There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
Topotecan Hydrochloride (SKF 104864A Hydrochloride) effectively inhibits the proliferation of human glioma cells and glioma stem cells (GSCs) in a dose- and time-dependent manner. An optimal administration concentration of 3 μM is selected based on IC50 values at 24 h. Topotecan Hydrochloride induces cell cycle arrest in G0/G1 and S phases and promotes apoptosis. Additionally, it inhibits cell viability in a dose-dependent manner [1].
体内研究
In the NUB-7 metastatic model, animals from all four groups are sacrificed after 14 days of treatment. Compared to the control group, low dose metronomic (LDM) Topotecan Hydrochloride and TP+Pazopanib (PZ) result in significantly lower liver weights in TP+PZ-treated animals compared to PZ alone. Microscopic tumors are observed in the livers of mice in all groups except TP+PZ, indicating the ability of Topotecan Hydrochloride+PZ to control liver metastasis. In previous dose-response studies, daily oral metronomic Topotecan Hydrochloride (0.5, 1.0, and 1.5 mg/kg) showed greater reduction in microvascular density compared to weekly maximum-tolerated dose regimen (7.5 and 15 mg/kg) in an ovarian cancer model. However, mice treated with 1.5 mg/kg daily oral Topotecan Hydrochloride exhibited decreased food intake and a lesser antitumor effect [2].
体外研究
Topotecan Hydrochloride (SKF 104864A Hydrochloride) effectively inhibits the proliferation of human glioma cells and glioma stem cells (GSCs) in a dose- and time-dependent manner. An optimal administration concentration of 3 μM is selected based on IC50 values at 24 h. Topotecan Hydrochloride induces cell cycle arrest in G0/G1 and S phases and promotes apoptosis. Additionally, it inhibits cell viability in a dose-dependent manner [1].
Topotecan HCl 细胞研究
细胞系
浓度
检测类型
检测时间
活动说明
数据源
A427 human lung carcinoma
Proliferation assay
Antiproliferative activity measured against A427 human lung carcinoma, IC50=49 nM
9876111
COR-L23/P cell
Cytotoxic assay
Cytotoxicity measured using the COR-L23 parental (COR-L23/P) human non small cell lung carcinoma cell line, IC50=13.2 nM
11806724
HeLa cells
Growth inhibition assay
Growth inhibition of HeLa cells after 4 days, GI50=30 nM
17418582
HT-29 cells
Cytotoxic assay
Cytotoxicity was determined in vitro in HT-29 cells(colon) of human tumor cell lines by using MTT assay, IC50=25 nM
Antiproliferative activity measured against A427 human lung carcinoma, IC50=49 nM
9876111
COR-L23/P cell
Cytotoxic assay
Cytotoxicity measured using the COR-L23 parental (COR-L23/P) human non small cell lung carcinoma cell line, IC50=13.2 nM
11806724
HeLa cells
Growth inhibition assay
Growth inhibition of HeLa cells after 4 days, GI50=30 nM
17418582
HT-29 cells
Cytotoxic assay
Cytotoxicity was determined in vitro in HT-29 cells(colon) of human tumor cell lines by using MTT assay, IC50=25 nM
7853331
human A2780 cells
Cytotoxic assay
72 h
Cytotoxicity against human A2780 cells overexpressing alpha5beta3 integrin assessed as cell survival after 72 hrs by SRB assay, IC50=6 nM
22959246
human A2780 cells
Cytotoxic assay
72 h
Cytotoxicity against human A2780 cells after 72 hrs by MTT assay, IC50=33 nM
24900725
human A375 cells
Cytotoxic assay
72 h
Cytotoxicity against human A375 cells after 72 hrs by alamar blue assay, IC50=13 nM
21341674
human A549 cells
Cytotoxic assay
96 h
Cytotoxicity against human A549 cells after 96 hrs by MTT assay, IC50=3.2 nM
15165144
human A549 cells
Function assay
4 h
Antitumor activity against human A549 cells after 4 hrs by MTT assay, IC50=5 nM
18207748
human Bel7402 cells
Cytotoxic assay
96 h
Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay, IC50=1.2 nM
15165144
human BGC823 cells
Cytotoxic assay
96 h
Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay, IC50=4.3 nM
15165144
human colon cancer cell line (WiDr)
Cytotoxic assay
In Vitro cytotoxicity against human colon cancer cell line (WiDr), IC50=56 nM
11334569
human colon carcinoma SW620 cell
Cytotoxic assay
Cytotoxic potentiation of Topotecan (TP) by the compound in human colon carcinoma SW620 cell line, IC50=3.2 nM
12408707
human DU145 cells
Growth inhibition assay
Growth inhibition of human DU145 cells by five-dose growth inhibition assay, IC50=10 nM
25909279
human GBM1 cells
Proliferation assay
72 h
Antiproliferative activity against human GBM1 cells assessed as reduction in cell viability incubated for 72 hrs by WST-1 method, IC50=0.46 μM
26355532
human GBM2 cells
Proliferation assay
72 h
Antiproliferative activity against human GBM2 cells assessed as reduction in cell viability incubated for 72 hrs by WST-1 method, IC50=0.13 μM
26355532
human GBM3 cells
Proliferation assay
72 h
Antiproliferative activity against human GBM3 cells assessed as reduction in cell viability incubated for 72 hrs by WST-1 method, IC50=0.38 μM
26355532
human H69 cells
Cytotoxic assay
72 h
Cytotoxicity against human H69 cells after 72 hrs by alamar blue assay, IC50=6 nM
21341674
human HCT116 cells
Growth inhibition assay
Growth inhibition of human HCT116 cells by five-dose growth inhibition assay, GI50=30 nM
25909279
human HCT8 cells
Cytotoxic assay
96 h
Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay, IC50=1.5 nM
15165144
human HCT8 cells
Cytotoxic assay
3 days
Cytotoxicity against human HCT8 cells after 3 days by MTT assay, IC50=70 nM
20392545
human Hep3B cells
Proliferation assay
72 h
Antiproliferative activity against human Hep3B cells after 72 hrs by XTT assay, GI50=0.22 μM
19796956
human HepG2 cells
Cytotoxic assay
4 days
Cytotoxicity against human HepG2 cells after 4 days by MTT assay, IC50=60 nM
18554906
human HL60 cells
Function assay
Antitumor activity against human HL60 cells by SRB method, IC50=12 nM
19541483
human HOP62 cells
Growth inhibition assay
Growth inhibition of human HOP62 cells by five-dose growth inhibition assay, IC50=10 nM
25909279
human HT1080 cells
Proliferation assay
48 h
Antiproliferative activity against human HT1080 cells assessed as growth inhibition incubated for 48 hrs by sulforhodamine B assay, IC50=0.18 μM
26408815
human IGROV1 cells
Cytotoxic assay
72 h
Cytotoxicity against human IGROV1 cells after 72 hrs by alamar blue assay, IC50=0.16 μM
21341674
human KB cells
Cytotoxic assay
72 h
Cytotoxicity against human KB cells after 72 hrs sulforhodamine B colorimetric assay, IC50=62.5 nM
25008456
human KB3-1 cells
Cytotoxic assay
Cytotoxicity against human KB3-1 cells after MTT assay, IC50=40 nM
18829334
human KBVIN cells
Cytotoxic assay
72 h
Cytotoxicity against human KBVIN cells after 72 hrs by SRB assay, IC50=0.4 μM
25438769
human Ketr3 cells
Cytotoxic assay
96 h
Cytotoxicity against human Ketr3 cells after 96 hrs by MTT assay, IC50=4.9 nM
15165144
human LNCAP cells
Cytotoxic assay
72 h
Cytotoxicity against human LNCAP cells after 72 hrs by alamar blue assay, IC50=9 nM
21341674
human LoVo cells
Cytotoxic assay
72 h
Cytotoxicity against human LoVo cells after 72 hrs by MTT assay, IC50=20 nM
20371183
human lung cancer cell line (H128)
Cytotoxic assay
In Vitro cytotoxicity against human lung cancer cell line (H128), IC50=31 nM
11334569
human lymphoblast tumor cell line RPM18402
Cytotoxic assay
Cytotoxicity against human lymphoblast tumor cell line RPM18402, IC50=12 nM
12392745
human MCF7 cells
Cytotoxic assay
96 h
Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay, IC50=1.8 nM
15165144
human MCF7 cells
Growth inhibition assay
Growth inhibition of human MCF7 cells by five-dose growth inhibition assay, IC50=10 nM
25909279
human MDA-MB-435 cells
Cytotoxic assay
72 h
Cytotoxicity against human MDA-MB-435 cells after 72 hrs by MTT assay, ic50=1 nM
20371183
human MDA-MB-435 cells
Cytotoxic assay
72 h
Cytotoxicity against human MDA-MB-435 cells incubated for 72 hrs by MTT assay, GI50=34 nM
22867019
human MESSA cells
Cytotoxic assay
72 h
Cytotoxicity against human MESSA cells after 72 hrs by alamar blue assay, IC50=4 nM
21341674
human MES-SA/Dx5 cells
Cytotoxic assay
Cytotoxicity against human MES-SA/Dx5 cells overexpressing MDR1 after 72 hrs by alamar blue assay, IC50=33 nM
21341674
human MOLT4 cells
Cytotoxic assay
72 h
Cytotoxicity against human MOLT4 cells after 72 hrs by MTT assay, IC50=19 nM
24900725
human NCI-H460 cells
Proliferation assay
72 h
Antiproliferative activity against human NCI-H460 cells after 72 hrs by coulter counter analysis, IC50=16 nM
21783369
human RPMI8226 cells
Cytotoxic assay
Cytotoxicity against human RPMI8226 cells by MTT method, IC50=21 nM
19012996
human SN12C cells
Growth inhibition assay
Growth inhibition of human SN12C cells by five-dose growth inhibition assay, GI50=20 nM
25909279
human stomach cancer cell line (MKN45)
Cytotoxic assay
In Vitro cytotoxicity against human stomach cancer cell line (MKN45), IC50=38 nM
11334569
human U251 cells
Function assay
6-24 h
Inhibition of topoisomerase-1 in human U251 cells assessed as inhibition of hypoxia-induced HIF-1alpha accumulation in nuclear extract after 6 to 24 hrs by immunoblot analysis, EC50=54 nM
22305612
human U87 cells
Proliferation assay
48 h
Antiproliferative activity against human U87 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50=0.16 μM
24826818
human U937 cells
Cytotoxic assay
48 h
Cytotoxicity against human U937 cells expressing p53 mutant after 48 hrs by SRB assay ， IC50=1.1 μM
19715319
human UACC62 cells
Growth inhibition assay
Growth inhibition of human UACC62 cells by five-dose growth inhibition assay, IC50=10 nM
25909279
LoVo cell line
Cytotoxic assay
Cytotoxic potentiation of Topotecan (TP) by the compound in (human colorectal cancer LoVo cell line, IC50=11.6 nM
12408707
LOX cells
Cytotoxic assay
Cytotoxicity was determined in vitro in LOX cells (melanoma) of human tumor cell lines by using MTT assay, IC50=5 nM
7853331
mouse P388 cells
Cytotoxic assay
Cytotoxicity against mouse P388 cells after MTT assay, IC50=45 nM
