium Besylate (0, 5, 25, or 100 µM) make the number of the autolysomes increases in a concentration dependent manner. Moreover, cisatracurium besylate can injure cells through autophagic cell death[3]. Cisatracurium besylate is frequently used in the intensive care unit in order to induce muscle relaxation to facilitate mechanical ventilation in critically ill patients[4].

Cisatracurium besylate 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01181349 - Completed - -
NCT02793323 Relieve Shoulder Pain After La... 展开 >>paroscopic Surgeries 收起 << Not Applicable Completed - Lebanon ... 展开 >> Makassed General Hospital Beirut, Lebanon 收起 <<
NCT02154074 Perioperative Blood Glucose an... 展开 >>d Insulin 收起 << Phase 4 Unknown October 2014 China, Shanxi ... 展开 >> SecondXianJiaotongU Recruiting Xi'an, Shanxi, China Contact: Hongtao Liu    13572225310    lannylouis@163.com 收起 <<

Cisatracurium besylate 参考文献

[1]Zhang H, Wang P, et al. HPLC determination of cisatracurium besylate and propofol mixtures with LC-MS identification of degradation products. J Pharm Biomed Anal. 1998 Mar;16(7):1241-9.

[2]Dear GJ, Harrelson JC, et al. Identification of urinary and biliary conjugated metabolites of the neuromuscular blocker 51W89 by liquid chromatography/mass spectrometry. Rapid Commun Mass Spectrom. 1995;9(14):1457-64.

[3]Zhuang H, Tian W, Li W, Zhang X, Wang J, Yang Y, Liu X, Xia Z, Feng D, Zhang L. Autophagic Cell Death and Apoptosis Jointly Mediate Cisatracurium Besylate-Induced Cell Injury. Int J Mol Sci. 2016 Apr 6;17(4):515.

[4]Meeder AM, van der Steen MS, Rozendaal A, van Zanten AR. Phlebitis as a consequence of peripheral intravenous administration of cisatracurium besylate in critically ill patients. BMJ Case Rep. 2016 Oct 3;2016:bcr2016216448.

Cisatracurium besylate 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

0.80mL

0.16mL

0.08mL

4.02mL

0.80mL

0.40mL

8.04mL

1.61mL

0.80mL

Cisatracurium besylate 技术信息

CAS号96946-42-8
分子式C65H82N2O18S2
分子量 1243.479
别名 顺苯磺酸阿曲库铵 ;51W89 besylate;Cisatracurium besilate;Cisatracurium (besylate);51W89
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Sealed in dry,Store in freezer, under -20°C
溶解度

H2O: 50 mg/mL(40.21 mM)
动物实验配方

Tags: Cisatracurium besylate | 96946-42-8 | 51W89 besylate | Cisatracurium | Autophagy Inducer | Membrane Transporter/Ion Channel | Neuronal Signaling | Autophagy | nAChR | Autophagy | 仅供科研使用 | AmBeed-信号通路专用抑制剂 | Cisatracurium besylate 纯度/质量文件 | Cisatracurium besylate 亚型比较 | Cisatracurium besylate 生物活性 | Cisatracurium besylate 临床数据 | Cisatracurium besylate 参考文献 | Cisatracurium besylate 实验方案 | Cisatracurium besylate 技术信息

Ambeed 相关网站 Ambeed.cn Ambeed.com
Ambeed
关于我们
联系我们
资讯中心
网站地图
产品手册
  • 批次文件查询
    • 客户支持
    技术支持
    专业术语
    缩略词释义
    质量手册
    产品咨询
    计算器
    活动政策
    订购方法
    积分商城
    活动声明
    联系我们
    400-920-2911 sales@ambeed.cn tech@ambeed.cn
    Ambeed 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质用途提供服务。

    尊敬的 Ambeed 客户您好，
    请您选择所在区域，我们将转接对应客服为您服务！

    热门区域

    A

    B

    C

    F

    G

    H

    J

    L

    N

    Q

    S

    T

    X

    Y

    Z

    热 A B C F G H J L N Q S T X Y Z