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4-Isopropylantipyrine
4-异丙基安替比林 /4-Isopropylantipyrine
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货号：A871713
同义名：
异丙安替比林
/ Isopropylphenazone;Propyphenazone
4-Isopropylantipyrine 是一种吡唑酮类衍生物，具有抗炎、镇痛和退烧作用。Propyphenazone 类似物可作为前药，并作为选择性环氧合酶-2（COX-2）抑制剂。
4-Isopropylantipyrine 化学结构
4-Isopropylantipyrine 3D分子结构
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4-Isopropylantipyrine 纯度/质量文件 产品仅供科研
货号：A871713
标准纯度：
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4-Isopropylantipyrine 质控信息
4-Isopropylantipyrine 生物活性
描述
Propyphenazone is a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, Propyphenazone-based analogues as prodrugs and selective cyclooxygenase-2 inhibitors[3] [4] [5] [6]
4-Isopropylantipyrine 参考文献
[1] Sucheta, Paliwal M, et al. Synthesis and Biological Evaluation of Mutual Prodrugs of Carboxylic Group Containing Some Non-Steroidal Anti-Inflammatory Drugs and Propyphenazone. Curr Drug Deliv. 2017 Feb 13.
[2] Radwan MF, Dalby KN, et al. Propyphenazone-based analogues as prodrugs and selective cyclooxygenase-2 inhibitors. ACS Med Chem Lett. 2014 Jun 23;5(9):983-8.
[3] Burdan F. Formation of the knee joint after prenatal propyphenazone (isopropylantipyrine) administration. Cells Tissues Organs. 2002;171(2-3):145-51
[4] Burdan F. Developmental effects of propyphenazone in analgesic and antipyretic combination with caffeine or paracetamol. Hum Exp Toxicol. 2004 May;23(5):235-44
[5] Boerlin V, Maeglin B, Hägler W, Kuhn M, Nüesch E. Analgesic activity of propyphenazone in patients with pain following oral surgery. Eur J Clin Pharmacol. 1986;31(2):127-31
[6] Volz M, Kellner HM. Kinetics and metabolism of pyrazolones (propyphenazone, aminopyrine and dipyrone). Br J Clin Pharmacol. 1980 Oct;10 Suppl 2(Suppl 2):299S-308S
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4-Isopropylantipyrine 实验方案
计算器
摩尔计算器
总药量计算器
工作液计算器
存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
4.34mL
0.87mL
0.43mL
21.71mL
4.34mL
2.17mL
43.42mL
8.68mL
4.34mL
4-Isopropylantipyrine 技术信息
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