18829334
RPM18402 tumor cell line
Proliferation assay
Concentration required to inhibit cell proliferation in RPM18402 tumor cell line, IC50=20 nM
15482929
SK-BR-3 cells
Cytotoxic assay
In Vitro cytotoxicity against human breast cancer cell line (SK-BR-3), IC50=26 nM
11334569
SK-MEL-2 cells
Cytotoxic assay
72 h
Cytotoxicity against human SK-MEL-2 cells after 72 hrs by alamar blue assay, IC50=0.14 μM
21341674
UACC 62 cells
Cytotoxic assay
Tested in vitro for cytotoxicity against human tumor cell line UACC 62 (melanoma), GI50=30 nM
United States, New York
... 展开 >>
Montefiore Medical Center
Bronx, New York, United States, 10467-2490
NYU Cancer Institute
New York, New York, United States, 10016 收起 <<
Cancer
Carcin... 展开 >>oma
Fallopian Tube Cancer
Gynecological Malignancies
Metastases
Oncology
Ovarian Cancer
Solid Tumors
Tumors 收起 <<
Phase 1
Completed
-
United States, Arizona
... 展开 >>
Research Site
Tucson, Arizona, United States, 85724-5024
United States, California
Research Site
Sacramento, California, United States, 95817
United States, Florida
Research Site
Orlando, Florida, United States, 32806
Research Site
Tampa, Florida, United States, 33612
United States, Minnesota
Research Site
St. Louis Park, Minnesota, United States, 55426
United States, North Carolina
Research Site
Winston Salem, North Carolina, United States, 27103
United States, North Dakota
Research Site
Bismarck, North Dakota, United States, 58501
United States, Ohio
Research Site
Columbus, Ohio, United States, 43219
United States, Pennsylvania
Research Site
Philadelphia, Pennsylvania, United States, 19111
Australia, South Australia
Research Site
Adelaide, South Australia, Australia, 5000
Australia, Victoria
Research Site
Footscray, Victoria, Australia, 3011
Research Site
Parkville, Victoria, Australia, 3050
Belgium
Research Site
Leuven, Belgium, 3000
Research Site
Liège, Belgium, 4000
Research Site
Liège, Belgium, 4000
Research Site
Wilrijk, Belgium, 2610 收起 <<
Unspecified Adult Solid Tumor,... 展开 >> Protocol Specific 收起 <<
Phase 1
Completed
-
United States, California
... 展开 >>
City of Hope Medical Center
Duarte, California, United States, 91010
City of Hope Medical Group Inc
Pasadena, California, United States, 91105 收起 <<
Ovarian Cancer
... 展开 >> Fallopian Tube Cancer
Peritoneal Cancer 收起 <<
Phase 2
Completed
-
United States, Washington
... 展开 >>
Virginia Mason Medical Center
Seattle, Washington, United States, 98101
Puget Sound Oncology Consortium (PSOC)
Seattle, Washington, United States, 98104 收起 <<
United States, California
... 展开 >>
Childrens Hospital Los Angeles
Los Angeles, California, United States, 90027
United States, Connecticut
Connecticut Childrens Medical Center
Hartford, Connecticut, United States, 06106
United States, Delaware
Nemours/Alfred I. duPont Hospital for Children, Delaware
Wilmington, Delaware, United States, 19803
United States, Florida
University of Florida, Gainesville
Gainesville, Florida, United States, 32610
Nemours Children's Clinic, Jacksonville
Jacksonville, Florida, United States, 32207
University of Miami, Sylvester Comprehensive Cancer Center
Miami, Florida, United States, 33136
All Children's Hospital, St. Petersburg
St. Petersburg, Florida, United States, 33701
United States, New York
Montefiore Medical Center, Children's Hospital at Montefiore
Bronx, New York, United States, 10467
United States, Utah
Primary Children's Medical Center/Utah
Salt Lake City, Utah, United States, 84113 收起 <<
United States, Arizona
... 展开 >>
GSK Investigational Site
Tucson, Arizona, United States, 85712
United States, California
GSK Investigational Site
Concord, California, United States, 94520
GSK Investigational Site
Sacramento, California, United States, 95819
United States, Florida
GSK Investigational Site
Boca Raton, Florida, United States, 33486
GSK Investigational Site
Hollywood, Florida, United States, 33021
United States, Illinois
GSK Investigational Site
Chicago, Illinois, United States, 60612
United States, Indiana
GSK Investigational Site
Munster, Indiana, United States, 46321
United States, Louisiana
GSK Investigational Site
Metairie, Louisiana, United States, 70006
United States, Missouri
GSK Investigational Site
St. Louis, Missouri, United States, 63141
United States, New York
GSK Investigational Site
Bronx, New York, United States, 10467
United States, Texas
GSK Investigational Site
Amarillo, Texas, United States, 79106
United States, Virginia
GSK Investigational Site
Richmond, Virginia, United States, 23230
Poland
GSK Investigational Site
Poznan, Poland 收起 <<
Lung Cancer, Small Cell
... 展开 >> Solid Tumor Cancer 收起 <<
Phase 1
Completed
-
United States, New York
... 展开 >>
GSK Investigational Site
New York, New York, United States, 10021
United States, Pennsylvania
GSK Investigational Site
Philadelphia, Pennsylvania, United States, 19111
United States, Tennessee
GSK Investigational Site
Nashville, Tennessee, United States, 37203
United States, Texas
GSK Investigational Site
San Antonio, Texas, United States, 78229
Canada, Ontario
GSK Investigational Site
Ottawa, Ontario, Canada, K1H 1C4 收起 <<
Adult Acute Megakaryoblastic L... 展开 >>eukemia
Adult Acute Monoblastic Leukemia
Adult Acute Monocytic Leukemia
Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11
Adult Acute Myeloid Leukemia With Maturation
Adult Acute Myeloid Leukemia With Minimal Differentiation
Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11
Adult Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1
Adult Acute Myeloid Leukemia With t(9;11)(p22.3;q23.3); MLLT3-KMT2A
Adult Acute Myeloid Leukemia Without Maturation
Adult Acute Myelomonocytic Leukemia
Adult Erythroleukemia
Adult Pure Erythroid Leukemia
Chronic Myelomonocytic Leukemia
de Novo Myelodysplastic Syndrome
Essential Thrombocythemia
Hematopoietic and Lymphoid Cell Neoplasm
Myelodysplastic Syndrome
Philadelphia Chromosome Negative, BCR-ABL1 Positive Chronic Myelogenous Leukemia
Polycythemia Vera
Previously Treated Myelodysplastic Syndrome
Recurrent Adult Acute Lymphoblastic Leukemia
Recurrent Adult Acute Myeloid Leukemia
Recurrent Disease
Secondary Myelodysplastic Syndrome 收起 <<
Phase 1
Active, not recruiting
-
United States, Maryland
... 展开 >>
Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, United States, 21287
United States, Minnesota
Mayo Clinic
Rochester, Minnesota, United States, 55905 收起 <<
United States, Arkansas
... 展开 >>
GSK Investigational Site
Jonesboro, Arkansas, United States, 72401
United States, Florida
GSK Investigational Site
Gainesville, Florida, United States, 32605
GSK Investigational Site
Naples, Florida, United States, 34119
United States, Georgia
GSK Investigational Site
Athens, Georgia, United States, 30607
GSK Investigational Site
Macon, Georgia, United States, 31201
GSK Investigational Site
Marietta, Georgia, United States, 30060
United States, Mississippi
GSK Investigational Site
Jackson, Mississippi, United States, 39202
United States, Ohio
GSK Investigational Site
Cincinnati, Ohio, United States, 45236
United States, South Carolina
GSK Investigational Site
Mt. Pleasant, South Carolina, United States, 29464
United States, Tennessee
GSK Investigational Site
Chattanooga, Tennessee, United States, 37404
GSK Investigational Site
Memphis, Tennessee, United States, 38104
GSK Investigational Site
Memphis, Tennessee, United States, 38120
GSK Investigational Site
Nashville, Tennessee, United States, 37203
United States, Texas
GSK Investigational Site
Fort Worth, Texas, United States, 76104
United States, Washington
GSK Investigational Site
Seattle, Washington, United States, 98101-2795
United States, Wisconsin
GSK Investigational Site
Madison, Wisconsin, United States, 53792 收起 <<
Withdrawn(Cancelled before enr... 展开 >>ollment) 收起 <<
March 2011
United States, Minnesota
... 展开 >>
GSK Investigational Site
Rochester, Minnesota, United States, 55905
United States, Pennsylvania
GSK Investigational Site
Philadelphia, Pennsylvania, United States, 19104 收起 <<
United States, Alabama
... 展开 >>
Northeast Alabama Regional Medical Center
Anniston, Alabama, United States, 36207
United States, Arkansas
Northeast Arkansas Clinic
Jonesboro, Arkansas, United States, 72401
United States, Florida
Florida Cancer Specialists
Fort Myers, Florida, United States, 33901
Watson Clinic Center for Cancer Care and Research
Lakeland, Florida, United States, 33805
United States, Georgia
Northeast Georgia Medical Center
Gainesville, Georgia, United States, 30501
United States, Kentucky
Graves-Gilbert Clinic
Bowling Green, Kentucky, United States, 42101
Consultants in Blood Disorders and Cancer
Louisville, Kentucky, United States, 40207
United States, Louisiana
Hematology Oncology Life Center
Alexandria, Louisiana, United States, 71301
United States, Maine
Mercy Hospital
Portland, Maine, United States, 04101
United States, Michigan
Grand Rapids Clinical Oncology Program
Grand Rapids, Michigan, United States, 49503
United States, Montana
Montana Cancer Institute Foundation
Missoula, Montana, United States, 59802
United States, Ohio
Oncology Hematology Care
Cincinnati, Ohio, United States, 45242
United States, South Carolina
Spartanburg Regional Medical Center
Spartanburg, South Carolina, United States, 29303
United States, Tennessee
Associates in Hematology Oncology
Chattanooga, Tennessee, United States, 37404
Family Cancer Center
Collierville, Tennessee, United States, 38017
Tennessee Oncology, PLLC
Nashville, Tennessee, United States, 37023 收起 <<
Recurrent Small Cell Lung Canc... 展开 >>er
Unspecified Adult Solid Tumor, Protocol Specific 收起 <<
Phase 1
Phase 2
Completed
-
United States, Maryland
... 展开 >>
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Hospital
Baltimore, Maryland, United States, 21231
United States, New York
Memorial Sloan Kettering Cancer Center
New York, New York, United States, 10065 收起 <<
