Saquinavir | Ro 31-8959 | HIV Protease Inhibitor | AmBeed-信号通路专用抑制剂

产品名称	HIV Protease ↓ ↑	HIV-1 caspid ↓ ↑	其他靶点	纯度
Dextran sulfate sodium, mw 40,000	✔			M.W 40000
Vicriviroc maleate	✔			95%
Rosamultin	✔			97%
Darunavir	✔			98%
Lopinavir	++++ HIV protease, Ki: 1.3 pM			99+%
Chloroquine	✔		Autophagy	95%
Amprenavir	+ HIV protease, IC50: 14.6 ng/mL		PXR	99%+
NBD-556	✔			99%+
Nelfinavir Mesylate	+++ HIV protease, Ki: 2 nM			99%+
Atazanavir Sulfate	✔			98%
Limonin	✔			98%
Saquinavir	++ HIV proteinase, IC50: 2.7 nM			98%
Ritonavir	✔			98%
Azvudine	✔			98%
Lenacapavir		++++ HIV-1 capsid, EC50: 0.1 nM		97%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT01936870	-		Completed	-	-
NCT01936870	-		Completed	-	-
NCT02556268	HIV-DDI	Phase 1	Completed	-	United States, Florida ... 展开 >> Orlando, Florida, United States, 32803 United States, Massachusetts Boston, Massachusetts, United States, 02118 收起 <<
NCT00197145	-		Terminated	-	-
NCT00000914	HIV Infections	Not Applicable	Completed	-	United States, California ... 展开 >> Community Consortium / UCSF San Francisco, California, United States, 94110 United States, Colorado Denver CPCRA / Denver Public Hlth Denver, Colorado, United States, 802044507 United States, District of Columbia Washington Reg AIDS Prog / Dept of Infect Dis Washington, District of Columbia, United States, 20422 United States, Georgia AIDS Research Consortium of Atlanta Atlanta, Georgia, United States, 303081962 United States, Illinois AIDS Research Alliance - Chicago Chicago, Illinois, United States, 60657 United States, Louisiana Louisiana Comm AIDS Rsch Prog / Tulane Univ Med New Orleans, Louisiana, United States, 70112 United States, Michigan Wayne State Univ - WSU/DMC / Univ Hlth Ctr Detroit, Michigan, United States, 48201 Henry Ford Hosp Detroit, Michigan, United States, 48202 United States, New Jersey Southern New Jersey AIDS Cln Trials / Dept of Med Camden, New Jersey, United States, 08103 North Jersey Community Research Initiative Newark, New Jersey, United States, 071032842 United States, New Mexico Partners in Research / New Mexico Albuquerque, New Mexico, United States, 87131 United States, New York Harlem AIDS Treatment Grp / Harlem Hosp Ctr New York, New York, United States, 10037 United States, Oregon The Research and Education Group Portland, Oregon, United States, 97210 United States, Pennsylvania Philadelphia FIGHT Philadelphia, Pennsylvania, United States, 19107 United States, Virginia Richmond AIDS Consortium / Div of Infect Diseases Richmond, Virginia, United States, 232980049 收起 <<
NCT00850395	-		Completed	-	-
NCT01252940	HIV-1 Infection	Phase 3	Completed	-	-
NCT02616783	HIV-1 Infection	Phase 3	Completed	-	Belgium ... 展开 >> CHU Saint-Pierre University Hospital Brussels, Belgium University Hospital Gent Ghent, Belgium France CHU - Groupe Saint-Andre Bordeaux, France CHU de Dijon Dijon, France Hopital Europeen Marseille Marseille, France C.H.U. de Nantes Nantes, France C.H.U. de NICE Nice, France Hopital Saint Louis Paris cedex 10, France Hopital Saint Antoine Paris cedex 12, France CHU Hotel Dieu Paris, France Hopital Necker les Enfants Malades Paris, France Hopital Haut-Leveque Pessac, Cedex, France Service des Maladies Infectieuses et du Voyageur Tourcoing, France Italy Azienda Ospedaliera Papa Giovanni XXIII Bergamo, Italy Busto Arsizio Hospital Busto Arsizio, Italy IRCCS A.O.U. San Martino Genova, Italy Azienda Ospedaliera Luigi Sacco Milano, Italy Azienda Ospedaliero Universitaria Policlinico di Modena Modena, Italy U.O. Malattie Infettive Pescara, Italy Istituto Nazionale Malattie Infettive Lazzaro Spallanzani I.R.C.C.S. Roma, Italy Azienda Ospedaliero Universitaria di Sassari Sassari, Italy Dipartimento di Malattie Infettive e Tropicali Torino, Italy Spain Hospital Clinic de Barcelona Barcelona, Spain Hospital de la Santa Creu i Sant Pau Barcelona, Spain Hospital Universitari Germans Trias i Pujol Barcelona, Spain Hospital Vall d'Hebron Barcelona, Spain Hospital 12 de Octubre Madrid, Spain Hospital General Universitario Gregorio Maranon Madrid, Spain Hospital Universitario La Paz Madrid, Spain Ramon Y Cajal University Hospital Madrid, Spain Hospital Costa Del Sol Marbella, Spain Hospital General Universitario de Valencia Valencia, Spain United Kingdom Royal Victoria Hospital Belfast, United Kingdom Mortimer Market Centre London, United Kingdom Newcastle Royal Victoria Infirmary Newcastle Upon Tyne, United Kingdom 收起 <<
