Triapine | 3-AP | Ribonucleotide Reductase Inhibitor | AmBeed-信号通路专用抑制剂

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2-[(3-氨基吡啶-2-基)亚甲基]氨基硫脲 /Triapine {[allProObj[0].p_purity_real_show]}

货号：A348408 同义名： 3-AP;PAN-811

Triapine is a ribonucleotide reductase inhibitor and a CDK inhibtor.

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There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type	HazMat fee for 500 gram (Estimated)
Excepted Quantity	USD 0.00
Limited Quantity	USD 15-60
Inaccessible (Haz class 6.1), Domestic	USD 80+
Inaccessible (Haz class 6.1), International	USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic	USD 100+
Accessible (Haz class 3, 4, 5 or 8), International	USD 200+

Triapine 化学结构
CAS号：143621-35-6

Triapine 3D分子结构
CAS号：143621-35-6

规格	价格	会员价	库存	数量
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Triapine 纯度/质量文件产品仅供科研

货号：A348408 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

全球学术期刊中引用的产品: • Cell, 2024, 101755. Ambeed. [ A399663 ]; • EMBO J., 2024. Ambeed. [ A295334 ]; • JMC, 2024, 67(20): 18265-18289. Ambeed. [ A538667 , A341145 , A117430 , A172297 ]; • JMC, 2024. Ambeed. [ A210558 , A1518164 ]; • Cell Death Discov., 2024, 10, 436. Ambeed. [ A384235 ]; 更多 >

DNA 亚型比较

产品名称	DNA synthesis ↓ ↑	helicase ↓ ↑	RdRp ↓ ↑	ribonucleotide reductase ↓ ↑	tRNA synthetase ↓ ↑	YB-1 ↓ ↑	其他靶点	纯度
Fexinidazole	✔							98%
Daptomycin	✔							98%
Blasticidin S·HCl	✔							98%
Metronidazole	✔							98%
Daunorubicin HCl	+++ DNA synthesis, Ki: 20 nM							98%
Triglycidyl isocyanurate	✔						p53	98+%
Nedaplatin	✔							99%+
Bendamustine	✔							98+%
Trifluridine	✔							98%
Robinetin	✔							99%+
Carboplatin	✔							99%
Cidofovir	✔							99%
Cisplatin	✔							99%
Cytarabine	++++ DNA synthesis, IC50: 16 nM							98%
Acelarin	++++ DNA synthesis, EC50: 0.2 nM							99%+
Oxaliplatin	✔							98%
YK-4-279		✔						99%+
ML216		+ BLM^636-1298, IC50: 0.97 μM BLM^full-length, IC50: 2.98 μM						99%+
RK-33		✔						98%
Brr2-IN-3		✔						99%+
Phen-DC3 Trifluoromethanesulfonate		✔						98%
Favipiravir			✔					97%
Suramin sodium salt			++ RdRp, IC50: 0.26 μM					99%+
Clofarabine				++ Ribonucleotide reductase, IC50: 65 nM				97%
Didox				✔				98%
(E)-3-AP				✔				97%
Halofuginone					+++ prolyl-tRNA synthetase, Ki: 18.3nM			99%+
BC-LI-0186					+++ Leucyl-tRNA synthetase, IC50: 46.11 nM Leucyl-tRNA synthetase, Kd: 42.1 nM			98%
SU056						+ YB-1, IC50: 1.73 μM		98%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