United States, New York
... 展开 >>
Columbia University Medical Center
Recruiting
New York, New York, United States, 10032
Contact: Laura Good, RN lg2824@cumc.columbia.edu
Principal Investigator: Jeffery Bruce, MD 收起 <<
Carcinoma, Non-Small -Cell Lun... 展开 >>g
Ovarian Neoplasms
Small Cell Lung Carcinoma
Uterine Cervical Neoplasms
Carcinoma, Neuroendocrine
Extrapulmonary Small Cell Cancer 收起 <<
Phase 1
Phase 2
Recruiting
October 30, 2025
United States, Maryland
... 展开 >>
National Institutes of Health Clinical Center, 9000 Rockville Pike
Recruiting
Bethesda, Maryland, United States, 20892
Contact: For more information at the NIH Clinical Center contact National Cancer Institute Referral Office 888-624-1937 收起 <<
United States, Arizona
... 展开 >>
Phoenix Children'S Hospital
Phoenix, Arizona, United States, 85016
United States, Colorado
University of Colorado Health Sciences Center and The Children's Hospital
Denver, Colorado, United States, 80045
United States, Florida
MD Anderson Cancer Center Orlando at Arnold Palmer Hospital for Children
Orlando, Florida, United States, 32806
United States, Missouri
Children's Mercy Hospital & Clinics
Kansas City, Missouri, United States, 64108
United States, New York
Memorial Sloan Kettering Cancer Center
New York, New York, United States, 10065
United States, Pennsylvania
Pennsylvania State University College of Medicine
Hershey, Pennsylvania, United States, 17110
Canada, Alberta
Alberta Children'S Hospital
Calgary, Alberta, Canada, T2N 1N4 收起 <<
United States, Arizona
... 展开 >>
GSK Investigational Site
Scottsdale, Arizona, United States, 85258
United States, New Hampshire
GSK Investigational Site
Lebanon, New Hampshire, United States, 03756
Korea, Republic of
GSK Investigational Site
Seoul, Korea, Republic of, 110-744
GSK Investigational Site
Seoul, Korea, Republic of, 120-752
Netherlands
GSK Investigational Site
Amsterdam, Netherlands, 1066 CX
GSK Investigational Site
Utrecht, Netherlands, 3584 CX 收起 <<
Cancer
Ovaria... 展开 >>n
Relapse
Chemotherapy 收起 <<
Phase 2
Terminated(lack of efficacy (i... 展开 >>ntermediate analysis)) 收起 <<
-
France
... 展开 >> Centre François Baclesse
Caen, Calvados, France, 14076
Centre Paul Papin
Angers, France, 49933
CHU Jean MINJOZ
Besancon, France, 25030
Institut Bergonié
Bordeaux, France, 33076
Centre G-F Leclerc
Dijon, France, 21076
CHD Les Oudairies
La ROCHE SUR YON, France, 85025
Centre Jean Bernard
Le MANS, France, 72015
Centre Val d'Aurelle
Montpellier, France, 34298
Centre azuréen de cancérologie
Mougins, France, 06250
Centre Alexis vautrin
Nancy, France, 54511
Centre Catherine de Sienne
Nantes, France, 44202
Centre René Gauducheau
Nantes, France, 44805
Centre Antoine Lacassagne
Nice, France, 06189
Hôpital Diaconesses
Paris, France, 75012
Institut CURIE
Paris, France, 75231
APHP Hopital TENON
Paris, France, 75970
Institut Jean Godinot
Reims, France, 51056
Institut de Cancérologie de la Loire
Saint Etienne, France, 42271
Centre Paul Strauss
Strasbourg, France, 67065
Institut Claudius regaud
Toulouse, France, 31052
Institut Gustave Roussy
Villejuif, France, 94805 收起 <<
Brain and Central Nervous Syst... 展开 >>em Tumors
Carcinoma of Unknown Primary
Leukemia
Lymphoma
Unspecified Childhood Solid Tumor, Protocol Specific 收起 <<
Phase 1
Terminated(Slow accrual and co... 展开 >>mpany withdrawing support to supply the drug) 收起 <<
-
United States, California
... 展开 >>
UCSF Helen Diller Family Comprehensive Cancer Center
San Francisco, California, United States, 94115
United States, District of Columbia
Children's National Medical Center
Washington, District of Columbia, United States, 20010-2970
United States, Illinois
Children's Memorial Hospital - Chicago
Chicago, Illinois, United States, 60614
United States, Maryland
Warren Grant Magnuson Clinical Center - NCI Clinical Trials Referral Office
Bethesda, Maryland, United States, 20892-1182
United States, Massachusetts
Dana-Farber/Harvard Cancer Center at Dana-Farber Cancer Institute
Boston, Massachusetts, United States, 02115
United States, North Carolina
Duke Comprehensive Cancer Center
Durham, North Carolina, United States, 27710
United States, Pennsylvania
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States, 19104-4318
Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15213
United States, Tennessee
St. Jude Children's Research Hospital
Memphis, Tennessee, United States, 38105
United States, Texas
Dan L. Duncan Cancer Center at Baylor College of Medicine
Houston, Texas, United States, 77030
United States, Washington
Children's Hospital and Regional Medical Center - Seattle
Seattle, Washington, United States, 98105 收起 <<
Korea, Republic of
... 展开 >>
Chungbuk University Hospital
Recruiting
Daegu, Korea, Republic of
Contact: Ki Hyung Lee 82-43-269-6015
Keimyung University Dongsan Center
Recruiting
Daegu, Korea, Republic of
Contact: Hong Suk Song 82-53-250-7436
National Cancer Center
Recruiting
Goyang, Korea, Republic of, 410-769
Contact: Heung Tai Kim 82-31-920-1622
Principal Investigator: Heung Tai Kim
Asan Medical Center
Recruiting
Seoul, Korea, Republic of
Contact: Sang We Kim 82-2-3010-3215
Chung-Ang University hospital
Recruiting
Seoul, Korea, Republic of
Contact: Joung Soon Jang 82-2-6299-1427
Kyung Hee University Medical Hospital
Recruiting
Seoul, Korea, Republic of
Contact: Jae Heon Jeong 82-2-958-8723
Seoul National University Boramae Medical Center
Recruiting
Seoul, Korea, Republic of
Contact: Jin Soo Kim 82-2-870-3202
Seoul National University Hospital
Recruiting
Seoul, Korea, Republic of
Contact: Dong Wan Kim 82-2-2072-2995
Seoul St. Marys Hospital
Recruiting
Seoul, Korea, Republic of
Contact: Jin Hyoung Kang 82-2-2258-2680
Seoul Veterans Hospital
Recruiting
Seoul, Korea, Republic of
Contact: Bong Seog Kim 82-2-2225-1319
Severance Hospital
Recruiting
Seoul, Korea, Republic of
Contact: Hye Ryeon Kim 82-10-8713-4793
Ajou University Hospital
Recruiting
Suwon, Korea, Republic of
Contact: Jin Hyuk Choi 82-31-219-4920
St. Vincents Hospital
Recruiting
Suwon, Korea, Republic of
Contact: Hoon Kyo Kim 82-2-540-7935 收起 <<
Recurrent Small Cell Lung Carc... 展开 >>inoma 收起 <<
Phase 2
Completed
-
United States, Arizona
... 展开 >>
Mayo Clinic in Arizona
Scottsdale, Arizona, United States, 85259
United States, Florida
Moffitt Cancer Center
Tampa, Florida, United States, 33612
United States, Georgia
Emory University/Winship Cancer Institute
Atlanta, Georgia, United States, 30322
United States, Iowa
University of Iowa/Holden Comprehensive Cancer Center
Iowa City, Iowa, United States, 52242
United States, Maryland
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Hospital
Baltimore, Maryland, United States, 21231
United States, Montana
Billings Clinic Cancer Center
Billings, Montana, United States, 59107
United States, Ohio
Case Western Reserve University
Cleveland, Ohio, United States, 44106
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States, 43210
United States, Tennessee
Vanderbilt University/Ingram Cancer Center
Nashville, Tennessee, United States, 37232
United States, Wisconsin
University of Wisconsin Hospital and Clinics
Madison, Wisconsin, United States, 53792
Singapore
Johns Hopkins Singapore
Singapore, Singapore, 308433 收起 <<
Cervical Cancer
... 展开 >> Endometrial Cancer
Fallopian Tube Cancer
Ovarian Cancer
Sarcoma
Vaginal Cancer
Vulvar Cancer 收起 <<
Phase 1
Completed
-
United States, Ohio
... 展开 >>
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center
Cleveland, Ohio, United States, 44106 收起 <<
United States, New Hampshire
... 展开 >>
GSK Investigational Site
Lebanon, New Hampshire, United States, 03756
United States, New York
GSK Investigational Site
Bronx, New York, United States, 10461
United States, Pennsylvania
GSK Investigational Site
Philadelphia, Pennsylvania, United States, 19111
United States, Tennessee
GSK Investigational Site
Nashville, Tennessee, United States, 37203
United States, Texas
GSK Investigational Site
San Antonio, Texas, United States, 78229
United States, West Virginia
GSK Investigational Site
Morgantown, West Virginia, United States, 26506
Netherlands
GSK Investigational Site
Amsterdam, Netherlands, 1066 CX
GSK Investigational Site
Utrecht, Netherlands, 3584 CX 收起 <<
Small Cell Lung Cancer
... 展开 >> Carcinoma, Small Cell 收起 <<
Phase 2
Completed
-
United States, Arkansas
... 展开 >>
Northeast Arkansas Clinic
Jonesboro, Arkansas, United States, 72401
United States, Florida
Florida Cancer Specialists
Fort Myers, Florida, United States, 33901
Watson Clinic Center for Cancer Care and Research
Lakeland, Florida, United States, 33805
Florida Hospital Cancer Institute
Orlando, Florida, United States, 32804
United States, Georgia
Northeast Georgia Medical Center
Gainesville, Georgia, United States, 30501
United States, Kentucky
Consultants in Blood Disorders and Cancer
Louisville, Kentucky, United States, 40207
United States, Louisiana
Hematology Oncology Life Center
Alexandria, Louisiana, United States, 71301
United States, Michigan
Grand Rapids Clinical Oncology Program
Grand Rapids, Michigan, United States, 49503
United States, Nebraska
Methodist Cancer Center
Omaha, Nebraska, United States, 68114
United States, Ohio
Oncology Hematology Care
Cincinnati, Ohio, United States, 45242
United States, South Carolina
Spartanburg Regional Medical Center
Spartanburg, South Carolina, United States, 29303
United States, Tennessee
Chattanooga Oncology Hematology Associates
Chattanooga, Tennessee, United States, 37404
Tennessee Oncology, PLLC
Nashville, Tennessee, United States, 37023 收起 <<
United States, Maryland
... 展开 >>
Johns Hopkins University/Sidney Kimmel Cancer Center
Recruiting
Baltimore, Maryland, United States, 21287
Contact: Site Public Contact 410-955-8804 jhcccro@jhmi.edu
Principal Investigator: Keith W. Pratz 收起 <<
United States, Arizona
... 展开 >>
Pinnacle Oncology Hematology
Scottsdale, Arizona, United States, 85258