NCT00197145	Infection, Human Immunodeficie... 展开 >>ncy Virus I 收起 <<	Phase 3	Terminated	-	-
NCT01252940	-		Completed	-	-
NCT02302547	HIV	Phase 3	Completed	-	France ... 展开 >> Unité des Maladies Infectieuses, CHU de CAEN Caen, France, 14033 Service des Maladies Infectieuses, CHR Orléans La Source, ORLEANS CEDEX 2 CHR d'ORLEANS, France, 45067 Service d'Immunologie Clinique centre de Vaccination anti- VIH ANRS Hopital Henri- Mondor Creteil, France, 94010 Service de Médecine Interne et Maladies Infectieuses, Groupe Hospitalier La Rochelle, Cedex 01 La Rochelle, France, 17019 Service de Pneumologie, centre Hospitalier Fontenoy, CH de CHARTRES Le Coudray, France, 28630 CHU de NANCY Nancy, France, 54035 Service des maladies Infectieuses et tropicales, CH GEORGES RENON Niort, France, 79021 Service des Maladies Infectieuses et tropicales, APHP SAINT LOUIS Paris, France, 75475 Hospital Tenon Paris, France, 75970 Centre de diagnostic et thérapeutique, Hopital Hotel Dieu Paris, France, 94010 Consultation Maladies Infectieuses, Chu de Poitiers, Cedex Poitiers, France, 86021 Maladies Infectieuses, CHU de ROUEN Rouen, France, 76031 Service de Médecine Interne, CH de SAINTONGE- BP 326 Saintes, France, 17108 Médecine Interne, Hôpital FOCH Suresnes, France, 92151 Service Universitaire des Maladies Infectieuses et du Voyageur, CH DRON Tourcoing, France, 59200 Service de Medecine Interne et Maladies Infectieuses, CHRU BRETONNEAU, TOURS CEDEX9 Tours, France, 37044 收起 <<
NCT01475838	-		Completed	-	-
NCT00850395	-		Completed	-	-
NCT02016924	Acquired Immune Deficiency Syn... 展开 >>drome (AIDS) HIV Infections 收起 <<	Phase 2 Phase 3	Recruiting	December 2024	United States, California ... 展开 >> Pediatric Infectious Diseases Associate Recruiting Long Beach, California, United States, 90806 Principal Investigator: Jagmohan Batra, MD Children's Hospital Los Angeles Withdrawn Los Angeles, California, United States, 90027 United States, Colorado Children's Hospital Colorado Recruiting Aurora, Colorado, United States, 80045 Principal Investigator: Elizabeth McFarland, MD United States, District of Columbia Children's National Medical Center Recruiting Washington, District of Columbia, United States, 20852 Principal Investigator: Natella Rakhmanina United States, Florida University of South Florida Clinic at Children's Medical Services Recruiting Tampa, Florida, United States, 33620 Principal Investigator: Carina Rodriguez, MD United States, Georgia Emory-Children's Center- Ponce Family and Youth Clinic Completed Atlanta, Georgia, United States, 30308 United States, Massachusetts Boston Medical Center Withdrawn Boston, Massachusetts, United States, 02118 United States, New York Bellevue Hospital Recruiting New York, New York, United States, 10016 Principal Investigator: William Borkowsky, MD SUNY Upstate Medical University Recruiting Syracuse, New York, United States, 13210 Principal Investigator: Leonard Weiner, MD United States, Tennessee St. Jude Children's Research Hospital Recruiting Memphis, Tennessee, United States, 38105 Principal Investigator: Aditya Gaur, MD United States, Texas University of Texas Health Science Center of Houston Recruiting Houston, Texas, United States, 77030 Principal Investigator: Gloria Heresi, MD Argentina Hospital General de Agudos Dr. Cosme Argerich Recruiting Buenos Aires, Argentina, 1151 Principal Investigator: Diego Cecchini Helios Salud S.A. Recruiting Buenos Aires, Argentina, C1131ACG Principal Investigator: Maria R Bologna Hospital Ramos Mejía Recruiting Buenos Aires, Argentina, C1221ADC DF Principal Investigator: Irene Foradori Fundacion Huesped Recruiting Buenos Aires, Argentina Principal Investigator: Pedro Cahn Thailand Siriraj Hospital Mahidol University Recruiting Bangkok, Krung Thep Maha Nakhon, Thailand Principal Investigator: Kulkanya Chokephaibulkit The HIV NAT Research Collaboration Recruiting Bangkok, Krung Thep Maha Nakhon, Thailand Principal Investigator: Sivaporn Getechompol Srinagarind Hospital Khon Kaen University Recruiting Khon Kaen, Thailand Principal Investigator: Pope Kosalaraksa 收起 <<
NCT02605954	HIV-1 Infection	Phase 3	Completed	-	-
NCT02605954	-		Completed	-	-
NCT00445146	HIV Infections	Phase 2	Completed	-	-
NCT01475838	Acquired Immunodeficiency Synd... 展开 >>rome HIV Infections 收起 <<	Phase 3	Completed	-	-
NCT03631732	HIV-1 Infection	Phase 3	Recruiting	August 2020	-
NCT00000912	HIV Infections	Phase 2	Completed	-	-
NCT00445146	-		Completed	-	-