Triapine 生物活性

描述

Ribonucleotide reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides, which is essential for maintaining a balanced pool of deoxyribonucleotides for DNA synthesis and repair. Triapine is a potent inhibitor of ribonucleotide reductase. In vitro, it fully blocked ischemic neurotoxicity at 0.5 μM with an EC₅₀ value of 0.35 μM. It also inhibited hypoxic toxicity with an EC₅₀ value of around 0.75 μM. Triapine at 0.63 μM and 0.45 μM completely inhibited HGH-induced mitochondrial dysfunction and LDH release with EC₅₀ values of 0.2 - 0.35 μM. In neuron cells, treatment with 10 μM Triapine decreased 100 μM glutamate-induced cell death by 89%. In cortical neurons, the addition of 10 μM Triapine 24h prior to and during the experiment reduced neurotoxicity of 1 μM staurosporine by 47%Jiang ZG, Lebowitz MS, Ghanbari HA. Neuroprotective activity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (PAN-811), a cancer therapeutic agent. CNS Drug Rev. 2006 Spring;12(1):77-90. doi: 10.1111/j.1527-3458.2006.00077.x. PMID: 16834759; PMCID: PMC6741723.https://pubmed.ncbi.nlm.nih.gov/16834759/. In mice bearing M109 lung carcinoma, intravenous injection of triapine either once daily (24 mg/kg) or twice daily (6 mg/kg) for 5 consecutive days significantly inhibited the tumor growth. The administration of triapine (5 mg/kg, twice daily, 5 consecutive days) also inhibited the DNA synthesis in the bone marrow and intestinal mucosa^[5].

Triapine 细胞研究

细胞系	浓度	检测类型	检测时间	活动说明	数据源
HCT116 cells	4 μM	Function assay	24 h	Induction of ROS generation in human HCT116 cells expressing wild type p53 at 4 uM after 24 hrs by spectrophotometry	24900837
human HCT116 cells		Cytotoxicity assay	96 h	Dark cytotoxicity against human HCT116 cells expressing wild type p53 after 96 hrs by MTT assay, IC50=1.226 μM	24900837
KB-3-1 cells		Cytotoxicity assay	72 h	Cytotoxicity against human P-gp-negative KB-3-1 cells after 72 hrs by MTT assay, IC50=1.4 μM	19397322
KBV1 cells		Cytotoxicity assay	72 h	Cytotoxicity against human P-glycoprotein-expressing KBV1 cells after 72 hrs by MTT assay, IC50=5.9 μM	19397322

Triapine 动物研究

Dose	Mice: 10 mg/kg^[3] (i.p.); 20 mg/kg^[4] (s.c.)
Administration	i.p., s.c.

Triapine 临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT02644122	-		Terminated(Slow enrollment)	-	-
NCT02644122	Metastatic Squamous Neck Cance... 展开 >>r With Occult Primary Squamous Cell Carcinoma 收起 <<	Phase 2	Terminated(Slow enrollment)	-	United States, California ... 展开 >> UC San Diego Moores Cancer Center La Jolla, California, United States, 92093 收起 <<
NCT00024323	Unspecified Adult Solid Tumor,... 展开 >> Protocol Specific 收起 <<	Phase 1	Completed	-	United States, Arizona ... 展开 >> Arizona Clinical Research Center Tucson, Arizona, United States, 85712 United States, Connecticut Yale Comprehensive Cancer Center New Haven, Connecticut, United States, 06520-8028 收起 <<

Triapine 参考文献

[1]Jiang ZG, Lebowitz MS, Ghanbari HA. Neuroprotective activity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (PAN-811), a cancer therapeutic agent. CNS Drug Rev. 2006 Spring;12(1):77-90.

[2]Finch RA, Liu M, et al. Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity. Biochem Pharmacol. 2000 Apr 15;59(8):983-91.

[3]Lin ZP, Zhu YL, et al. Combination of triapine, olaparib, and cediranib suppresses progression of BRCA-wild type and PARP inhibitor-resistant epithelial ovarian cancer. PLoS One. 2018 Nov 16;13(11):e0207399.

[4]Dai L, Chen J, et al. Ribonucleotide Reductase Inhibitor 3-AP Induces Oncogenic Virus Infected Cell Death and Represses Tumor Growth. J Cancer. 2018 Oct 31;9(23):4503-4509.