United States, Colorado
University of Colorado Cancer Center
Aurora, Colorado, United States, 80045
United States, Illinois
Northwestern University
Chicago, Illinois, United States, 60611
United States, Ohio
Oncology Hematology Care
Cincinnati, Ohio, United States, 45242
United States, Oklahoma
University of Oklahoma
Oklahoma City, Oklahoma, United States, 73104
United States, South Carolina
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
United States, Tennessee
Tennessee Oncology, PLLC
Nashville, Tennessee, United States, 37203
United States, Washington
University of WA Seattle Cancer Care Alliance
Seattle, Washington, United States, 98109
United Kingdom
The Bays St Mary's Hospital
London, England, United Kingdom, W2 1NY
Sarah Cannon Research Instititute UK
London, England, United Kingdom, WIG 6AD 收起 <<
United States, Ohio
... 展开 >>
Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center
Recruiting
Cleveland, Ohio, United States, 44195
Contact: Michael A. Vogelbaum, MD, PhD 216-444-8564 vogelbm@ccf.org
Principal Investigator: Michael A. Vogelbaum 收起 <<
United States, Arizona
... 展开 >>
Mayo Clinic Hospital
Phoenix, Arizona, United States, 85054
Mayo Clinic in Arizona
Scottsdale, Arizona, United States, 85259
United States, California
University of California Davis Comprehensive Cancer Center
Sacramento, California, United States, 95817
United States, Colorado
University of Colorado Hospital
Aurora, Colorado, United States, 80045
United States, Florida
Mayo Clinic in Florida
Jacksonville, Florida, United States, 32224-9980
United States, Illinois
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, United States, 60637
UC Comprehensive Cancer Center at Silver Cross
New Lenox, Illinois, United States, 60451
University of Chicago Medicine-Orland Park
Orland Park, Illinois, United States, 60462
United States, Kansas
University of Kansas Clinical Research Center
Fairway, Kansas, United States, 66205
United States, Kentucky
University of Kentucky/Markey Cancer Center
Lexington, Kentucky, United States, 40536
United States, Minnesota
Mayo Clinic
Rochester, Minnesota, United States, 55905
United States, Pennsylvania
University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, United States, 15232
United States, Texas
Parkland Memorial Hospital
Dallas, Texas, United States, 75235
UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas, United States, 75390
United States, Utah
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, United States, 84112 收起 <<
United States, Minnesota
... 展开 >>
Masonic Cancer Center at University of Minnesota
Minneapolis, Minnesota, United States, 55455
Park Nicollet Cancer Center
Saint Louis Park, Minnesota, United States, 55416 收起 <<
United States, California
... 展开 >>
City of Hope Comprehensive Cancer Center
Duarte, California, United States, 91010
USC / Norris Comprehensive Cancer Center
Los Angeles, California, United States, 90033
University of California Davis Comprehensive Cancer Center
Sacramento, California, United States, 95817
City of Hope South Pasadena
South Pasadena, California, United States, 91030
United States, Michigan
Wayne State University/Karmanos Cancer Institute
Detroit, Michigan, United States, 48201
United States, Pennsylvania
Penn State Milton S Hershey Medical Center
Hershey, Pennsylvania, United States, 17033-0850
University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, United States, 15232 收起 <<
Central Nervous System (CNS) M... 展开 >>etastases
Brain Metastases 收起 <<
Phase 2
Withdrawn(No enrollment and PI... 展开 >> requested study termination per IRB system.) 收起 <<
-
United States, Texas
... 展开 >>
Houston Methodist Hospital
Houston, Texas, United States, 77030
Methodist Neurological Institute - Department of Neurosurgery
Houston, Texas, United States, 77030 收起 <<
United States, Ohio
... 展开 >>
Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center
Recruiting
Cleveland, Ohio, United States, 44195
Contact: Michael A Vogelbaum, MD, PhD 216-444-8564 vogelbm@ccf.org 收起 <<
Terminated(due to administrati... 展开 >>ve issue and financial sponsor decision to suspend ovarian cancer studies) 收起 <<
-
United States, New York
... 展开 >>
Bellevue Hospital Center
New York, New York, United States, 10016
NYU Clinical Cancer Center
New York, New York, United States, 10016
Tisch Hospital
New York, New York, United States, 10016 收起 <<
United States, California
... 展开 >>
Children's Hospital Los Angeles
Los Angeles, California, United States, 90027-0700
UCSF Comprehensive Cancer Center
San Francisco, California, United States, 94143
United States, Colorado
Children Hospital of Colorado
Aurora, Colorado, United States, 80045
United States, Georgia
Children's Healthcare of Atlanta
Atlanta, Georgia, United States, 30322
United States, Illinois
University of Chicago, Comer Children's Hospital
Chicago, Illinois, United States, 60637
United States, Massachusetts
Childrens Hospital Boston, Dana-Farber Cancer Institute.
Boston, Massachusetts, United States, 02115
United States, Michigan
C.S Mott Children's Hospital
Ann Arbor, Michigan, United States, 48109
United States, North Carolina
University of North Carolina
Chapel Hill, North Carolina, United States, 27599
United States, Ohio
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States, 45229-3039
United States, Texas
Cook Children's Healthcare System
Fort Worth, Texas, United States, 76104
United States, Washington
Children's Hospital and Regional Medical Center - Seattle
Seattle, Washington, United States, 98105
Canada, Ontario
Hospital for Sick Children
Toronto, Ontario, Canada, M5G 1X8 收起 <<
Small Cell Lung Cancer
... 展开 >> Ovarian Cancer 收起 <<
Phase 1
Phase 2
Recruiting
July 27, 2019
United States, Florida
... 展开 >>
Florida Cancer Specialists-Sarasota
Recruiting
Sarasota, Florida, United States, 34232
United States, Oklahoma
Oklahoma University Health Science Center/Stephenson Cancer Center
Recruiting
Oklahoma City, Oklahoma, United States, 73104
United States, Tennessee
Tennessee Oncology PLLC
Recruiting
Nashville, Tennessee, United States, 37203 收起 <<
United States, Arizona
... 展开 >>
Mayo Clinic in Arizona
Recruiting
Scottsdale, Arizona, United States, 85259
Contact: Kelly K. Curtis 480-301-8335 curtis.kelly1@mayo.edu
Principal Investigator: Kelly K. Curtis
United States, Florida
Mayo Clinic in Florida
Recruiting
Jacksonville, Florida, United States, 32224-9980
Contact: Steven Attia 904-953-2558 attia.steven@mayo.edu
Principal Investigator: Steven Attia
United States, Illinois
Northwestern University
Recruiting
Chicago, Illinois, United States, 60611
Contact: Mark Agulnik 312-695-1222 m-agulnik@northwestern.edu
Principal Investigator: Mark Agulnik
Northwestern University- Lake Forest Hospital
Recruiting
Lake Forest, Illinois, United States, 60045
Contact: Valerie Nelson, MD 847-582-2134
Principal Investigator: Valerie Nelson, MD
United States, Iowa
University of Iowa Hospitals and Clinics
Recruiting
Iowa City, Iowa, United States, 52242
Contact: Mohammed M. Milhem 319-356-2324 mohammed-milhem@uiowa.edu
Principal Investigator: Mohammed M. Milhem
United States, Minnesota
Masonic Cancer Center, University of Minnesota
Not yet recruiting
Minneapolis, Minnesota, United States, 55455
Contact: Keith M. Skubitz 612-625-5109 skubi001@umn.edu
Principal Investigator: Keith M. Skubitz
Mayo Clinic
Recruiting
Rochester, Minnesota, United States, 55905
Contact: Scott H. Okuno 507-284-4849 okuno.scott@mayo.edu
Principal Investigator: Scott H. Okuno
United States, Missouri
Washington University School of Medicine
Recruiting
Saint Louis, Missouri, United States, 63110
Contact: Brian A. Van Tine 314-747-8475 bvantine@dom.wustl.edu
Principal Investigator: Brian A. Van Tine
United States, Wisconsin
University of Wisconsin Hospital and Clinics
Not yet recruiting
Madison, Wisconsin, United States, 53792
Contact: Thomas A. McFarland 608-265-3890 Thomas.mcfarland@uwmf.wisc.edu
Principal Investigator: Thomas A. McFarland 收起 <<
Solid Tumors
... 展开 >>Central Nervous System Tumors 收起 <<
Phase 1
Phase 2
Recruiting
December 2018
Canada, Alberta
... 展开 >>
Alberta Children's Hospital
Recruiting
Calgary, Alberta, Canada
Contact: Pina Giuliano
Principal Investigator: Victor Lewis
Canada, British Columbia
BC Children's Hospital
Recruiting
Vancouver, British Columbia, Canada
Contact: Stephanie Badour
Contact: Jessica Davis
Principal Investigator: Rebecca Deyell
Canada, Manitoba
CancerCare Manitoba
Recruiting
Winnipeg, Manitoba, Canada
Contact: Rebekah Hiebert
Contact: Kathy Hjalmarsson
Principal Investigator: John Doyle
Canada, Nova Scotia
IWK Health Centre
Recruiting
Halifax, Nova Scotia, Canada
Contact: Lynn Russell
Principal Investigator: Jason Berman
Canada, Ontario
Children's Hospital of Eastern Ontario (CHEO)
Recruiting
Ottawa, Ontario, Canada
Contact: Isabelle LaForest
Principal Investigator: Donna Johnston
The Hospital for Sick Children
Recruiting
Toronto, Ontario, Canada
Contact: Gina Lee
Principal Investigator: Daniel Morgenstern
Canada, Quebec
CHU St. Justine Hopital
Recruiting
Montreal, Quebec, Canada
Contact: Dominique Lafreniere
Principal Investigator: Monia Marzouki 收起 <<
Small Cell Lung Cancer
... 展开 >> Small Cell Lung Cancer Limited Stage
Small Cell Lung Cancer Extensive Stage 收起 <<
Phase 2
Active, not recruiting
December 2018
France
... 展开 >> Annemasse - CH
Ambilly, France, 74100
Angers - CHU
Angers, France, 49000
CH
Colmar, France
CHRU Grenoble
Grenoble, France
Centre Hospitalier - Pneumologie
Le Mans, France, 72000
Lorient - CHBS
Lorient, France
Montpellier - CHRU
Montpellier, France, 34295
Mulhouse - CH
Mulhouse, France, 68000
Centre Antoine Lacassagne
Nice, France
AP-HP Hopital Tenon - Pneumologie
Paris, France, 75020
APHP - Paris Bichat
Paris, France, 75877
GH Paris Saint-Joseph
Paris, France
CHG de Pau
Pau, France
HCL - Lyon Sud (Pneumologie)