NCT00039741	HIV Infections	Phase 2 Phase 3	Completed	-	-
NCT00192660	HIV-Associated Lipodystrophy S... 展开 >>yndrome Cardiovascular Disease 收起 <<	Phase 4	Completed	-	Australia, New South Wales ... 展开 >> St. Vincent's Hospital Sydney, New South Wales, Australia, 2010 收起 <<
NCT00000918	HIV Infections	Phase 2	Completed	-	-
NCT00102206	HIV Infections	Phase 2	Completed	-	United States, Illinois ... 展开 >> Chicago Children's CRS Chicago, Illinois, United States, 60614 United States, New York Columbia IMPAACT CRS New York, New York, United States SUNY Stony Brook NICHD CRS Stony Brook, New York, United States, 11794-8111 United States, North Carolina DUMC Ped. CRS Durham, North Carolina, United States, 27710 收起 <<
NCT00000891	HIV Infections	Phase 2	Completed	-	United States, Colorado ... 展开 >> Univ of Colorado Health Sciences Ctr Denver, Colorado, United States, 80262 United States, Illinois Rush Presbyterian - Saint Luke's Med Ctr Chicago, Illinois, United States, 60612 United States, Ohio Case Western Reserve Univ Cleveland, Ohio, United States, 44106 收起 <<
NCT01814722	-		Terminated(The trial was termi... 展开 >>nated early due to slow recruitment.) 收起 <<	-	-
NCT00002440	HIV Infections	Phase 2	Completed	-	United States, California ... 展开 >> UCSD Treatment Ctr San Diego, California, United States, 921036329 United States, Connecticut Yale U / New Haven Med Ctr / AIDS Clinical Trials Unit New Haven, Connecticut, United States, 065102483 United States, Missouri Kansas City AIDS Research Consortium Kansas City, Missouri, United States, 64111 United States, New York NYU Med Ctr / Dept of Medicine / AIDS Clinical Trial New York, New York, United States, 10016 United States, North Carolina Carolinas Med Ctr Charlotte, North Carolina, United States, 28232 United States, Ohio Case Western Reserve Univ / AIDS Clinical Trials Unit Cleveland, Ohio, United States, 44106 United States, Pennsylvania Univ of Pittsburgh Med Ctr Pittsburgh, Pennsylvania, United States, 15213 United States, Tennessee Vanderbilt Univ Med Ctr Nashville, Tennessee, United States, 372321302 收起 <<
NCT00039741	-		Completed	-	-
NCT00665847	-		Completed	-	-
NCT01232361	-		Completed	-	United States, Alabama ... 展开 >> Univ. of Alabama Birmingham NICHD CRS (5096) Birmingham, Alabama, United States, 35294 United States, California Miller Children's Hospital Long Beach (5093) Long Beach, California, United States, 90806 Usc La Nichd Crs (5048) Los Angeles, California, United States, 90033 UCLA-Los Angeles/Brazil AIDS Consortium (LABAC) CR (3601) Los Angeles, California, United States, 90095 Univ of California, San Diego (UCSD) (4601) San Diego, California, United States, 92103 United States, Colorado Childrens Hospital (U. Colorado, Denver) NICHD CRS (5052) Denver, Colorado, United States, 80218-1088 United States, District of Columbia Children's National Med. Ctr. Washington DC NICHD CRS (5015) Washington, District of Columbia, United States, 20010 United States, Florida South Florida CDC Ft Lauderdale NICHD CRS (5055) Ft Lauderdal, Florida, United States, 33316 Univ of Miami Pediatric/Perinatal HIV/AIDS (4201) Miami, Florida, United States, 33136 United States, Illinois Chicago Children's CRS (4001) Chicago, Illinois, United States, 60611 Rush University Cook County Hospital NICHD CRS (5083) Chicago, Illinois, United States, 60612 United States, Maryland Johns Hopkins University NICHD CRS (5092) Baltimore, Maryland, United States, 21287 United States, Massachusetts Boston Medical Center Ped. HIV Program NICHD CRS (5011) Boston, Massachusetts, United States, 02118 WNE Maternal Pediatric Adolescent AIDS CRS (7301) Worcester, Massachusetts, United States, 01605 United States, Michigan Wayne State University/Children's Hospital of Michigan NICHD CRS (5041) Detroit, Michigan, United States, 48201 United States, New York Jacobi Med. Ctr. Bronx NICHD CRS (5013) Bronx, New York, United States, 10461 New York University NY (5012) New York, New York, United States, 10016 Columbia IMPAACT Center (4101) New York, New York, United States, 10032 SUNY Stony Brook (5040) Stony Brook, New York, United States, 11794-8111 United States, Tennessee St. Jude Childrens Research Hospital, Memphis (6501) Memphis, Tennessee, United States, 38105-2794 United States, Texas Texas Children's Hosp. CRS (3801) Houston, Texas, United States, 77030 Puerto Rico San Juan City Hosp. PR NICHD CRS (5031) San Juan, Puerto Rico, 00927 收起 <<