[5]10692563

Triapine 实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

5.12mL

1.02mL

0.51mL

25.61mL

5.12mL

2.56mL

51.22mL

10.24mL

5.12mL

Triapine 技术信息

CAS号	143621-35-6
分子式	C₇H₉N₅S
分子量	195.245

别名	3-AP;PAN-811;NSC663249. PAN-811;AIDS179996;3Apct;NSC 663249;3-Aminopyridine-2-Carboxyaldehyde Thiosemicarbazone;OCX191
运输	蓝冰

存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

溶解度

DMSO: 45 mg/mL(230.48 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

动物实验配方

5%DMSO+40%PEG300+5%Tween80+50%water 1.25 mg/mL

临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT02644122	-		Terminated(Slow enrollment)	-	-
NCT02644122	Metastatic Squamous Neck Cance... 展开 >>r With Occult Primary Squamous Cell Carcinoma 收起 <<	Phase 2	Terminated(Slow enrollment)	-	United States, California ... 展开 >> UC San Diego Moores Cancer Center La Jolla, California, United States, 92093 收起 <<
NCT00024323	Unspecified Adult Solid Tumor,... 展开 >> Protocol Specific 收起 <<	Phase 1	Completed	-	United States, Arizona ... 展开 >> Arizona Clinical Research Center Tucson, Arizona, United States, 85712 United States, Connecticut Yale Comprehensive Cancer Center New Haven, Connecticut, United States, 06520-8028 收起 <<
NCT01095731	Aneurysmal Subarachnoid Hemorr... 展开 >>hage 收起 <<	Phase 2	Completed	-	United States, Florida ... 展开 >> University of Florida Gainesville, Florida, United States, 32611 United States, New York Columbia University Medical Center New York, New York, United States, 10032 United States, Washington University of Washington Seattle, Washington, United States, 96104 收起 <<
NCT00355654	Infant Health... 展开 >>y 收起 <<	Phase 3	Completed	-	-
NCT00016874	Unspecified Adult Solid Tumor,... 展开 >> Protocol Specific 收起 <<	Phase 1	Completed	-	United States, New York ... 展开 >> Albert Einstein Comprehensive Cancer Center Bronx, New York, United States, 10461 New York Presbyterian Hospital - Cornell Campus New York, New York, United States, 10021 收起 <<
NCT00064064	Lung Cancer	Phase 2	Completed	-	United States, Illinois ... 展开 >> University of Chicago Cancer Research Center Chicago, Illinois, United States, 60637-1470 United States, Minnesota University of Minnesota Cancer Center Minneapolis, Minnesota, United States, 55455 United States, Tennessee Sarah Cannon Cancer Center at Centennial Medical Center Nashville, Tennessee, United States, 37203 United States, Texas University of Texas - MD Anderson Cancer Center Houston, Texas, United States, 77030-4009 Netherlands University Medical Center Nijmegen Nijmegen, Netherlands, NL-6500 HB 收起 <<
NCT00004213	Unspecified Adult Solid Tumor,... 展开 >> Protocol Specific 收起 <<	Phase 1	Completed	-	United States, Arizona ... 展开 >> Arizona Clinical Research Center Tucson, Arizona, United States, 85712 United States, Connecticut Yale Comprehensive Cancer Center New Haven, Connecticut, United States, 06520-8028 收起 <<
NCT00077558	Leukemia Myel... 展开 >>odysplastic Syndromes Myelodysplastic/Myeloproliferative Diseases 收起 <<	Phase 1	Completed	-	United States, Georgia ... 展开 >> Blood and Marrow Transplant Group of Georgia Atlanta, Georgia, United States, 30342-4777 United States, Maryland Greenebaum Cancer Center at University of Maryland Medical Center Baltimore, Maryland, United States, 21201 Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231 United States, Texas M.D. Anderson Cancer Center at University of Texas Houston, Texas, United States, 77030-4095 收起 <<