Pierre Bénite, France, 69495
Rouen - CHU
Rouen, France, 76000
Centre Hospitalier
Saint-Quentin, France
Toulouse - CHU Larrey
Toulouse, France
CHU Tours - Pneumologie
Tours, France 收起 <<
Extensive Stage Small Cell Lun... 展开 >>g Cancer
Recurrent Small Cell Lung Cancer 收起 <<
Phase 2
Terminated(Due to lack of acti... 展开 >>vity and slow accrual) 收起 <<
-
United States, Illinois
... 展开 >>
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, United States, 60637-1470
Decatur Memorial Hospital
Decatur, Illinois, United States
North Shore University Health System
Evanston, Illinois, United States
Ingalls Memorial Hospital
Ingalls Park, Illinois, United States
Illinois Cancer Care
Peoria, Illinois, United States 收起 <<
Brain and Central Nervous Syst... 展开 >>em Tumors 收起 <<
Phase 2
Completed
-
United States, Tennessee
... 展开 >>
St. Jude Children's Research Hospital
Memphis, Tennessee, United States, 38105
United States, Texas
Texas Children's Cancer Center
Houston, Texas, United States, 77030-2399
Australia, New South Wales
Children's Hospital at Westmead
Westmead, New South Wales, Australia, 2145
Australia, Victoria
Royal Children's Hospital
Parkville, Victoria, Australia, 3052 收起 <<
United States, Maryland
... 展开 >>
Medicine Invention Design Incorporation (MIDI) - IORG0007849
Bethesda, Maryland, United States, 20852
MIDI Clinical Trial Site Type 1 -c/o- Dr. Han Xu - Physicians assigned by CRO / IRB / IORG
Bethesda, Maryland, United States, 20852
MIDI Clinical Trial Site Type 2 -c/o- Dr. Han Xu - Investigators assigned by CRO / IRB / IORG
Bethesda, Maryland, United States, 20852
MIDI Clinical Trial Site Type 3 -c/o- Dr. Han Xu - Laboratories assigned by CRO / IRB / IORG
Bethesda, Maryland, United States, 20852 收起 <<
United States, New York
... 展开 >>
Albert Einstein Clinical Cancer Center
Bronx, New York, United States, 10461
New York Hospital Medical Center of Queens
Fresh Meadows, New York, United States, 11365
Saint Vincent Catholic Medical Center of New York
New York, New York, United States, 10011
NYU School of Medicine's Kaplan Comprehensive Cancer Center
New York, New York, United States, 10016
St. Luke's-Roosevelt Hospital Center - Roosevelt Division
New York, New York, United States, 10019
New York Weill Cornell Cancer Center at Cornell University
New York, New York, United States, 10021
Mount Sinai Medical Center, NY
New York, New York, United States, 10029
Herbert Irving Comprehensive Cancer Center at Columbia University
New York, New York, United States, 10032
New York Medical College
Valhalla, New York, United States, 10595
United States, Wisconsin
University of Wisconsin Comprehensive Cancer Center
Madison, Wisconsin, United States, 53792-3236 收起 <<
China, Beijing
... 展开 >> Beijing Cancer Hospital
Recruiting
Beijing, Beijing, China
Contact: zheng hong 010-88196102 zhhong306@hotmail.com
Principal Investigator: zheng hong
Cancer Hospital Chinese Academy of Medical Sciences
Recruiting
Beijing, Beijing, China
Contact: Wu Lingying 010-87788787 wulingying@csco.org.cn
Principal Investigator: wu lingying
China, Guangdong
The first affiliated hospital,sun yat-sen university
Recruiting
Guangzhou, Guangdong, China
Contact: Yao Shuzhong 020-87755766 ext 8185 yszlfy@163.com
Contact: Yao Shuzhong 02087755766 ext 02087755766 yszlfy@163.com
Principal Investigator: Yao Shuzhong
China, Hei Longjiang
the Affiliated Cancer Hospital of Harbin Medical University
Suspended
Harbin, Hei Longjiang, China
China, Hunan
Hunan Cancer Hospital
Recruiting
Changsha, Hunan, China
Contact: Zhang Keqiang 0731-89762695 ext 073189762695 1465217100@qq.com
Contact: Zhang Keqiang 073189762695 ext 073189762695 1465217100@qq.com
Principal Investigator: Zhang Keqiang
Wuhan Union Hospital
Recruiting
Wuhan, Hunan, China
Contact: Li Guiling 027-83691785 lgl6714@163.com
Principal Investigator: Li Guiling 收起 <<
United States, Tennessee
... 展开 >>
St. Jude Children's Research Hospital
Recruiting
Memphis, Tennessee, United States, 38105
Contact: Rachel C. Brennan, MD 866-278-5833 referralinfo@stjude.org
Principal Investigator: Rachel C. Brennan, MD 收起 <<
United States, Tennessee
... 展开 >>
St. Jude Children's Research Hospital
Recruiting
Memphis, Tennessee, United States, 38105
Contact: Wayne L. Furman, MD 866-278-5833 referralinfo@stjude.org
Principal Investigator: Wayne L. Furman, MD 收起 <<
Terminated(high rate of medull... 展开 >>ar aplasia with infectious troubles.) 收起 <<
-
France
... 展开 >> CRLC Val d'Aurelle
Montpellier, France, 34298
Hôpital HOTEL DIEU
Paris, France, 75004
Oncologie, Hôtel-Dieu, 1 place du parvis Notre-Dame
Paris, France, 75004
Centre Claudius Régaud
Toulouse, France, 31052 收起 <<
United States, Pennsylvania
... 展开 >>
Medical College of Pennsylvania Hospital
Philadelphia, Pennsylvania, United States, 19129
Medical College of Pennsylvania
Philadelphia, Pennsylvania, United States, 19129 收起 <<
United States, District of Col... 展开 >>umbia
Vincent T. Lombardi Cancer Research Center, Georgetown University
Washington, District of Columbia, United States, 20007 收起 <<
China, Shanxi
... 展开 >> Xi'an Jiaotong University College of Medicine
Recruiting
Xi'an, Shanxi, China, 710061
Contact: Zi Liu, M.D 086-18991232167 18991232167@189.cn
Contact: Tao Wang, M.D 086-18991232386 18991232386@189.cn
Sub-Investigator: Tao Wang, M.D 收起 <<
United States, Maryland
... 展开 >>
Medicine Invention Design, Inc. (MIDI) - c/o - MIDINC Clinical Investigator Working Site
North Bethesda, Maryland, United States, 20852 收起 <<
United States, Missouri
... 展开 >>
St. Louis University/Cardinal Glennon Childrens Medical Center
St. Louis, Missouri, United States, 63104
United States, Vermont
University of Vermont/Vermont Children's Hospital
Burlington, Vermont, United States, 05401 收起 <<
United Kingdom
... 展开 >> Charing Cross Hospital
London, England, United Kingdom, W6 8RF
Mount Vernon Hospital
Northwood, England, United Kingdom, HA6 2RN 收起 <<
Fallopian Tube Cancer
... 展开 >> Ovarian Cancer
Peritoneal Cavity Cancer 收起 <<
Phase 3
Completed
-
Canada, Alberta
... 展开 >>
Tom Baker Cancer Centre
Calgary, Alberta, Canada, T2N 4N2
Cross Cancer Institute
Edmonton, Alberta, Canada, T6G 1Z2
Canada, British Columbia
BCCA - Cancer Centre for the Southern Interior
Kelowna, British Columbia, Canada, V1Y 5L3
Lions Gate Hospital
North Vancouver, British Columbia, Canada, V7L 2L7
BCCA - Fraser Valley Cancer Centre
Surrey, British Columbia, Canada, V3V 1Z2
BCCA - Vancouver Cancer Centre
Vancouver, British Columbia, Canada, V5Z 4E6
Canada, Manitoba
CancerCare Manitoba
Winnipeg, Manitoba, Canada, R3E 0V9
Canada, New Brunswick
The Moncton Hospital
Moncton, New Brunswick, Canada, E1C 6Z8
Atlantic Health Sciences Corporation
Saint John, New Brunswick, Canada, E2L 4L2
Canada, Newfoundland and Labrador
Dr. H. Bliss Murphy Cancer Centre
St. John's, Newfoundland and Labrador, Canada, AIB 3V6
Canada, Nova Scotia
QEII Health Sciences Center
Halifax, Nova Scotia, Canada, B3H 1V7
Canada, Ontario
Juravinski Cancer Centre at Hamilton Health Sciences
Hamilton, Ontario, Canada, L8V 5C2
Cancer Centre of Southeastern Ontario at Kingston
Kingston, Ontario, Canada, K7L 5P9
Grand River Regional Cancer Centre
Kitchener, Ontario, Canada, N2G 1G3
London Regional Cancer Program
London, Ontario, Canada, N6A 4L6
Ottawa Health Research Institute - General Division
Ottawa, Ontario, Canada, K1H 8L6
Niagara Health System
St. Catharines, Ontario, Canada, L2R 7C6
Northeast Cancer Center Health Sciences
Sudbury, Ontario, Canada, P3E 5J1
Thunder Bay Regional Health Science Centre
Thunder Bay, Ontario, Canada, P7B 6V4
Univ. Health Network-Princess Margaret Hospital
Toronto, Ontario, Canada, M5G 2M9
Windsor Regional Cancer Centre
Windsor, Ontario, Canada, N8W 2X3
Canada, Prince Edward Island
PEI Cancer Treatment Centre,Queen Elizabeth Hospital
Charlottetown, Prince Edward Island, Canada, C1A 8T5
Canada, Quebec
CHUM - Hopital Notre-Dame
Montreal, Quebec, Canada, H2L 4M1
Hopital du Sacre-Coeur de Montreal
Montreal, Quebec, Canada, H4J 1C5
CHUQ-Pavillon Hotel-Dieu de Quebec
Quebec City, Quebec, Canada, G1R 2J6
Centre hospitalier universitaire de Sherbrooke
Sherbrooke, Quebec, Canada, J1H 5N4
Canada, Saskatchewan
Allan Blair Cancer Centre
Regina, Saskatchewan, Canada, S4T 7T1
Saskatoon Cancer Centre
Saskatoon, Saskatchewan, Canada, S7N 4H4 收起 <<
United States, Arizona
... 展开 >>
Mayo Clinic
Recruiting
Phoenix, Arizona, United States, 85054
Contact: Clinical Trials Referral Office 855-776-0015
Principal Investigator: John K. Camoriano
United States, Florida
Mayo Clinic
Recruiting
Jacksonville, Florida, United States, 32224
Contact: Clinical Trials Referral Office 855-776-0015
Principal Investigator: Gerardo Colon-Otero
United States, Minnesota
Mayo Clinic
Recruiting
Rochester, Minnesota, United States, 55905
Contact: Clinical Trials Referral Office 855-776-0015
Principal Investigator: Saravut J. Weroha 收起 <<
United States, California
... 展开 >>
Children's Hospital Los Angeles
Recruiting
Los Angeles, California, United States, 90027-0700
Contact: Araz Marachelian, MD 323-361-5687 amarachelian@chla.usc.edu
UCSF Helen Diller Family Comprehensive Cancer Center
Recruiting
San Francisco, California, United States, 94143
Contact: Katherine K. Matthay, MD 415-476-3831 matthayK@peds.ucsf.edu
United States, Colorado
Children Hospital of Colorado
Recruiting
Aurora, Colorado, United States, 80045
Contact: Margaret Macy, MD 720-777-8856 Margaret.macy@childrenscolorado.org
United States, Georgia
Children's Healthcare of Atlanta
Recruiting
Atlanta, Georgia, United States, 30322
Contact: Kelly Goldsmith, MD 404-785-0853 kgoldsmith@emory.edu
United States, Illinois
University of Chicago, Comer Children's Hospital
Recruiting
Chicago, Illinois, United States, 60637
Contact: Ami Desai, MD 773-843-3943 adesai12@peds.bsd.uchicago.edu
United States, Massachusetts
Childrens Hospital Boston, Dana-Farber Cancer Institute.
