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阿糖腺苷 /Vidarabine {[allProObj[0].p_purity_real_show]}

货号：A153495 同义名： Vira-A;NSC 404241

Vidarabine is an antiviral drug effects by interfering with the synthesis of viral DNA, which is used in treatment of herpes simplex and varicella zoster viruses.

Vidarabine 化学结构
CAS号：5536-17-4

Vidarabine 3D分子结构
CAS号：5536-17-4

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Vidarabine 纯度/质量文件产品仅供科研

货号：A153495 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

全球学术期刊中引用的产品: • Nat. Biomed. Eng., 2024, 8, 1412-1424. Ambeed. [ A538667 , A631746 ]; • JMC, 2024. Ambeed. [ A833302 , A475501 , A341986 , A356070 ]; • BMC Cancer, 2024, 24(1): 1415. Ambeed. [ A809692 , A209020 ]; • J. Am. Soc. Mass Spectrom., 2024, 35(12): 3192-3202. Ambeed. [ A166127 , A902473 , A753371 , A961334 , A292945 , A230770 , A300620 , A1114580 , A1159765 , A206238 ]; • PloS One, 2024, 19(11): e0308060. Ambeed. [ A302917 ]; 更多 >

DNA 亚型比较

产品名称	DNA synthesis ↓ ↑	helicase ↓ ↑	RdRp ↓ ↑	ribonucleotide reductase ↓ ↑	tRNA synthetase ↓ ↑	YB-1 ↓ ↑	其他靶点	纯度
Fexinidazole	✔							98%
Daptomycin	✔							98%
Blasticidin S·HCl	✔							98%
Metronidazole	✔							98%
Daunorubicin HCl	+++ DNA synthesis, Ki: 20 nM							98%
Triglycidyl isocyanurate	✔						p53	98+%
Nedaplatin	✔							99%+
Bendamustine	✔							98+%
Trifluridine	✔							98%
Robinetin	✔							99%+
Carboplatin	✔							99%
Cidofovir	✔							99%
Cisplatin	✔							99%
Cytarabine	++++ DNA synthesis, IC50: 16 nM							98%
Acelarin	++++ DNA synthesis, EC50: 0.2 nM							99%+
Oxaliplatin	✔							98%
YK-4-279		✔						99%+
ML216		+ BLM^full-length, IC50: 2.98 μM BLM^636-1298, IC50: 0.97 μM						99%+
RK-33		✔						98%
Brr2-IN-3		✔						99%+
Phen-DC3 Trifluoromethanesulfonate		✔						98%
Favipiravir			✔					97%
Suramin sodium salt			++ RdRp, IC50: 0.26 μM					99%+
Clofarabine				++ Ribonucleotide reductase, IC50: 65 nM				97%
Didox				✔				98%
(E)-3-AP				✔				97%
Halofuginone					+++ prolyl-tRNA synthetase, Ki: 18.3nM			99%+
BC-LI-0186					+++ Leucyl-tRNA synthetase, Kd: 42.1 nM Leucyl-tRNA synthetase, IC50: 46.11 nM			98%
SU056						+ YB-1, IC50: 1.73 μM		98%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

Vidarabine 生物活性

描述	Vidarabine (Ara-A) is an antiviral agent particularly effective against herpes simplex and varicella zoster viruses^[1].^[2]. Vidarabine demonstrates inhibitory activity with IC50 values of 9.3 μg/ml for HSV-1 and 11.3 μg/ml for HSV-2, indicating its potency against these strains^[2]. Additionally, Vidarabine shows anti-orthopoxvirus activity, broadening its antiviral scope^[3].
体外研究	Extracted from Streptomyces antibioticus, Vidarabine is a nucleoside antibiotic that not only has antineoplastic properties but also a broad spectrum of activity against DNA viruses in cell cultures. It is particularly noted for its significant antiviral efficacy against infections by various viruses including herpes viruses, vaccinia virus, and varicella zoster virus^[1].

Vidarabine 参考文献

[1]Whitley, R., et al., Vidarabine: a preliminary review of its pharmacological properties and therapeutic use. Drugs, 1980. 20(4): p. 267-82.

[2]Suzuki M, et al. Synergistic antiviral activity of acyclovir and vidarabine against herpes simplex virus types 1 and 2 and varicella-zoster virus. Antiviral Res. 2006;72(2):157-161.

[3]Donald F Smee, et al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57(1-2):41-52.

Vidarabine 实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

3.74mL

0.75mL

0.37mL

18.71mL

3.74mL

1.87mL

37.42mL

7.48mL

3.74mL

Vidarabine 技术信息

CAS号	5536-17-4
分子式	C₁₀H₁₃N₅O₄
分子量	267.241

别名	Vira-A;NSC 404241;9-beta-Arabinofuranosyladenine;Arabinofuranosyladenine;NSC 247519;Arabinosyladenine;9-β-D-Arabinofuranosyladenine;Adenine Arabinoside;Ara-A
运输	蓝冰

存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Sealed in dry,Store in freezer, under -20°C

溶解度

DMSO: 50 mg/mL(187.1 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

动物实验配方

阿糖腺苷 /Vidarabine {[allProObj[0].p_purity_real_show]}

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阿糖腺苷 /Vidarabine {[allProObj[0].p_purity_real_show]}

Vidarabine 纯度/质量文件 产品仅供科研

全球学术期刊中引用的产品

Vidarabine 质控信息

Vidarabine 生物活性

Vidarabine 参考文献

Vidarabine 实验方案

Vidarabine 技术信息

最近浏览的产品

大规格询价

摩尔计算器

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总药量计算器

工作液计算器

细胞研究

临床研究

确认信息

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Vidarabine 纯度/质量文件产品仅供科研