NCT00064090	Leukemia Myel... 展开 >>odysplastic Syndromes Myelodysplastic/Myeloproliferative Neoplasms 收起 <<	Phase 1	Completed	-	United States, Texas ... 展开 >> University of Texas - MD Anderson Cancer Center Houston, Texas, United States, 77030-4095 收起 <<
NCT00054015	Prostate Cancer	Phase 2	Completed	-	United States, California ... 展开 >> UCSF Comprehensive Cancer Center San Francisco, California, United States, 94115 United States, Florida H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida, United States, 33612-9497 收起 <<
NCT00064051	Pancreatic Cancer	Phase 2	Completed	-	United States, Illinois ... 展开 >> University of Chicago Cancer Research Center Chicago, Illinois, United States, 60637-1470 United States, Indiana Indiana Oncology Hematology Consultants Indianapolis, Indiana, United States, 46202 United States, Minnesota University of Minnesota Cancer Center Minneapolis, Minnesota, United States, 55455 United States, Tennessee Sarah Cannon Cancer Center at Centennial Medical Center Nashville, Tennessee, United States, 37203 Belgium Universitair Ziekenhuis Gent Ghent, Belgium, B-9000 United Kingdom Christie Hospital N.H.S. Trust Manchester, England, United Kingdom, M20 4BX Royal Marsden NHS Foundation Trust - Surrey Sutton, England, United Kingdom, SM2 5PT 收起 <<
NCT00075660	Kidney Cancer	Phase 2	Completed	-	Canada, Alberta ... 展开 >> Cross Cancer Institute Edmonton, Alberta, Canada, T6G 1Z2 Canada, British Columbia British Columbia Cancer Agency Vancouver, British Columbia, Canada, V5Z 4E6 Canada, Manitoba CancerCare Manitoba Winnipeg, Manitoba, Canada, R3E 0V9 Canada, Ontario Margaret and Charles Juravinski Cancer Centre Hamilton, Ontario, Canada, L8V 5C2 Cancer Care Ontario-London Regional Cancer Centre London, Ontario, Canada, N6A 4L6 Toronto Sunnybrook Regional Cancer Centre Toronto, Ontario, Canada, M4N 3M5 Toronto General Hospital Toronto, Ontario, Canada, M5G 2C4 Canada, Quebec Centre Hospitalier de l'Universite de Montreal Montreal, Quebec, Canada, H2L-4M1 收起 <<
NCT00006218	Unspecified Adult Solid Tumor,... 展开 >> Protocol Specific 收起 <<	Phase 1	Completed	-	United States, New York ... 展开 >> Albert Einstein Comprehensive Cancer Center Bronx, New York, United States, 10461 收起 <<
NCT00077415	Lung Cancer	Phase 2	Completed	-	Australia, New South Wales ... 展开 >> Sydney Cancer Centre at Royal Prince Alfred Hospital Sydney, New South Wales, Australia, 2050 Australia, Western Australia Sir Charles Gairdner Hospital - Perth Perth, Western Australia, Australia, 6009 Hong Kong Prince of Wales Hospital Shatin, New Territories, Hong Kong Korea, Republic of Yonsei Cancer Center at Yonsei University Medical Center Seoul, Korea, Republic of, 120-752 Singapore Cancer Institute at National University Hospital Singapore, Singapore, 119074 National University of Singapore Singapore, Singapore, 119260 National Cancer Centre - Singapore Singapore, Singapore, 169610 Johns Hopkins Singapore International Medical Centre Singapore, Singapore, 308433 收起 <<
