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牛磺酸 /Taurine {[allProObj[0].p_purity_real_show]}

货号:A184453 同义名: 2-氨基乙磺酸 / 2-Aminoethanesulfonic acid;β-Aminoethylsulfonic Acid

Taurine is a widely distributed organic compound in animal tissues which possesses function of conjugation of bile acids, antioxidation, osmoregulation, membrane stabilization, and modulation of calcium signaling.

Taurine 化学结构 CAS号:107-35-7
Taurine 化学结构
CAS号:107-35-7
Taurine 3D分子结构
CAS号:107-35-7
Taurine 化学结构 CAS号:107-35-7
Taurine 3D分子结构 CAS号:107-35-7
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Taurine 纯度/质量文件 产品仅供科研

货号:A184453 标准纯度: {[allProObj[0].p_purity_real_show]}
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产品名称 Ca2+ channel-like protein Calcium Channel Cav 2.2 其他靶点 纯度
CDC25B-IN-2 Akt 99%+
Clevidipine 97%
Verapamil HCl 99%
Amlodipine 99%
Amlodipine maleate 98%
(+)-cis-Diltiazem HCl 95%
Zegocractin ++

Orai1/STIM1-mediated Ca2+ currents, IC50: 120 nM

99%+
Tanshinone IIA sulfonate sodium 98%
Ulixacaltamide ++

hCaV3.1, IC50: 50 nM

hCaV3.2, IC50: 110 nM

99%+
Dronedarone Hydrochloride 95%
Nitrendipine +

Calcium channel, IC50: 95 nM

98%
Efonidipine HCl monoethanolate 98%
Cinnarizine 98%
SEA0400 ++

NCX, IC50: 33 nM

ERK,ROS,p38 MAPK 99%+
Fasudil HCl PKA,Rho 98%
ML-9 Akt,MLCK 99%+
Flunarizine 2HCl +

Calcium channel, Ki: 68 nM

95%
Lomerizine 2HCl 98%
Efonidipine 98%
Levamlodipine 97%
Nisoldipine ++

L-type Cav1.2, IC50: 10 nM

97%
Isradipine 98%
Lacidipine 98%
Lercanidipine 98%
Loureirin B Potassium Channel 99%+
Tetracaine HCl 98%
Manidipine +++

Calcium channel, IC50: 2.6 nM

98%
Manidipine Dihydrochlorid +++

Calcium channel, IC50: 2.6 nM

98%
Nicardipine 98%
Wilforgine 98+%
Econazole 99%+
Ginsenoside Rd NF-κB 98%
Fendiline HCl 98+%
Mesaconitine 98%
Tetrandrine 95%
Nifedipine 95%
Nilvadipine ++++

Calcium channel, IC50: 0.03 nM

98%
Barnidipine ++++

[3H]nitrendipine, Ki: 0.21 nM

95+%
Azelnidipine 97%
Levetiracetam 98%
Nimodipine 95%
Benidipine HCl 98%
Pinaverium bromide 98%
Pranidipine 98%
NP118809 +

N-type Ca2+ channel, IC50: 0.11 μM

L-type calcium channel, IC50: 12.2 μM

98%
Amlodipine Besylate +++

Calcium channel, IC50: 1.9 nM

97%
Cilnidipine 98%
Cinepazide Maleate 98%
Terfenadine 98%
YM-58483 99%+
Ranolazine 98%
Praeruptorin A Akt,p38 MAPK 98%
Ranolazine 2HCl 98%
Felodipine ++++

L-type calcium channel, IC50: 0.15 nM

98%
PD173212 +++

N-type Ca2+ channel, IC50: 36 nM

98%
Levamlodipine besylate 97%
Carboxyamidotriazole Orotate 98%
IGS-1.76 98+%
WH-4-023 ++++

Cav 2.2, IC50: 0.001 μM

++++

Cav 2.2, IC50: 0.001 μM

99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。

Taurine 生物活性

描述 Taurine, is an organic acid which is not utilized in protein synthesis, but rather is found free or in simple peptides. Taurine has many fundamental biological roles such as conjugation of bile acids, antioxidation, osmoregulation, membrane stabilization, and modulation of calcium signaling.Taurine (5, 10, and 20 mmol/L) promoted Ca2+ uptake in a concentration-dependent manner, as well as concentration dependently reducing the homocysteine (0.5 mmol/L)-induced inhibition of mitochondrial Ca2+ uptake[3].

Taurine 参考文献

[1]Huxtable RJ. Taurine in the central nervous system and the mammalian actions of taurine. Prog Neurobiol. 1989;32(6):471-533.

[2]Chesney RW. Taurine: its biological role and clinical implications. Adv Pediatr. 1985;32:1-42.

[3]Chaudhry S, Tandon B, Gupta A, Gupta S. Taurine: A potential mediator for periodontal therapy. Indian J Dent Res. 2018 Nov-Dec;29(6):808-811. doi: 10.4103/ijdr.IJDR_123_17. PMID: 30589012.

Taurine 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

7.99mL

1.60mL

0.80mL

39.95mL

7.99mL

4.00mL

79.91mL

15.98mL

7.99mL

Taurine 技术信息

CAS号107-35-7
分子式C2H7NO3S
分子量 125.147
别名 2-氨基乙磺酸 ;2-Aminoethanesulfonic acid;β-Aminoethylsulfonic Acid;β-Aminoethylsulfonic Acid, NSC 32428, Taurine;NSC 32428
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Keep in dark place,Inert atmosphere,Room temperature

溶解度

DMSO: 1 mg/mL(7.99 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 25 mg/mL(199.77 mM),配合低频超声助溶

动物实验配方
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