Recruiting
Boston, Massachusetts, United States, 02115
Contact: Suzanne Shusterman, MD 617-632-3725 suzanne_shusterman@dfci.harvard.edu
United States, Michigan
C.S Mott Children's Hospital
Recruiting
Ann Arbor, Michigan, United States, 48109
Contact: Rajen Mody, MD rmody@umich.edu
United States, North Carolina
University of North Carolina
Not yet recruiting
Chapel Hill, North Carolina, United States, 27599
Contact: Patrick Thompson, MD patom@email.unc.edu
United States, Ohio
Cincinnati Children's Hospital Medical Center
Recruiting
Cincinnati, Ohio, United States, 45229-3039
Contact: Brian Weiss, MD 513-636-9866 brian.weiss@chmcc.org
United States, Pennsylvania
Children's Hospital of Philadelphia
Recruiting
Philadelphia, Pennsylvania, United States, 19104-4318
Contact: Yael Mosse, MD 215-590-0965 mosse@chop.edu
United States, Texas
Cook Children's Healthcare System
Recruiting
Fort Worth, Texas, United States, 76104
Contact: Meaghan Granger, MD 682-885-4007 mgranger@cookchildrens.org
United States, Washington
Children's Hospital and Regional Medical Center - Seattle
Recruiting
Seattle, Washington, United States, 98105
Contact: Navin Pinto, MD 206-987-5783 navin.pinto@seattlechildrens.org
Canada, Ontario
Hospital for Sick Children
Not yet recruiting
Toronto, Ontario, Canada, M5G 1X8
Contact: Meredith Irwin, MD 416-813-7654 meredith.irwin@sickkids.ca
France
Institut Curie
Not yet recruiting
Paris, Cedex, France, 05
Contact: Gudrun Schleiermacher, MD 144324550 gudrun.schleiermacher@curie.fr
United Kingdom
Royal Marsden Hospital
Not yet recruiting
Sutton, Surrey, United Kingdom, SM25NG
Contact: Louis Chelser, MD 2087224204 Louis.Chesler@icr.ac.uk 收起 <<
United States, California
... 展开 >>
Rady Children's Hospital
Recruiting
San Diego, California, United States, 92123
Contact: Mehrzad Milburn 858-966-8155
Principal Investigator: William Roberts, MD
United States, Connecticut
Connecticut Children's Hospital
Recruiting
Hartford, Connecticut, United States, 06106
Contact: Sharon Huie-White 860-545-9337 shuie@connecticutchildrens.org
Principal Investigator: Michael Isakoff, MD
United States, Florida
Arnold Palmer Hospital for Children- MD Anderson
Recruiting
Orlando, Florida, United States, 32806
Contact: Michelle Pope, RN 321-841-8588
Principal Investigator: Don Eslin, MD
United States, Hawaii
Kapiolani Medical Center for Women and Children
Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Andrea Siu, MPH 808-535-7169 andrea.siu@kapiolani.org
Principal Investigator: Randal Wada, MD
United States, Massachusetts
Tufts Medical Center
Recruiting
Boston, Massachusetts, United States, 02111
Contact: Jennifer Truong 617-636-8885 jtruong@tuftsmedicalcenter.org
Principal Investigator: Michael Kelly, MD
United States, Michigan
Helen DeVos Children's Hospital
Recruiting
Grand Rapids, Michigan, United States, 49503
Contact: Shannon MacKeigan 616-267-1162 shannon.mackeigan@helendevoschildrens.org
Principal Investigator: Deanna Mitchell, MD
Principal Investigator: Giselle Sholler, MD
United States, Minnesota
Children's Hospital and Clinics on Minnesota
Recruiting
Minneapolis, Minnesota, United States, 55404
Contact: Courtney Haller 612-813-5913 courtney.haller@childrensmn.org
Principal Investigator: Jawhar Rawwas, MD
United States, Missouri
Children's Mercy Hospitals and Clinics
Recruiting
Kansas City, Missouri, United States, 64108
Contact: Sara Soliman, RN 816-855-1977 sjsoliman@cmh.edu
Principal Investigator: Kathleen Neville, MD
Cardinal Glennon Children's Medical Center
Recruiting
Saint Louis, Missouri, United States, 63104
Contact: Katherine Maxwell, RN 314-268-4000
Principal Investigator: William Ferguson, MD
United States, North Carolina
Levine Children's Hospital
Recruiting
Charlotte, North Carolina, United States, 28204
Contact: Elizabeth Arroyo-Green 980-442-2312 Elizabeth.ArroyoGreen@carolinashealthcare.org
Principal Investigator: Javier Oesterheld, MD
United States, Pennsylvania
Penn State Milton S. Hershey Medical Center and Children's Hospital
Recruiting
Hershey, Pennsylvania, United States, 17033
Contact: Suzanne Treadway streadway@hmc.psu.edu
Principal Investigator: Valerie Brown, MD
United States, South Carolina
Medical University of South Carolina
Recruiting
Charleston, South Carolina, United States, 29425
Contact: Jacqueline Kraveka, MD 843-792-2957
Principal Investigator: Jaqueline Kraveka, MD
United States, Texas
Children's Medical Center
Recruiting
Dallas, Texas, United States, 75235
Contact: Michelle Rivas 214-456-0004 michelle.rivas@childrens.com
Principal Investigator: Ted Laetsch, MD
Texas Children's Cancer and Hematology Centers
Recruiting
Houston, Texas, United States, 77030
Contact: Peter Zage, MD 832-824-4615 pezage@txch.org
Principal Investigator: Peter Zage, MD, PhD
United States, Utah
Primary Children's Hospital
Recruiting
Salt Lake City, Utah, United States, 84113
Contact: Lisa Smith 801-662-4710 Lisa.Smith@imail.org
Principal Investigator: Mark Fluchel, MD 收起 <<
United States, Indiana
... 展开 >>
Indiana University Cancer Center
Indianapolis, Indiana, United States, 46202-5289
United States, Iowa
John Stoddard Cancer Center at Iowa Methodist Medical Center
Des Moines, Iowa, United States, 50309
Mercy Cancer Center at Mercy Medical Center-Des Moines
Des Moines, Iowa, United States, 50314
Iowa Lutheran Hospital
Des Moines, Iowa, United States, 50316-2301
United States, Nebraska
Midlands Cancer Center at Midlands Community Hospital
Papillion, Nebraska, United States, 68128-4157
United States, New Mexico
MBCCOP - University of New Mexico HSC
Albuquerque, New Mexico, United States, 87131
United States, Pennsylvania
Penn State Cancer Institute at Milton S. Hershey Medical Center
Hershey, Pennsylvania, United States, 17033-0850
United States, Wisconsin
CCOP - St. Vincent Hospital Cancer Center, Green Bay
Green Bay, Wisconsin, United States, 54307-3453
Australia, New South Wales
Westmead Hospital
Westmead, New South Wales, Australia, 2145
Peru
Instituto de Enfermedades Neoplasicas
Lima, Peru, 34
Puerto Rico
San Juan City Hospital
San Juan, Puerto Rico, 00936-7344 收起 <<
United States, North Carolina
... 展开 >>
Southeastern Medical Oncology Center
Goldsboro, North Carolina, United States, 27534-9479
Comprehensive Cancer Center at Wake Forest University
Winston-Salem, North Carolina, United States, 27157-1082
United States, South Carolina
CCOP - Greenville
Greenville, South Carolina, United States, 29615
CCOP - Upstate Carolina
Spartanburg, South Carolina, United States, 29303
United States, Virginia
MBCCOP - Massey Cancer Center
Richmond, Virginia, United States, 23298-0037 收起 <<
United States, New York
... 展开 >>
NYU- Kaplan Comprehensive Cancer Center
New York, New York, United States, 10016
United States, Tennessee
The Sarah Cannon Cancer Center, Centennial Medical Center
Nashville, Tennessee, United States, 37203
United Kingdom
St Chad's Unit
Birmingham, United Kingdom, B18 7QH
Beatson Oncology Centre
Glasgow, United Kingdom, G11 6NT
Royal Surrey County Hospital
Guildford, Surrey, United Kingdom, GU2 7XX
Royal Marsden NHS Trust
London, United Kingdom, SW3 6JJ
Northern Centre for Cancer Research, Newcastle General Hospital
Newcastle-upon-Tyne, United Kingdom, NE4 6BE
Mount Vernon Hospital
Northwood, Middlesex, United Kingdom, HA6 2RN
CRC Department of Medical Oncology
Sutton Surrey, United Kingdom, SM2 5PT
Taunton & Somerset Hospital
Taunton, United Kingdom, TA1 5DA
Medical Oncology Unit, Torbay District General Hospital
Torquay, United Kingdom, TQ2 7AA 收起 <<
United States, Alabama
... 展开 >>
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294
United States, Arizona
Mayo Clinic in Arizona
Scottsdale, Arizona, United States, 85259
United States, Florida
Mayo Clinic in Florida
Jacksonville, Florida, United States, 32224-9980
United States, Illinois
Northwestern University
Chicago, Illinois, United States, 60611
United States, Iowa
Siouxland Hematology Oncology Associates
Sioux City, Iowa, United States, 51101
United States, Maryland
Johns Hopkins University/Sidney Kimmel Comprehensive Cancer Center
Baltimore, Maryland, United States, 21287
United States, Massachusetts
Tufts Medical Center
Boston, Massachusetts, United States, 02111
United States, Minnesota
Mayo Clinic
Rochester, Minnesota, United States, 55905
United States, Ohio
The Jewish Hospital
Cincinnati, Ohio, United States, 45236
United States, Pennsylvania
Geisinger Medical Center
Danville, Pennsylvania, United States, 17822-2001
Geisinger Medical Center-Cancer Center Hazleton
Hazleton, Pennsylvania, United States, 18201
Penn State Milton S Hershey Medical Center
Hershey, Pennsylvania, United States, 17033-0850
Lewistown Hospital
Lewistown, Pennsylvania, United States, 17044
Geisinger Medical Group
State College, Pennsylvania, United States, 16801
Mount Nittany Medical Center
State College, Pennsylvania, United States, 16803
Geisinger Wyoming Valley
Wilkes-Barre, Pennsylvania, United States, 18711
United States, Tennessee
Vanderbilt-Ingram Cancer Center
Nashville, Tennessee, United States, 37232
United States, Wisconsin
University of Wisconsin Hospital and Clinics
Madison, Wisconsin, United States, 53792
Froedtert and the Medical College of Wisconsin
Milwaukee, Wisconsin, United States, 53226
Israel
Rambam Medical Center
Haifa, Israel, 31096 收起 <<
Brain and Central Nervous Syst... 展开 >>em Tumors 收起 <<
Phase 1
Completed
-
United States, North Carolina
... 展开 >>
Duke Comprehensive Cancer Center
Durham, North Carolina, United States, 27710
United States, Tennessee
Saint Jude Children's Research Hospital
Memphis, Tennessee, United States, 38105-2794 收起 <<
Terminated(Lapatinib-topotecan... 展开 >> arm enrollment closed early per protocol amendment 2. Then enrollment into remaining arm terminated due to operational issues.) 收起 <<