NCT00046033	HIV Infections	Phase 2	Completed	-	United States, Florida ... 展开 >> Univ of Miami Miami, Florida, United States, 33136-1013 United States, Hawaii Univ of Hawaii Honolulu, Hawaii, United States, 96816-2396 United States, New York NYU/Bellevue New York, New York, United States, 10016 United States, Ohio Case Western Reserve Univ Cleveland, Ohio, United States, 44106 United States, Pennsylvania Univ of Pittsburgh Pittsburgh, Pennsylvania, United States, 15213-2582 United States, Texas Univ of Texas, Galveston Galveston, Texas, United States, 77555-0435 收起 <<
NCT00032669	HIV Infections	Phase 1	Completed	-	United States, Maryland ... 展开 >> National Cancer Institute (NCI) Bethesda, Maryland, United States, 20892 收起 <<
NCT01814722	-		Terminated(The trial was termi... 展开 >>nated early due to slow recruitment.) 收起 <<	-	-
NCT00006519	HIV Infection	Phase 1	Completed	-	United States, Maryland ... 展开 >> National Cancer Institute (NCI) Bethesda, Maryland, United States, 20892 收起 <<
NCT02180438	HIV-2 Infection	Phase 4	Completed	-	Senegal ... 展开 >> Clinique des Maladies Infectieuses Ibrahima DIOP Mar/CRCF, Centre Hospitalier Universitaire de Fann Dakar, Senegal 收起 <<
NCT00003008	Sarcoma	Phase 2	Completed	-	United States, Alabama ... 展开 >> University of Alabama at Birmingham Comprehensive Cancer Center Birmingham, Alabama, United States, 35294-3300 收起 <<
NCT00307502	HIV Infections	Phase 1	Completed	-	Spain ... 展开 >> Germans Trias i Pujol Hospital Badalona, Barcelona, Spain, 08916 Hospital de Figueres Figueras, Barcelona, Spain, 17600 Fundació Hospital-Asil de Granollers Granollers, Barcelona, Spain, 08400 Hospital de Vic Vic, Barcelona, Spain, 08500 Hospital Universitari Sant Joan de Reus Reus, Tarragona, Spain, 43201 Hospital de la Santa Creu i Sant Pau Barcelona, Spain, 08025 收起 <<
NCT00411957	HIV Infections	Phase 1 Phase 2	Completed	-	Thailand ... 展开 >> HIV-NAT, Thai Red Cross AIDS Research Center Bangkok, Thailand, 10300 收起 <<
NCT00002213	HIV Infections	Phase 2	Completed	-	United States, California ... 展开 >> East Bay AIDS Ctr Berkeley, California, United States, 94705 Kraus Med Partners Los Angeles, California, United States, 90036 United States, Illinois Northwestern Univ Med School AIDS Treatment Unit Chicago, Illinois, United States, 60611 United States, Maryland Niaid / Nih Bethesda, Maryland, United States, 20892 United States, Massachusetts Beth Israel Deaconess Med Ctr Boston, Massachusetts, United States, 02215 United States, New York Saint Vincents Hosp / AIDS Ctr / 4th Floor New York, New York, United States, 10011 United States, North Carolina Univ of North Carolina Chapel Hill Chapel Hill, North Carolina, United States, 27499 United States, Ohio Univ Int Med Assoc Inc / Holmes Hosp / U of Cincinnati Cincinnati, Ohio, United States, 45267 United States, Rhode Island The Miriam Hosp Providence, Rhode Island, United States, 02906 收起 <<
NCT00476606	-		Recruiting	December 2020	Thailand ... 展开 >> HIV-NAT Recruiting Bangkok, Thailand, 10330 Contact: June Ohata, BS, BA 662-652-3040 juneohata4@gmail.com Sub-Investigator: Thanyawee Puthanakit, MD Pediatric infectious diseases section, Chulalongkorn University Recruiting Bangkok, Thailand, 10330 Contact: Chitsanu Pancharoen, MD Khon Kaen University Recruiting Khon Kaen, Thailand, 40002 Contact: Pope Kosalaraksa, MD Sub-Investigator: Chulapan Engchanil, MD Sub-Investigator: Pagakrong Lumbiganon, MD 收起 <<
NCT00001108	HIV Infections	Phase 1	Completed	-	United States, Alabama ... 展开 >> Univ of Alabama at Birmingham - Pediatric Birmingham, Alabama, United States, 35233 United States, California UCLA Med Ctr / Pediatric Los Angeles, California, United States, 900951752 United States, Florida Univ of Miami (Pediatric) Miami, Florida, United States, 33161 Sacred Heart Children's Hosp / CMS of Florida Pensacola, Florida, United States, 32503 United States, Illinois Cook County Hosp Chicago, Illinois, United States, 60612 Chicago Children's Memorial Hosp Chicago, Illinois, United States, 606143394 United States, Louisiana Tulane Univ / Charity Hosp of New Orleans New Orleans, Louisiana, United States, 701122699 United States, Maryland Johns Hopkins Hosp - Pediatric Baltimore, Maryland, United States, 212874933 United States, Massachusetts Children's Hosp of Boston Boston, Massachusetts, United States, 021155724 Univ of Massachusetts Med School Worcester, Massachusetts, United States, 016550001 United States, Mississippi Univ of Mississippi Med Ctr Jackson, Mississippi, United