NCT00084877	Unspecified Adult Solid Tumor,... 展开 >> Protocol Specific 收起 <<	Phase 1	Completed	-	United States, Wisconsin ... 展开 >> University of Wisconsin Hospital and Clinics Madison, Wisconsin, United States, 53792 收起 <<
NCT00381550	Accelerated Phase Chronic Myel... 展开 >>ogenous Leukemia Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative Blastic Phase Chronic Myelogenous Leukemia Chronic Eosinophilic Leukemia Chronic Myelomonocytic Leukemia Essential Thrombocythemia Philadelphia Chromosome Negative Chronic Myelogenous Leukemia Polycythemia Vera Primary Myelofibrosis Relapsing Chronic Myelogenous Leukemia 收起 <<	Phase 2	Completed	-	United States, Maryland ... 展开 >> Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore, Maryland, United States, 21287 收起 <<
NCT00079014	Unspecified Adult Solid Tumor,... 展开 >> Protocol Specific 收起 <<	Phase 1	Completed	-	United States, Wisconsin ... 展开 >> University of Wisconsin Hospital and Clinics Madison, Wisconsin, United States, 53792 收起 <<
NCT00081276	Primary Peritoneal Cavity Canc... 展开 >>er Recurrent Ovarian Epithelial Cancer Stage III Ovarian Epithelial Cancer Stage IV Ovarian Epithelial Cancer 收起 <<	Phase 2	Completed	-	United States, Pennsylvania ... 展开 >> Gynecologic Oncology Group Philadelphia, Pennsylvania, United States, 19103 收起 <<
NCT00078975	Pancreatic Cancer	Phase 2	Completed	-	Canada, Ontario ... 展开 >> Margaret and Charles Juravinski Cancer Centre Hamilton, Ontario, Canada, L8V 5C2 London Regional Cancer Program at London Health Sciences Centre London, Ontario, Canada, N6A 4L6 Ottawa Hospital Regional Cancer Centre - General Campus Ottawa, Ontario, Canada, K1H 1C4 Princess Margaret Hospital Toronto, Ontario, Canada, M5G 2M9 收起 <<
NCT00381550	-		Completed	-	-
NCT00941070	Recurrent Cervical Cancer ... 展开 >> Recurrent Vaginal Cancer Stage IB Cervical Cancer Stage II Vaginal Cancer Stage IIA Cervical Cancer Stage IIB Cervical Cancer Stage III Cervical Cancer Stage III Vaginal Cancer Stage IVA Cervical Cancer Stage IVA Vaginal Cancer Stage IVB Cervical Cancer Stage IVB Vaginal Cancer Therapy-related Toxicity 收起 <<	Phase 2	Completed	-	United States, Ohio ... 展开 >> Case Western Reserve University Cleveland, Ohio, United States, 44106 收起 <<
NCT00077545	Adenocarcinoma of the Esophagu... 展开 >>s Recurrent Esophageal Cancer Stage IV Esophageal Cancer 收起 <<	Phase 2	Completed	-	United States, Illinois ... 展开 >> University of Chicago Comprehensive Cancer Center Chicago, Illinois, United States, 60637-1470 收起 <<
NCT00941070	-		Completed	-	-
NCT00077181	Accelerated Phase Chronic Myel... 展开 >>ogenous Leukemia Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) Adult Acute Myeloid Leukemia With t(15;17)(q22;q12) Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) Blastic Phase Chronic Myelogenous Leukemia Recurrent Adult Acute Lymphoblastic Leukemia Recurrent Adult Acute Myeloid Leukemia Relapsing Chronic Myelogenous Leukemia Secondary Acute Myeloid Leukemia 收起 <<	Phase 1	Completed	-	United States, Illinois ... 展开 >> University of Chicago Comprehensive Cancer Center Chicago, Illinois, United States, 60637-1470 收起 <<
