Gatifloxacin is a fluoroquinolone antibiotic that inhibits bacterial type II topoisomerases (IC50=13.8μg/ml for S. aureus topoisomerase IV; IC50=0.109μg/ml for E. coli DNA gyrase) but shows low inhibition against HeLa cell topoisomerase II (IC50=265μg/ml)[3]. Gatifloxacin (subcutaneous injection; 100 mg/kg; 3 times a day; 30 days) significantly decreases the number of lesions in mouse footpad with Nocardia brasiliensis[4].
China
... 展开 >> Beijing Children's Hospital of Capital Medical University
Recruiting
Beijing, China
Contact: Adong Shen, Master 13370115087 shenad16@hotmail.com 收起 <<
United States, Kentucky
... 展开 >>
University of Louisville
Recruiting
Louisville, Kentucky, United States, 40202
Contact: Julio A Ramirez, MD 502-852-1148 jarami01@louisville.edu
Contact: David Seligson, MD 502-852-0923 d0seli01@louisville.edu
Sub-Investigator: Forest Arnold, DO
Sub-Investigator: Timothy Wiemkwn, PhD
Sub-Investigator: Robert Kelley, PhD
Sub-Investigator: James Summersgill, PhD
Sub-Investigator: Ruth Carrico, PhD
Sub-Investigator: Julie Harting, PharmD
Sub-Investigator: Paula Peyrani, MD
Principal Investigator: David Seligson, MD
Sub-Investigator: Craig Roberts, MD
Principal Investigator: Julio Ramirez, MD 收起 <<
China
... 展开 >> Beijing Children's Hospital of Capital Medical University
Recruiting
Beijing, China
Contact: Adong Shen, Master 13370115087 shenad16@hotmail.com 收起 <<
United States, Kentucky
... 展开 >>
University of Louisville
Recruiting
Louisville, Kentucky, United States, 40202
Contact: Julio A Ramirez, MD 502-852-1148 jarami01@louisville.edu
Contact: David Seligson, MD 502-852-0923 d0seli01@louisville.edu
Sub-Investigator: Forest Arnold, DO
Sub-Investigator: Timothy Wiemkwn, PhD
Sub-Investigator: Robert Kelley, PhD
Sub-Investigator: James Summersgill, PhD
Sub-Investigator: Ruth Carrico, PhD
Sub-Investigator: Julie Harting, PharmD
Sub-Investigator: Paula Peyrani, MD
Principal Investigator: David Seligson, MD
Sub-Investigator: Craig Roberts, MD
Principal Investigator: Julio Ramirez, MD 收起 <<
United States, South Carolina
... 展开 >>
Carolina Eyecare Physicians, LLC
Recruiting
Mount Pleasant, South Carolina, United States, 29464
Contact: Helga P Sandoval, MD, MSCR 843-881-3937 helga.sandoval@carolinaeyecare.com
Principal Investigator: Kerry D Solomon, MD
Sub-Investigator: Jefrrey F Hood, OD 收起 <<
Benin
... 展开 >> Programme National de Lutte contre la Tuberculose
Recruiting
Cotonou, Benin
Contact: Martin Gninafon, MD + 229 33 15 33 pnt@intnet.bj
Principal Investigator: Martin Gninafon, MD
Guinea
Service Pneumo-Phtisiologie, CHU Ignace Deen
Recruiting
Conakry, Guinea
Contact: Oumou Y Sow, MD +224 41 20 58 prsow@kassa.sotelgui.net.gn
Principal Investigator: Oumou Sow, MD
Kenya
Kenya Medical Research Institute
Recruiting
Nairobi, Kenya
Contact: Joseph Odhiambo, MD + 254 02 71 30 08 jodhiambo@nairobi.mimcom.net
Principal Investigator: Joseph Odhiambo, MD
Senegal
Programme National de Lutte contre la Tuberculose
Recruiting
Dakar, Senegal
Contact: Cheikh Seck, MD + 221 824.90.09 cheikbaf@yahoo.fr
Principal Investigator: Cheikh Seck, MD
South Africa
Medical Research Council
Recruiting
Durban, KwaZulu, South Africa
Contact: Roxana Rustomjee, MD +27 31 207 16 75 Roxana.rustomjee@mrc.ac.za
Principal Investigator: Roxana Rustomjee, MD 收起 <<
United States, California
... 展开 >>
San Francisco General Hospital - Pulmonary and Critical Care Medicine
San Francisco, California, United States, 94110-3518
Brazil
Universidade Federal do Espirito Santo - Duke Hubert-Yeargan Center
Vitória, Espírito Santo, Brazil, 29040-091 收起 <<
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