States, 39213 United States, New Jersey Univ of Medicine & Dentistry of New Jersey / Univ Hosp Newark, New Jersey, United States, 071032714 United States, New York North Shore Univ Hosp Great Neck, New York, United States, 11021 Bellevue Hosp / New York Univ Med Ctr New York, New York, United States, 10016 Columbia Presbyterian Med Ctr New York, New York, United States, 10032 Incarnation Children's Ctr / Columbia Presbyterian Med Ctr New York, New York, United States, 10032 SUNY Health Sciences Ctr at Syracuse / Pediatrics Syracuse, New York, United States, 13210 United States, Tennessee Saint Jude Children's Research Hosp of Memphis Memphis, Tennessee, United States, 381052794 United States, Virginia Med College of Virginia Richmond, Virginia, United States, 23219 收起 <<
NCT00665847	HIV-1	Phase 2	Completed	-	-
NCT00004584	HIV Infections	Phase 2	Completed	-	-
NCT00717067	-		Completed	-	-
NCT00051831	HIV Infections	Not Applicable	Completed	-	United States, Colorado ... 展开 >> University of Colorado Hospital CRS Aurora, Colorado, United States, 80262-3706 United States, Massachusetts Massachusetts General Hospital ACTG CRS Boston, Massachusetts, United States, 02114 United States, Missouri Washington U CRS St. Louis, Missouri, United States, 63108-2138 United States, New York NY Univ. HIV/AIDS CRS New York, New York, United States, 10016-6481 United States, North Carolina Unc Aids Crs Chapel Hill, North Carolina, United States, 27514 United States, Ohio The Ohio State Univ. AIDS CRS Columbus, Ohio, United States Puerto Rico Puerto Rico-AIDS CRS San Juan, Puerto Rico, 00936-5067 收起 <<
NCT00001087	HIV Infections	Phase 2	Completed	-	United States, Illinois ... 展开 >> Northwestern University CRS Chicago, Illinois, United States, 60611 Cook County Hosp. CORE Ctr. Chicago, Illinois, United States, 60612 Rush Univ. Med. Ctr. ACTG CRS Chicago, Illinois, United States, 60612 United States, Maryland Johns Hopkins Adult AIDS CRS Baltimore, Maryland, United States, 21287 United States, New York NY Univ. HIV/AIDS CRS New York, New York, United States Puerto Rico Puerto Rico-AIDS CRS San Juan, Puerto Rico, 009365067 收起 <<
NCT00002184	HIV Infections	Phase 2	Completed	-	United States, Arizona ... 展开 >> Phoenix Body Positive Phoenix, Arizona, United States, 85016 United States, California Krauss Med Partners / Dept of Research and Development Los Angeles, California, United States, 90036 UCLA Care Ctr Los Angeles, California, United States, 900951793 Davies Med Ctr San Francisco, California, United States, 94114 United States, Connecticut Blick Med Associates Greenwich, Connecticut, United States, 06830 United States, District of Columbia George Washington Med Ctr Washington, District of Columbia, United States, 20037 United States, Maryland Johns Hopkins Univ School of Medicine Baltimore, Maryland, United States, 21287 United States, Massachusetts Univ of Massachusetts Med Ctr Worcester, Massachusetts, United States, 01655 United States, New York North Shore Community Hosp Manhassett, New York, United States, 11030 United States, Oklahoma Associates of Med and Mental Health Tulsa, Oklahoma, United States, 74114 United States, Pennsylvania Univ of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 United States, Rhode Island Mem Hosp of Rhode Island Pawtucket, Rhode Island, United States, 02860 United States, Texas Univ of Texas Southwestern Med Ctr of Dallas Dallas, Texas, United States, 75235 Puerto Rico Hosp Regional de Ponce - Area Vieja Ponce, Puerto Rico, 00731 San Juan AIDS Program Santruce, Puerto Rico, 00908 收起 <<
NCT02180438	-		Completed	-	-
NCT00000941	HIV Infections	Phase 1	Completed	-	United States, California ... 展开 >> Univ of Southern California / LA County USC Med Ctr Los Angeles, California, United States, 900331079 San Francisco Gen Hosp San Francisco, California, United States, 941102859 Stanford Univ Med Ctr Stanford, California, United States, 943055107 United States, Colorado Univ of Colorado Health Sciences Ctr Denver, Colorado, United States, 80262 United States, Florida Univ of Miami School of Medicine Miami, Florida, United States, 331361013 United States, Hawaii Univ of Hawaii Honolulu, Hawaii, United States, 96816 United States, Indiana Indiana Univ Hosp Indianapolis, Indiana, United States, 462025250 United States, Louisiana Tulane Univ School of Medicine New Orleans, Louisiana, United States, 70112 United States, Maryland Johns Hopkins Hosp Baltimore, Maryland, United States, 21287 United States, Minnesota Univ of Minnesota Minneapolis, Minnesota, United States, 55455 United States, New York Bellevue Hosp / New York Univ Med Ctr New York, New York, United States, 10016 United States, South Carolina Julio Arroyo West Columbia, South Carolina, United States, 29169 United States, Washington Univ of Washington Seattle, Washington, United States, 98104 收起 <<