United States, Ohio
... 展开 >>
Ireland Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer Center
Cleveland, Ohio, United States, 44106-5065 收起 <<
Terminated(Lapatinib-topotecan... 展开 >> arm enrollment closed early per protocol amendment 2. Then enrollment into remaining arm terminated due to operational issues.) 收起 <<
Small Cell Lung Cancer
... 展开 >> Ovarian Cancer
Solid Tumors 收起 <<
Phase 1
Active, not recruiting
December 2018
United States, Michigan
... 展开 >>
Barbara Ann Karmanos Cancer Center
Detroit, Michigan, United States, 48201
United States, Texas
South Texas Accelerated Research Therapeutics
San Antonio, Texas, United States, 78229 收起 <<
United States, California
... 展开 >>
UCSF Comprehensive Cancer Center
San Francisco, California, United States, 94143-0106
United States, Illinois
Children's Memorial Hospital - Chicago
Chicago, Illinois, United States, 60614
United States, Tennessee
St. Jude Children's Research Hospital
Memphis, Tennessee, United States, 38105
United States, Washington
Children's Hospital and Regional Medical Center - Seattle
Seattle, Washington, United States, 98105
Mary Bridge Children's Hospital and Health Center - Tacoma
Tacoma, Washington, United States, 98405
Australia, New South Wales
Westmead Hospital
Westmead, New South Wales, Australia, 2145 收起 <<
United States, Ohio
... 展开 >>
Ireland Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer Center
Cleveland, Ohio, United States, 44106-5065 收起 <<
Lung Cancer
M... 展开 >>etastatic Cancer
Ovarian Cancer
Unspecified Adult Solid Tumor, Protocol Specific 收起 <<
Early Phase 1
Terminated(Drugs unavailableun... 展开 >>able to make radioactive topotecan) 收起 <<
-
United States, Ohio
... 展开 >>
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center
Cleveland, Ohio, United States, 44106-5065 收起 <<
Fallopian Tube Cancer
... 展开 >> Ovarian Cancer
Primary Peritoneal Cavity Cancer 收起 <<
Phase 1
Terminated
-
United States, California
... 展开 >>
Community Hospital of Los Gatos
Los Gatos, California, United States, 95032
Chao Family Comprehensive Cancer Center
Orange, California, United States, 92868
Women's Cancer Center
Palo Alto, California, United States, 94304
United States, Illinois
University of Chicago Cancer Research Center
Chicago, Illinois, United States, 60637-1470
United States, Iowa
Holden Comprehensive Cancer Center at The University of Iowa
Iowa City, Iowa, United States, 52242-1009
United States, Pennsylvania
University of Pennsylvania Cancer Center
Philadelphia, Pennsylvania, United States, 19104-4283 收起 <<
United States, Washington
... 展开 >>
Fred Hutch/University of Washington Cancer Consortium
Recruiting
Seattle, Washington, United States, 98109
Contact: Pamela S. Becker 206-616-1589 pbecker@u.washington.edu
Principal Investigator: Pamela S. Becker 收起 <<
Platinum-resistant Recurrent O... 展开 >>varian Cancer 收起 <<
Phase 2
Recruiting
September 2022
Korea, Republic of
... 展开 >>
Seoul National University Hospital
Recruiting
Seoul, Korea, Republic of, 03080
Contact: Jae-Woen Kim, MD, Ph.D +82-2-2072-3511 kjwksh@snu.ac.kr
Principal Investigator: Jae-Woen Kim, MD, Ph.D
Yonsei University Health System, Severance Hospital
Recruiting
Seoul, Korea, Republic of, 03722
Contact: Jung-Yun Lee 82-2-2228-2230 jungyunlee@yuhs.ac
Samsung Medical Center
Recruiting
Seoul, Korea, Republic of, 06351
Contact: Byoung-Gie Kim, MD, Ph.D 82-2-3410-3513 bgkim@skku.edu
Principal Investigator: Byoung-Gie Kim, MD, Ph.D 收起 <<
China
... 展开 >> 307 Hospital of PLA
Beijin, China, 100071
Nanjing Bayi Hospital
Nanjing, China, 210002
Shanghai Cancer Hospital, Fudan University
Shanghai, China, 200032
Zhongshan Hospital, Fudan University
Shanghai, China, 200032
Taiwan
Chiayi Chang Gung Memorial Hosipital
Chiayi City, Taiwan
Kaohsiung Chang Gung Memorial Hospital
Kaohsiung, Taiwan
China Medical University Hosipital
Taichung, Taiwan
National Cheng Kung University Hospital
Tainan, Taiwan
Mackay Memorial Hosipital
Taipei City, Taiwan
National Taiwan University Hosipital
Taipei, Taiwan
Taipei Veterans General Hospital
Taipei, Taiwan
LinKou Chang Gung Memorial Hosipital
Taoyuan, Taiwan 收起 <<
United States, Maryland
... 展开 >>
National Institutes of Health Clinical Center
Recruiting
Bethesda, Maryland, United States, 20892
Contact: For more information at the NIH Clinical Center contact National Cancer Institute Referral Office 888-624-1937 收起 <<
United States, Arizona
... 展开 >>
Banner MD Anderson Cancer Center
Recruiting
Gilbert, Arizona, United States
United States, Connecticut
Yale Cancer Center
Recruiting
New Haven, Connecticut, United States
United States, Florida
Mayo Clinic
Recruiting
Jacksonville, Florida, United States
United States, Illinois
Loyola University Medical Center
Recruiting
Maywood, Illinois, United States
United States, Kansas
The University of Kansas Cancer Center
Recruiting
Westwood, Kansas, United States
United States, Minnesota
Mayo Clinic
Recruiting
Rochester, Minnesota, United States
United States, Missouri
Washington University School of Medicine
Recruiting
Saint Louis, Missouri, United States
United States, Nebraska
University of Nebraska Medical Center
Recruiting
Omaha, Nebraska, United States
United States, New York
Roswell Park Cancer Institute
Recruiting
Buffalo, New York, United States
Memorial Sloan Kettering Cancer Center
Recruiting
New York, New York, United States
Stony Brook University
Recruiting
Stony Brook, New York, United States
United States, Ohio
University Hospital of Cleveland Seidman Cancer Center
Recruiting
Cleveland, Ohio, United States
The Ohio State University Comprehensive Cancer Center
Recruiting
Columbus, Ohio, United States
United States, Texas
Baylor Charles A. Sammons Cancer Center
Recruiting
Dallas, Texas, United States
MD Anderson Cancer Center
Recruiting
Houston, Texas, United States
United States, Washington
Fred Hutchinson Cancer Research Center
Recruiting
Seattle, Washington, United States
United States, Wisconsin
Medical College of Wisconsin
Recruiting
Milwaukee, Wisconsin, United States
Canada, Ontario
University of Ottawa
Recruiting
Ottawa, Ontario, Canada 收起 <<
United States, Georgia
... 展开 >>
Medical College of Georgia
Augusta, Georgia, United States, 30912
United States, Massachusetts
Bidmc, Dfci, Mgh
Boston, Massachusetts, United States, 02215
United States, New York
Montefiore Medical Center
Bronx, New York, United States, 10461
Taiwan
National Taiwan University Hospital
Taipei, Taiwan 收起 <<
Argentina
... 展开 >> Hospital General de Agudos J. A. Penna ; Breast Pathology
Buenos Aires, Argentina, 1437
Instituto Ángel H. Roffo - Universidad de Buenos Aires
Buenos Aires, Argentina, B1650
Hospital Julio C. Perrando
Chaco, Argentina
Hospital General de Agudos Juan Antonio Fernandez
Ciudad Autonoma de Buenos Aires, Argentina, 1425
Hospital Pablo Soria
Jujuy, Argentina
Centro Oncologico Riojano Integral (CORI)
La Rioja, Argentina, F5300COE
Hospital Interzonal General De Agudos "Luisa C. de Gandulfo"
Lomas de Zamora, Argentina
Hospital Privado de Comunidad; Oncology
Mar Del Plata, Argentina, 7600
Hosp Provincial D. Centenarios; Oncology Dept
Rosario, Argentina, S2002KDS
CENICLAR
Rosario, Argentina
Policlínico regional de San Luis
San Luis, Argentina
Centro Medico San Roque
San Miguel de Tucuman, Argentina, T4000IAK 收起 <<
Ovarian Cancer
... 展开 >> Fallopian Tube Cancer
Primary Peritoneal Cancer 收起 <<
Phase 2
Completed
-
United States, Massachusetts
... 展开 >>
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States, 02115
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02215
Dana-Farber Cancer Institute
Boston, Massachusetts, United States, 02215 收起 <<
Germany
... 展开 >> Klinik für Onkologie und Haematologie
Frankfurt am Main, Germany, 60488
Klinikum Kassel Innere Medizin
Kassel, Germany, 34125
Italy
Azienda Ospedaliera "S. G. Moscati"
Avellino, AV, Italy, 83100
Istituto Nazionale Ricerca sul Cancro
Genova, GE, Italy, 16132
U.O. di Oncologia Medica
Palermo, PA, Italy, 90141
Ospedale Maggiore di Parma
Parma, PR, Italy, 43100
Azienda Ospedaliera San Camillo Forlanini
Rome, RM, Italy, 00151
Az. San. Ospedaliera Molinette S. Giovanni Battista di Torino
Torino, TO, Italy, 10126 收起 <<
United States, California
... 展开 >>
Rady Children's Hospital
Recruiting
San Diego, California, United States, 92123
Contact: Laura Conner 858-966-5983 LConner@rchsd.org
Principal Investigator: Peter Zage, MD
United States, Texas
Texas Children's Hospital
Recruiting
Houston, Texas, United States, 77030
Contact: Sarah Whittle, MD, BA 832-822-4242 sbwhittl@txch.org 收起 <<
China, Beijing
... 展开 >> Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Beijing, Beijing, China, 100021
China, Heilongjiang
The tumor hospital affiliated to Harbin medical university
Harbin, Heilongjiang, China, 150000
China, Sichuan
West China Hospital, Sichuan University
Chengdu, Sichuan, China, 610000 收起 <<
United States, Connecticut
... 展开 >>
Research Site
New Haven, Connecticut, United States
United States, Michigan
Research Site
Detroit, Michigan, United States
United States, New York
Research Site
New York City, New York, United States
United States, Pennsylvania
Research Site
Philadelphia, Pennsylvania, United States
United States, Texas
Research Site
Houston, Texas, United States
Research Site
San Antonio, Texas, United States 收起 <<
United States, New York
... 展开 >>
Memorial Sloan Kettering Cancer Center
New York, New York, United States, 10065
Weill Medical College of Cornell University
New York, New York, United States, 10065 收起 <<
United States, California
... 展开 >>
Children's Hospital of Los Angeles
Withdrawn
Los Angeles, California, United States, 90027
Lucille Packard Children's Hospital at Stanford University Medical Center
Recruiting
Palo Alto, California, United States, 94304
