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甾体半胱氨酸 /Sterigmatocystine {[allProObj[0].p_purity_real_show]}

货号:A384145 同义名: NSC 201423;NSC 204985 Ambeed 开学季,买赠积分,赢豪礼

Sterigmatocystin is a mycotoxin produced by common mold strains. It induces sister chromatid exchanges in bone marrow cells of mice and has been shown to induce lung and liver tumors in vitro, as well as necrosis of the liver. Sterigmatocystin may function to inhibit of p21, and thereby DNA synthesis.

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Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Sterigmatocystine 化学结构 CAS号:10048-13-2
Sterigmatocystine 化学结构
CAS号:10048-13-2
Sterigmatocystine 3D分子结构
CAS号:10048-13-2
Sterigmatocystine 化学结构 CAS号:10048-13-2
Sterigmatocystine 3D分子结构 CAS号:10048-13-2
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Sterigmatocystine 纯度/质量文件 产品仅供科研

货号:A384145 标准纯度: {[allProObj[0].p_purity_real_show]}
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产品名称 DNA synthesis helicase RdRp ribonucleotide reductase tRNA synthetase YB-1 其他靶点 纯度
Fexinidazole {[allProObj[0].p_purity_real_show]}
Daptomycin {[allProObj[0].p_purity_real_show]}
Blasticidin S·HCl {[allProObj[0].p_purity_real_show]}
Metronidazole {[allProObj[0].p_purity_real_show]}
Daunorubicin HCl +++

DNA synthesis, Ki: 20 nM

{[allProObj[0].p_purity_real_show]}
Triglycidyl isocyanurate p53 {[allProObj[0].p_purity_real_show]}
Nedaplatin {[allProObj[0].p_purity_real_show]}
Bendamustine {[allProObj[0].p_purity_real_show]}
Trifluridine {[allProObj[0].p_purity_real_show]}
Robinetin {[allProObj[0].p_purity_real_show]}
Carboplatin {[allProObj[0].p_purity_real_show]}
Cidofovir {[allProObj[0].p_purity_real_show]}
Cisplatin {[allProObj[0].p_purity_real_show]}
Cytarabine ++++

DNA synthesis, IC50: 16 nM

{[allProObj[0].p_purity_real_show]}
Acelarin ++++

DNA synthesis, EC50: 0.2 nM

{[allProObj[0].p_purity_real_show]}
Oxaliplatin {[allProObj[0].p_purity_real_show]}
YK-4-279 {[allProObj[0].p_purity_real_show]}
ML216 +

BLM636-1298, IC50: 0.97 μM

BLMfull-length, IC50: 2.98 μM

{[allProObj[0].p_purity_real_show]}
RK-33 {[allProObj[0].p_purity_real_show]}
Brr2-IN-3 {[allProObj[0].p_purity_real_show]}
Phen-DC3 Trifluoromethanesulfonate {[allProObj[0].p_purity_real_show]}
Favipiravir {[allProObj[0].p_purity_real_show]}
Suramin sodium salt ++

RdRp, IC50: 0.26 μM

{[allProObj[0].p_purity_real_show]}
Clofarabine ++

Ribonucleotide reductase, IC50: 65 nM

{[allProObj[0].p_purity_real_show]}
Didox {[allProObj[0].p_purity_real_show]}
(E)-3-AP {[allProObj[0].p_purity_real_show]}
Halofuginone +++

prolyl-tRNA synthetase, Ki: 18.3nM

{[allProObj[0].p_purity_real_show]}
BC-LI-0186 +++

Leucyl-tRNA synthetase, IC50: 46.11 nM

Leucyl-tRNA synthetase, Kd: 42.1 nM

{[allProObj[0].p_purity_real_show]}
SU056 +

YB-1, IC50: 1.73 μM

{[allProObj[0].p_purity_real_show]}
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。

Sterigmatocystine 生物活性

描述 Sterigmatocystin is a mycotoxin produced by common mold strains. It induces sister chromatid exchanges in bone marrow cells of mice and has been shown to induce lung and liver tumors in vitro, as well as necrosis of the liver. Sterigmatocystin may function to inhibit of p21, and thereby DNA synthesis.

Sterigmatocystine 参考文献

[1]Curry PT, Reed RN, et al. Induction of sister-chromatid exchanges in vivo in mice by the mycotoxins sterigmatocystin and griseofulvin. Mutat Res. 1984 Aug-Sep;137(2-3):111-5.

[2]Terao K. Massive and single cell necrosis in the rat liver induced by aflatoxin B1 and sterigmatocystin. Acta Pathol Jpn. 1973 Aug;23(3):647-53.

Sterigmatocystine 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.08mL

0.62mL

0.31mL

15.42mL

3.08mL

1.54mL

30.84mL

6.17mL

3.08mL

Sterigmatocystine 技术信息

CAS号10048-13-2
分子式C18H12O6
分子量 324.284
别名 NSC 201423;NSC 204985;Sterigmatocystin
运输蓝冰
存储条件

粉末 2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度

DMSO: 25 mg/mL(77.09 mM),配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

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