NCT00000874	-		Completed	-	United States, California ... 展开 >> Community Consortium / UCSF San Francisco, California, United States, 94110 Community Consortium of San Francisco San Francisco, California, United States, 94110 United States, Colorado Alpine Family Medicine / Janowski Denver, Colorado, United States, 80204 Denver CPCRA / Denver Public Hlth Denver, Colorado, United States, 80204 S Denver Infectious Diseases Specialists Denver, Colorado, United States, 80204 VA Med Ctr Denver, Colorado, United States, 80204 United States, District of Columbia Montgomery County Health Dept Washington, District of Columbia, United States, 20422 Veterans Administration Med Ctr / Regional AIDS Program Washington, District of Columbia, United States, 20422 United States, Georgia AIDS Research Consortium of Atlanta Atlanta, Georgia, United States, 30308 United States, Illinois AIDS Research Alliance - Chicago Chicago, Illinois, United States, 60657 United States, Louisiana Louisiana Comm AIDS Rsch Prog / Tulane Univ Med New Orleans, Louisiana, United States, 70112 United States, Michigan Wayne State Univ / WSU / DMC HIV / AIDS Program Detroit, Michigan, United States, 48201 Henry Ford Hosp Detroit, Michigan, United States, 48202 United States, New Jersey Mercer Area Early Intervention Services Camden, New Jersey, United States, 08103 Southern New Jersey AIDS Cln Trials / Dept of Med Camden, New Jersey, United States, 08103 North Jersey Community Research Initiative Newark, New Jersey, United States, 07103 United States, New Mexico Partners in Research / New Mexico Albuquerque, New Mexico, United States, 87131 Partners Research Albuquerque, New Mexico, United States, 87131 T A Ferrill Regional HIV Clinic Albuquerque, New Mexico, United States, 87131 United States, New York Harlem AIDS Treatment Group / Harlem Hosp Ctr New York, New York, United States, 10037 United States, Oregon The Research and Education Group Portland, Oregon, United States, 97210 United States, Pennsylvania Philadelphia FIGHT Philadelphia, Pennsylvania, United States, 19107 Saint Joseph's Hosp Philadelphia, Pennsylvania, United States, 19107 United States, Virginia Richmond AIDS Consortium Richmond, Virginia, United States, 23298 收起 <<
NCT00624195	HIV Infections	Phase 2 Phase 3	Completed	-	United States, California ... 展开 >> HIV Neurobehavioral Research Center, University of California San Diego San Diego, California, United States, 92103 University of California, San Francisco San Francisco, California, United States, 94110 United States, Maryland Johns Hopkins University- School of Medicine Baltimore, Maryland, United States, 21287 United States, Missouri Washington University St. Louis, Missouri, United States, 63110 United States, New York Mount Sinai Medical Center New York, New York, United States, 10024 收起 <<
NCT00624195	-		Completed	-	-
NCT00717067	Human Immunodeficiency Virus (... 展开 >>HIV) Infection 收起 <<	Phase 4	Completed	-	Germany ... 展开 >> Pfizer Investigational Site Berlin, Germany, 10117 Pfizer Investigational Site Muenchen, Germany, 81241 收起 <<
NCT00285883	Directly Observed Therapy ... 展开 >> HIV Infections 收起 <<	Phase 3	Completed	-	United States, New Jersey ... 展开 >> Saint Michael's Medical Center Newark, New Jersey, United States, 07102 收起 <<
NCT00002372	HIV Infections	Phase 1	Completed	-	United States, California ... 展开 >> Univ of California / San Diego Treatment Ctr San Diego, California, United States, 92103 ViRx Inc San Francisco, California, United States, 94109 United States, North Carolina Univ of North Carolina at Chapel Hill / Duke Univ Med Ctr Durham, North Carolina, United States, 27710 收起 <<
