货号:A290622 同义名: MK-639;L735524
Indinavir sulfate is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability.
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产品名称 | MMP ↓ ↑ | 其他靶点 | 纯度 | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Marimastat |
+++
MMP-14, IC50: 3 nM MMP-7, IC50: 16 nM |
98% | |||||||||||||||||
Ilomastat |
++++
MMP-26, Ki: 0.36 nM MMP-2, Ki: 0.1 nM |
99%+ | |||||||||||||||||
SB-3CT |
+
MMP-9, Ki: 600 nM MMP-2, Ki: 13.9 nM |
99%+ | |||||||||||||||||
Doxycycline | ✔ | 98% | |||||||||||||||||
NSC 405020 | ✔ | 98% | |||||||||||||||||
Batimastat |
+++
MMP-7, IC50: 4 nM MMP-1, IC50: 3 nM |
99%+ | |||||||||||||||||
Nobiletin | ✔ | 98% | |||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
产品名称 | HIV Protease ↓ ↑ | HIV-1 caspid ↓ ↑ | 其他靶点 | 纯度 | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dextran sulfate sodium, mw 40,000 | ✔ | M.W 40000 | |||||||||||||||||
Vicriviroc maleate | ✔ | 98+% | |||||||||||||||||
Rosamultin | ✔ | 97% | |||||||||||||||||
Darunavir | ✔ | 98% | |||||||||||||||||
Lopinavir |
++++
HIV protease, Ki: 1.3 pM |
99+% | |||||||||||||||||
Chloroquine | ✔ | Autophagy | 95% | ||||||||||||||||
Amprenavir |
+
HIV protease, IC50: 14.6 ng/mL |
PXR | 99%+ | ||||||||||||||||
NBD-556 | ✔ | 99%+ | |||||||||||||||||
Nelfinavir Mesylate |
+++
HIV protease, Ki: 2 nM |
99%+ | |||||||||||||||||
Atazanavir Sulfate | ✔ | 98% | |||||||||||||||||
Limonin | ✔ | 98% | |||||||||||||||||
Saquinavir |
++
HIV proteinase, IC50: 2.7 nM |
98% | |||||||||||||||||
Ritonavir | ✔ | 98% | |||||||||||||||||
Azvudine | ✔ | 98% | |||||||||||||||||
Lenacapavir |
++++
HIV-1 capsid, EC50: 0.1 nM |
97% | |||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
描述 | Indinavir sulfate is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability. |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT00002440 | HIV Infections | Phase 2 | Completed | - | United States, California ... 展开 >> UCSD Treatment Ctr San Diego, California, United States, 921036329 United States, Connecticut Yale U / New Haven Med Ctr / AIDS Clinical Trials Unit New Haven, Connecticut, United States, 065102483 United States, Missouri Kansas City AIDS Research Consortium Kansas City, Missouri, United States, 64111 United States, New York NYU Med Ctr / Dept of Medicine / AIDS Clinical Trial New York, New York, United States, 10016 United States, North Carolina Carolinas Med Ctr Charlotte, North Carolina, United States, 28232 United States, Ohio Case Western Reserve Univ / AIDS Clinical Trials Unit Cleveland, Ohio, United States, 44106 United States, Pennsylvania Univ of Pittsburgh Med Ctr Pittsburgh, Pennsylvania, United States, 15213 United States, Tennessee Vanderbilt Univ Med Ctr Nashville, Tennessee, United States, 372321302 收起 << |
NCT00006154 | HIV Infections | Phase 3 | Completed | - | Canada, British Columbia ... 展开 >> Viridae Clinical Sciences / University of British Columbia Vancouver, British Columbia, Canada Canada, Quebec Centre de traitment d'immunodeficience Montreal, Quebec, Canada Centre Hospitalier de la Universite de Montreal (CHUM) Montreal, Quebec, Canada Institut Thoracique de Montreal Montreal, Quebec, Canada 收起 << |
NCT00000923 | HIV Infections | Not Applicable | Completed | - | United States, Alabama ... 展开 >> Alabama Therapeutics CRS Birmingham, Alabama, United States, 35294 United States, California USC CRS Los Angeles, California, United States, 900331079 Harbor-UCLA Med. Ctr. CRS Torrance, California, United States, 90502 United States, Hawaii Univ. of Hawaii at Manoa, Leahi Hosp. Honolulu, Hawaii, United States, 96816 United States, Iowa Univ. of Iowa Healthcare, Div. of Infectious Diseases Iowa City, Iowa, United States, 52242 United States, Louisiana Tulane Univ. A1701 CRS New Orleans, Louisiana, United States, 70112 United States, Missouri St. Louis ConnectCare, Infectious Diseases Clinic St Louis, Missouri, United States, 63112 Washington U CRS St. Louis, Missouri, United States United States, New York Mt. Sinai Med. Ctr. A0404 CRS New York, New York, United States, 10029 United States, Ohio Case CRS Cleveland, Ohio, United States, 44106 The Ohio State Univ. AIDS CRS Columbus, Ohio, United States, 432101228 United States, Washington University of Washington AIDS CRS Seattle, Washington, United States, 98104 收起 << |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
1.40mL 0.28mL 0.14mL |
7.02mL 1.40mL 0.70mL |
14.05mL 2.81mL 1.40mL |
CAS号 | 157810-81-6 |
分子式 | C36H49N5O8S |
分子量 | 711.868 |
别名 | MK-639;L735524;Indinavir (sulfate);Crixivan |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 粉末 Inert atmosphere,2-8°C |
溶解度 |
DMSO: 105 mg/mL(147.5 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO H2O: 50 mg/mL(70.24 mM),配合低频超声助溶 |
动物实验配方 |