Contact: Sonia Partap, MD 650-723-0993 spartap@stanford.edu
Principal Investigator: Sonia Partap, MD
Rady Children's Hospital
Recruiting
San Diego, California, United States, 92123
Contact: John Crawford, MD, MS 858-576-1700 jcrawford@rchsd.org
Principal Investigator: John Crawford, MD, MS
United States, Colorado
Children's Hospital Colorado
Recruiting
Aurora, Colorado, United States, 80045
Contact: Kathleen Dorris, MD 720-777-6672 kathleen.dorris@childrenscolorado.org
Principal Investigator: Kathleen Dorris, MD
United States, District of Columbia
Children's National Medical Center
Recruiting
Washington, District of Columbia, United States, 20010
Contact: Lindsay B. Kilburn, MD 202-476-2800 lkilburn@childrensnational.org
Principal Investigator: Lindsay B. Kilburn, MD
United States, Florida
UF Cancer Center at Orlando Health
Recruiting
Orlando, Florida, United States, 32806
Contact: Amy A. Smith, MD 321-841-7246 amy.smith@orlandohealth.com
Principal Investigator: Amy A. Smith, MD
United States, Georgia
Children's Healthcare of Atlanta
Recruiting
Atlanta, Georgia, United States, 30322
Contact: Sindy Moon 404-785-1441 cindy.moon@choa.org
Contact: Jaclyn Smith 404-785-0692 jaclyn.smith@choa.org
Principal Investigator: Dolly Aguilera, MD
United States, Minnesota
Children's Hospital and Clinics of Minnesota
Recruiting
Minneapolis, Minnesota, United States, 55102
Contact: Anne Bendel, MD 651-220-6732 anne.bendel@childrensmn.org
Principal Investigator: Anne Bendel, MD
United States, Tennessee
St. Jude Children's Research Hospital
Recruiting
Memphis, Tennessee, United States, 38105
Contact: Tabatha E. Doyle, RN 901-595-2544 tabatha.doyle@stjude.org
Principal Investigator: Santhosh Upadhyaya, MD
United States, Texas
Texas Children's Hospital
Recruiting
Houston, Texas, United States, 77030
Contact: Patricia Baxter, MD 832-824-1000 pabaxter@txch.org
Principal Investigator: Patricia Baxter, MD
United States, Washington
Seattle Children's Hospital
Recruiting
Seattle, Washington, United States, 98105
Contact: Sarah Leary, MD 866-987-2000 sarah.leary@seattlechildrens.org
Principal Investigator: Sarah Leary, MD 收起 <<
Brain and Central Nervous Syst... 展开 >>em Tumors 收起 <<
Phase 2
Active, not recruiting
April 30, 2023
United States, California
... 展开 >>
Lucile Packard Children's Hospital at Stanford University Medical Center
Palo Alto, California, United States, 94304
Rady Children's Hospital
San Diego, California, United States, 92123
United States, Minnesota
Children's Hospitals and Clinics of Minnesota - St. Paul
Saint Paul, Minnesota, United States, 55102
United States, Tennessee
St. Jude Children's Research Hospital
Memphis, Tennessee, United States, 38105
United States, Texas
University of Texas Southwestern Medical Center at Dallas
Dallas, Texas, United States, 75390
Australia, Queensland
Lady Cilento Children's Hospital, Brisbane
Brisbane, Queensland, Australia, 4029 收起 <<
United States, Mississippi
... 展开 >>
Univeristy of Mississippi Medical Center
Recruiting
Jackson, Mississippi, United States, 39216
Contact: Kelly J Wilkinson, MD 888-815-2005 kjeanes@umc.edu
United States, West Virginia
Charleston Area Medical Center
Recruiting
Charleston, West Virginia, United States, 25326
Contact: Stephen Bush, MD 304-925-4200
Contact: Tina Garten, RN 304-388-9995 Tina.Garten@camc.org
Edwards Comprehensive Cancer Center - Cabell Huntington Hospital
Recruiting
Huntington, West Virginia, United States, 25705
Contact: Nadim Bou Zgheib, MD 304-399-6600 zgheib@marshall.edu
Contact: Barbara Payne, RN 304-399-6617 Barbara.Payne@chhi.org 收起 <<
Belgium
... 展开 >> 1230.18.32003 Boehringer Ingelheim Investigational Site
Brussel, Belgium
1230.18.32004 Boehringer Ingelheim Investigational Site
Edegem, Belgium
1230.18.32002 Boehringer Ingelheim Investigational Site
Gent, Belgium
1230.18.32001 Boehringer Ingelheim Investigational Site
Leuven, Belgium
France
1230.18.3321A Boehringer Ingelheim Investigational Site
Angers Cedex 9, France
1230.18.3307A Boehringer Ingelheim Investigational Site
Bordeaux cedex, France
1230.18.3301A Boehringer Ingelheim Investigational Site
Caen, France
1230.18.3322A Boehringer Ingelheim Investigational Site
Lille Cedex, France
1230.18.3313A Boehringer Ingelheim Investigational Site
Lyon, France
1230.18.3312A Boehringer Ingelheim Investigational Site
Nantes cedex 02, France
1230.18.3308A Boehringer Ingelheim Investigational Site
Nice cedex, France
1230.18.3314A Boehringer Ingelheim Investigational Site
Paris Cedex 20, France
1230.18.3302A Boehringer Ingelheim Investigational Site
Paris, France
1230.18.3309A Boehringer Ingelheim Investigational Site
Pierre-Bénite cedex, France
1230.18.3305A Boehringer Ingelheim Investigational Site
Reims cedex, France
1230.18.3320A Boehringer Ingelheim Investigational Site
Saint-Brieuc cedex, France
1230.18.3311A Boehringer Ingelheim Investigational Site
Strasbourg, France
1230.18.3310A Boehringer Ingelheim Investigational Site
Toulouse Cedex 9, France
1230.18.3315A Boehringer Ingelheim Investigational Site
Vandoeuvre les Nancy cedex, France
Slovakia
1230.18.42101 Boehringer Ingelheim Investigational Site
Bratislava, Slovakia
1230.18.42103 Boehringer Ingelheim Investigational Site
Poprad, Slovakia
Spain
1230.18.34006 Boehringer Ingelheim Investigational Site
Badalona, Spain
1230.18.34001 Boehringer Ingelheim Investigational Site
Barcelona, Spain
1230.18.34005 Boehringer Ingelheim Investigational Site
Barcelona, Spain
1230.18.34007 Boehringer Ingelheim Investigational Site
Girona, Spain
1230.18.34004 Boehringer Ingelheim Investigational Site
L'Hospitalet de Llobregat, Spain
1230.18.34002 Boehringer Ingelheim Investigational Site
Madrid, Spain
1230.18.34003 Boehringer Ingelheim Investigational Site
Madrid, Spain
Sweden
1230.18.46005 Boehringer Ingelheim Investigational Site
Linköping, Sweden
1230.18.46001 Boehringer Ingelheim Investigational Site
Stockholm, Sweden
1230.18.46003 Boehringer Ingelheim Investigational Site
Uppsala, Sweden 收起 <<
United States, Arizona
... 展开 >>
Mayo Clinic
Recruiting
Phoenix, Arizona, United States, 85054
Contact: Clinical Trials Referral Office 855-776-0015
Principal Investigator: John K. Camoriano, M.D.
United States, Florida
Mayo Clinic
Recruiting
Jacksonville, Florida, United States, 32224
Contact: Clinical Trials Referral Office 855-776-0015
Principal Investigator: Gerardo Colon-Otero, M.D.
United States, Minnesota
Mayo Clinic
Recruiting
Rochester, Minnesota, United States, 55905
Contact: Clinical Trials Referral Office 855-776-0015
Principal Investigator: Evanthia Galanis, M.D.
Sub-Investigator: Matthew S. Block, M.D. 收起 <<
Mexico
... 展开 >> Instituto Nacional de Cancerologia
Recruiting
Mexico City, Distrito Federal, Mexico, 14080
Principal Investigator: Lucely Cetina, MD 收起 <<
Unspecified Childhood Solid Tu... 展开 >>mor, Protocol Specific 收起 <<
Phase 1
Unknown
-
United States, Washington
... 展开 >>
Children's Hospital and Regional Medical Center - Seattle
Seattle, Washington, United States, 98105
Fred Hutchinson Cancer Research Center
Seattle, Washington, United States, 98109-1024 收起 <<
United States, Arizona
... 展开 >>
Premiere Oncology
Scottsdale, Arizona, United States, 85258
United States, California
Premiere Oncology
Santa Monica, California, United States, 90404
United States, Texas
Audie Murphy Veterans Memorial Hospital (VA)
San Antonio, Texas, United States, 78229
CTRC at the UT Health Science Center at San Antonio
San Antonio, Texas, United States, 78229
South Texas Accelerated Research Therapy (START)
San Antonio, Texas, United States, 78229 收起 <<
United Kingdom
... 展开 >> Beatson West of Scotland Cancer Centre
Recruiting
Glasgow, Lanarkshire, United Kingdom, G12 0YN
Contact: Ros Glasspool
Principal Investigator: Ros Glasspool
Sub-Investigator: Iain McNeish
Ninewells Hospital
Recruiting
Dundee, Tayside, United Kingdom
Principal Investigator: Michelle Ferguson
Clatterbridge Cancer Centre
Recruiting
Liverpool, Wirral, United Kingdom
Principal Investigator: Rosemary Lord
Belfast City Hospital (Northern Ireland Cancer Centre)
Recruiting
Belfast, United Kingdom
Principal Investigator: Sarah McKenna
Bristol Heamatology and Cancer Centre
Recruiting
Bristol, United Kingdom
Principal Investigator: Axel Walther
Velindre Hospital
Recruiting
Cardiff, United Kingdom
Principal Investigator: Rachel Jones
Kent & Canterbury Hospital
Recruiting
Kent, United Kingdom
Principal Investigator: Justin Waters
Queen Elizabeth Queen Mother Hospital
Recruiting
Kent, United Kingdom
Principal Investigator: Justin Waters
William Harvey Hospital
Recruiting
Kent, United Kingdom
Principal Investigator: Justin Waters
St James Hospital
Recruiting
Leeds, United Kingdom
Principal Investigator: Geoff Hall
Guy's Hosital
Recruiting
London, United Kingdom
Principal Investigator: Ana Montes
Royal Marsden Hospital
Recruiting
London, United Kingdom
Principal Investigator: Susannah Bannerjee
St Bartholomew's Hospital
Not yet recruiting
London, United Kingdom
Principal Investigator: Melanie Powell
University College London Hospital
Not yet recruiting
London, United Kingdom
Principal Investigator: Jonathan Ledermann
The Christie Hospital
Recruiting
Manchester, United Kingdom
Principal Investigator: Andrew Clamp
Great Western Hospital
Recruiting
Swindon, United Kingdom
Principal Investigator: Omar Khan
Musgrove Park Hospital
Recruiting
Taunton, United Kingdom
Principal Investigator: Clare Barlow 收起 <<
Carcinoma of Unknown Primary
... 展开 >> Lung Cancer 收起 <<
Phase 2
Completed
-
United States, Maryland
... 展开 >>
Johns Hopkins Oncology Center
Baltimore, Maryland, United States, 21231
United States, Pennsylvania
Fox Chase Cancer Center
Philadelphia, Pennsylvania, United States, 19111 收起 <<
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