NCT00100984	HIV Infection	Phase 4	Terminated(Insufficient enroll... 展开 >>ment) 收起 <<	-	United States, Alabama ... 展开 >> Hobson City, Alabama, United States, 36201 United States, California Los Angeles, California, United States, 90033 Los Angeles, California, United States, 90036 United States, District of Columbia Washington, D.C., District of Columbia, United States, 20007 Washington, D.C., District of Columbia, United States, 20009 United States, Florida Orlando, Florida, United States, 32803 United States, Georgia Atlanta, Georgia, United States, 30308 Macon, Georgia, United States, 31201 United States, Illinois Chicago, Illinois, United States, 60612 Chicago, Illinois, United States, 60657 United States, Maryland Baltimore, Maryland, United States, 21201 United States, Massachusetts Boston, Massachusetts, United States, 02215-3318 United States, Mississippi Jackson, Mississippi, United States, 39216-4505 United States, Missouri Saint Louis, Missouri, United States, 63139 United States, New Jersey Newark, New Jersey, United States, 07103 United States, New York New York, New York, United States, 10011 New York, New York, United States, 10016 United States, North Carolina Huntersville, North Carolina, United States, 28078 United States, Texas Dallas, Texas, United States, 75246 Houston, Texas, United States, 77004 收起 <<
NCT00005762	HIV Infections	Not Applicable	Completed	-	United States, California ... 展开 >> Stanford CRS Palo Alto, California, United States, 943055107 United States, Colorado University of Colorado Hospital CRS Aurora, Colorado, United States, 80262 United States, Hawaii Univ. of Hawaii at Manoa, Leahi Hosp. Honolulu, Hawaii, United States, 96816 United States, Indiana Indiana Univ. School of Medicine, Infectious Disease Research Clinic Indianapolis, Indiana, United States, 462025250 United States, Maryland Johns Hopkins Adult AIDS CRS Baltimore, Maryland, United States United States, Ohio The Ohio State University Medical Center Columbus, Ohio, United States, 43210 United States, Tennessee Vanderbilt Univ. Med. Ctr., AIDS Clinical Trials Ctr. Nashville, Tennessee, United States, 37203 United States, Washington University of Washington AIDS CRS Seattle, Washington, United States, 98104 收起 <<
NCT00000892	HIV Infections	Not Applicable	Completed	-	-
NCT00002447	HIV Infections	Phase 3	Completed	-	-
NCT00476502	-		Completed	-	Thailand ... 展开 >> The HIV Netherlands Australia Thailand Research Collaboration (HIV-NAT) Bangkok, Thailand, 10330 收起 <<
NCT00056641	HIV Infections	Phase 2	Completed	-	-
NCT00122603	HIV Infections	Phase 2	Completed	-	France ... 展开 >> Service des Maladies infectieuses et tropicales Hopital Bichat Claude Bernard Paris, France, 75018 收起 <<
NCT00001133	HIV Infections	Phase 1	Completed	-	United States, Alabama ... 展开 >> Alabama Therapeutics CRS Birmingham, Alabama, United States, 35294 United States, California USC CRS Los Angeles, California, United States, 900331079 Ucsf Aids Crs San Francisco, California, United States, 94110 United States, Maryland Johns Hopkins Adult AIDS CRS Baltimore, Maryland, United States, 21287 United States, New York NY Univ. HIV/AIDS CRS New York, New York, United States, 10016 United States, Ohio Univ. of Cincinnati CRS Cincinnati, Ohio, United States, 452670405 United States, Pennsylvania Pitt CRS Pittsburgh, Pennsylvania, United States, 15213 收起 <<
NCT00002334	HIV Infections	Phase 3	Completed	-	-
NCT00002347	HIV Infections	Phase 2	Completed	-	United States, Massachusetts ... 展开 >> PAREXEL Intl Corp / InterCo Collaboration Ctr Waltham, Massachusetts, United States, 02154 收起 <<
NCT02023450	Pulmonary Arterial Hypertensio... 展开 >>n 收起 <<	Early Phase 1	Unknown	July 2015	China, Hunan ... 展开 >> Xiangya hospital Recruiting Changsha, Hunan, China Contact: YU ZAI XIN, PhD 0086-13875873205 yuzaixin@126.com 收起 <<
NCT00001040	HIV Infections	Phase 2	Completed	-	United States, Alabama ... 展开 >> Univ of Alabama at Birmingham Birmingham, Alabama, United States, 35294 United States, California Stanford Univ Med Ctr Stanford, California, United States, 943055107 United States, Colorado Univ of Colorado Health Sciences Ctr Denver, Colorado, United States, 80262 United States, Illinois Northwestern Univ Med School Chicago, Illinois, United States, 60611 United States, New York Bellevue Hosp / New York Univ Med Ctr New York, New York, United States, 10016 Univ of Rochester Med Ctr Rochester, New York, United States, 14642 United States, Ohio Ohio State Univ Hosp Columbus, Ohio, United States, 432101228 United States, Pennsylvania Girard Med Ctr Philadelphia, Pennsylvania, United States, 191046073 United States, Texas Univ TX Galveston Med Branch Galveston, Texas, United States, 775550882 United States, Washington Univ of Washington Seattle, Washington, United States, 98122 收起 <<
NCT00002378	HIV Infections	Phase 3	Completed	-	-