NCT02466971	Cervical Adenocarcinoma ... 展开 >> Cervical Adenosquamous Carcinoma Cervical Squamous Cell Carcinoma, Not Otherwise Specified Stage IB2 Cervical Cancer AJCC v6 and v7 Stage II Cervical Cancer AJCC v7 Stage II Vaginal Cancer AJCC v6 and v7 Stage IIA Cervical Cancer AJCC v7 Stage IIB Cervical Cancer AJCC v6 and v7 Stage III Vaginal Cancer AJCC v6 and v7 Stage IIIB Cervical Cancer AJCC v6 and v7 Stage IVA Cervical Cancer AJCC v6 and v7 Stage IVA Vaginal Cancer AJCC v6 and v7 Vaginal Adenocarcinoma Vaginal Adenosquamous Carcinoma Vaginal Squamous Cell Carcinoma, Not Otherwise Specified 收起 <<	Phase 2	Recruiting	September 30, 2018	-
NCT00085371	Acinar Cell Adenocarcinoma of ... 展开 >>the Pancreas Duct Cell Adenocarcinoma of the Pancreas Recurrent Pancreatic Cancer Stage III Pancreatic Cancer Stage IV Pancreatic Cancer 收起 <<	Phase 2	Completed	-	United States, Minnesota ... 展开 >> Mayo Clinic Rochester, Minnesota, United States, 55905 收起 <<
NCT00288093	Pancreatic Adenocarcinoma ... 展开 >> Stage III Pancreatic Cancer AJCC v6 and v7 收起 <<	Phase 1	Completed	-	United States, Ohio ... 展开 >> Ohio State University Comprehensive Cancer Center Columbus, Ohio, United States, 43210 收起 <<
NCT00095888	Male Breast Cancer ... 展开 >> Recurrent Breast Cancer Stage IV Breast Cancer 收起 <<	Phase 2	Terminated(Administratively co... 展开 >>mplete.) 收起 <<	-	United States, Minnesota ... 展开 >> Mayo Clinic Rochester, Minnesota, United States, 55905 收起 <<
NCT00335998	Recurrent Cervical Cancer ... 展开 >> Recurrent Ovarian Epithelial Cancer Recurrent Vaginal Cancer Recurrent Vulvar Cancer Stage III Vaginal Cancer Stage IIIA Cervical Cancer Stage IIIA Ovarian Epithelial Cancer Stage IIIA Vulvar Cancer Stage IIIB Cervical Cancer Stage IIIB Ovarian Epithelial Cancer Stage IIIB Vulvar Cancer Stage IIIC Ovarian Epithelial Cancer Stage IIIC Vulvar Cancer Stage IV Ovarian Epithelial Cancer Stage IVA Cervical Cancer Stage IVA Vaginal Cancer Stage IVB Cervical Cancer Stage IVB Vaginal Cancer 收起 <<	Phase 1	Completed	-	United States, Ohio ... 展开 >> Case Western Reserve University Cleveland, Ohio, United States, 44106 收起 <<
NCT00293345	Anaplastic Large Cell Lymphoma... 展开 >> Angioimmunoblastic T-cell Lymphoma Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue Intraocular Lymphoma Nodal Marginal Zone B-cell Lymphoma Primary Central Nervous System Hodgkin Lymphoma Primary Central Nervous System Non-Hodgkin Lymphoma Recurrent Adult Burkitt Lymphoma Recurrent Adult Diffuse Large Cell Lymphoma Recurrent Adult Diffuse Mixed Cell Lymphoma Recurrent Adult Diffuse Small Cleaved Cell Lymphoma Recurrent Adult Hodgkin Lymphoma Recurrent Adult Immunoblastic Large Cell Lymphoma Recurrent Adult Lymphoblastic Lymphoma Recurrent Adult T-cell Leukemia/Lymphoma Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma Recurrent Grade 1 Follicular Lymphoma Recurrent Grade 2 Follicular Lymphoma Recurrent Grade 3 Follicular Lymphoma Recurrent Mantle Cell Lymphoma Recurrent Marginal Zone Lymphoma Recurrent Mycosis Fungoides/Sezary Syndrome Recurrent Small Lymphocytic Lymphoma Small Intestine Lymphoma Splenic Marginal Zone Lymphoma Stage III Adult Burkitt Lymphoma Stage III Adult Diffuse Large Cell Lymphoma Stage III Adult Diffuse Mixed Cell Lymphoma Stage III Adult Diffuse Small Cleaved Cell Lymphoma Stage III Adult Hodgkin Lymphoma Stage III Adult Immunoblastic Large Cell Lymphoma Stage III Adult Lymphoblastic Lymphoma Stage III Adult T-cell Leukemia/Lymphoma Stage III Cutaneous