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Sterigmatocystine

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Chemical Structure| 10048-13-2 同义名 : NSC 201423;NSC 204985;Sterigmatocystin
CAS号 : 10048-13-2
货号 : A384145
分子式 : C18H12O6
纯度 : 99+%
分子量 : 324.28
MDL号 : MFCD00005084
存储条件：

粉末 2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 25 mg/mL(77.09 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Sterigmatocystin is a mycotoxin produced by common mold strains. It induces sister chromatid exchanges in bone marrow cells of mice and has been shown to induce lung and liver tumors in vitro, as well as necrosis of the liver. Sterigmatocystin may function to inhibit of p21, and thereby DNA synthesis.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.08mL

0.62mL

0.31mL

15.42mL

3.08mL

1.54mL

30.84mL

6.17mL

3.08mL
参考文献

[1]Curry PT, Reed RN, et al. Induction of sister-chromatid exchanges in vivo in mice by the mycotoxins sterigmatocystin and griseofulvin. Mutat Res. 1984 Aug-Sep;137(2-3):111-5.

[2]Terao K. Massive and single cell necrosis in the rat liver induced by aflatoxin B1 and sterigmatocystin. Acta Pathol Jpn. 1973 Aug;23(3):647-53.