T-cell Non-Hodgkin Lymphoma Stage III Grade 1 Follicular Lymphoma Stage III Grade 2 Follicular Lymphoma Stage III Grade 3 Follicular Lymphoma Stage III Mantle Cell Lymphoma Stage III Marginal Zone Lymphoma Stage III Mycosis Fungoides/Sezary Syndrome Stage III Small Lymphocytic Lymphoma Stage IV Adult Burkitt Lymphoma Stage IV Adult Diffuse Large Cell Lymphoma Stage IV Adult Diffuse Mixed Cell Lymphoma Stage IV Adult Diffuse Small Cleaved Cell Lymphoma Stage IV Adult Hodgkin Lymphoma Stage IV Adult Immunoblastic Large Cell Lymphoma Stage IV Adult Lymphoblastic Lymphoma Stage IV Adult T-cell Leukemia/Lymphoma Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma Stage IV Grade 1 Follicular Lymphoma Stage IV Grade 2 Follicular Lymphoma Stage IV Grade 3 Follicular Lymphoma Stage IV Mantle Cell Lymphoma Stage IV Marginal Zone Lymphoma Stage IV Mycosis Fungoides/Sezary Syndrome Stage IV Small Lymphocytic Lymphoma Unspecified Adult Solid Tumor, Protocol Specific Waldenström Macroglobulinemia 收起 <<	Phase 1	Completed	-	United States, Ohio ... 展开 >> Ohio State University Medical Center Columbus, Ohio, United States, 43210 收起 <<
NCT02595879	Cervical Adenocarcinoma ... 展开 >> Cervical Adenosquamous Carcinoma Cervical Squamous Cell Carcinoma, Not Otherwise Specified Stage IB Vulvar Cancer AJCC v7 Stage IB2 Cervical Cancer AJCC v6 and v7 Stage II Vulvar Cancer AJCC v7 Stage IIA1 Cervical Cancer AJCC v7 Stage IIA2 Cervical Cancer AJCC v7 Stage IIB Cervical Cancer AJCC v6 and v7 Stage IIIA Cervical Cancer AJCC v6 and v7 Stage IIIA Vulvar Cancer AJCC v7 Stage IIIB Cervical Cancer AJCC v6 and v7 Stage IIIB Vulvar Cancer AJCC v7 Stage IIIC Vulvar Cancer AJCC v7 Stage IVA Cervical Cancer AJCC v6 and v7 Stage IVA Vulvar Cancer AJCC v7 Vulvar Adenocarcinoma Vulvar Squamous Cell Carcinoma 收起 <<	Phase 1	Suspended(Drug Supply Issues)	-	United States, Pennsylvania ... 展开 >> University of Pittsburgh Cancer Institute (UPCI) Pittsburgh, Pennsylvania, United States, 15232 United States, Virginia University of Virginia Cancer Center Charlottesville, Virginia, United States, 22908 收起 <<
NCT00077350	Recurrent Non-small Cell Lung ... 展开 >>Cancer 收起 <<	Phase 2	Completed	-	United States, Massachusetts ... 展开 >> Eastern Cooperative Oncology Group Boston, Massachusetts, United States, 02215 收起 <<
NCT00075504	Stage II Gallbladder Cancer ... 展开 >> Stage IIIA Gallbladder Cancer Stage IIIB Gallbladder Cancer Stage IVA Gallbladder Cancer Stage IVB Gallbladder Cancer 收起 <<	Phase 2	Completed	-	United States, New York ... 展开 >> Montefiore Medical Center Bronx, New York, United States, 10467-2490 收起 <<
NCT00390052	Unspecified Adult Solid Tumor,... 展开 >> Protocol Specific 收起 <<	Phase 1	Completed	-	United States, California ... 展开 >> City of Hope Duarte, California, United States, 91010 收起 <<
NCT00075504	-		Completed	-	-

2-[(3-氨基吡啶-2-基)亚甲基]氨基硫脲 /Triapine {[allProObj[0].p_purity_real_show]}

Triapine 纯度/质量文件产品仅供科研

全球学术期刊中引用的产品

Triapine 质控信息

Triapine 生物活性

Triapine 细胞研究

Triapine 动物研究

Triapine 临床研究

Triapine 参考文献

Triapine 实验方案

Triapine 技术信息

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2-[(3-氨基吡啶-2-基)亚甲基]氨基硫脲 /Triapine {[allProObj[0].p_purity_real_show]}

Triapine 纯度/质量文件 产品仅供科研

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