NCT00000906	HIV Infections	Phase 1	Completed	-	United States, California ... 展开 >> San Francisco Gen Hosp San Francisco, California, United States, 941102859 United States, Colorado Univ of Colorado Health Sciences Ctr Denver, Colorado, United States, 80262 United States, Maryland Johns Hopkins Hosp Baltimore, Maryland, United States, 21287 United States, New York Beth Israel Med Ctr New York, New York, United States, 10003 Chelsea Ctr New York, New York, United States, 10021 Cornell Univ Med Ctr New York, New York, United States, 10021 Mount Sinai Med Ctr New York, New York, United States, 10029 收起 <<
NCT00002162	HIV Infections	Phase 2	Completed	-	-
NCT01297127	-		Completed	-	Poland ... 展开 >> Bialystok, Poland, 15-540 Bydgoszcz, Poland, 85-030 Chorzow, Poland, 41-500 Krakow, Poland, 31-531 Lodz, Poland, 91-347 Warszawa, Poland, 01-201 Wroclaw, Poland, 53-208 Zielona góra, Poland, 65-045 收起 <<
NCT00001094	HIV Infections	Phase 2	Withdrawn	-	United States, California ... 展开 >> Willow Clinic Menlo Park, California, United States, 94025 Stanford Univ Med Ctr Stanford, California, United States, 943055107 United States, Colorado Univ of Colorado Health Sciences Ctr Denver, Colorado, United States, 80262 United States, Florida Univ of Miami School of Medicine Miami, Florida, United States, 331361013 United States, Georgia Emory Univ Atlanta, Georgia, United States, 30308 United States, Hawaii Queens Med Ctr Honolulu, Hawaii, United States, 96816 Univ of Hawaii Honolulu, Hawaii, United States, 96816 United States, Illinois Louis A Weiss Memorial Hosp Chicago, Illinois, United States, 60640 United States, Louisiana Tulane Univ School of Medicine New Orleans, Louisiana, United States, 70112 United States, New York SUNY / Erie County Med Ctr at Buffalo Buffalo, New York, United States, 14215 Bellevue Hosp / New York Univ Med Ctr New York, New York, United States, 10016 United States, North Carolina Carolinas Med Ctr Charlotte, North Carolina, United States, 28203 Moses H Cone Memorial Hosp Greensboro, North Carolina, United States, 27401 United States, Ohio Univ of Cincinnati Cincinnati, Ohio, United States, 452670405 Ohio State Univ Hosp Clinic Columbus, Ohio, United States, 432101228 United States, Texas Univ of Texas Galveston Galveston, Texas, United States, 775550435 Puerto Rico Univ of Puerto Rico San Juan, Puerto Rico, 009365067 收起 <<
NCT00000920	HIV Infections ... 展开 >> Pregnancy 收起 <<	Phase 1	Completed	-	United States, California ... 展开 >> Los Angeles County - USC Med Ctr Los Angeles, California, United States, 90033 United States, Colorado Univ of Colorado Health Sciences Ctr Denver, Colorado, United States, 80262 United States, District of Columbia Howard Univ Hosp Washington, District of Columbia, United States, 20060 United States, Florida Univ of Miami / Jackson Memorial Hosp Miami, Florida, United States, 33136 Univ of Miami (Pediatric) Miami, Florida, United States, 33161 United States, Illinois Univ of Illinois College of Medicine / Pediatrics Chicago, Illinois, United States, 60612 United States, Louisiana Tulane Univ / Charity Hosp of New Orleans New Orleans, Louisiana, United States, 701122699 Univ Hosp New Orleans, Louisiana, United States, 70112 United States, Michigan Children's Hosp of Michigan Detroit, Michigan, United States, 48201 United States, New Jersey Univ of Medicine & Dentistry of New Jersey / Univ Hosp Newark, New Jersey, United States, 071032714 United States, New York Columbia Presbyterian Med Ctr New York, New York, United States, 10032 United States, North Carolina Duke Univ Med Ctr Durham, North Carolina, United States, 277103499 United States, South Carolina Med Univ of South Carolina Charleston, South Carolina, United States, 294253312 United States, Washington Children's Hospital & Medical Center / Seattle ACTU Seattle, Washington, United States, 981050371 Puerto Rico Univ of Puerto Rico / Univ Children's Hosp AIDS San Juan, Puerto Rico, 009365067 收起 <<
NCT00035932	HIV Infections	Phase 3	Completed	-	-
NCT00043953	HIV Infections	Phase 2	Completed	-	United States, California ... 展开 >> AHF Research Los Angeles, California, United States, 90015 Stephen Becker, MD San Francisco,, California, United States, 94115 Pacific Horizon Medical Group San Francisco, California, United States, 94115 Harbor UCLA, Research & Education Institute Torrance, California, United States, 90502 United States, Massachusetts Community Research Initiative of New England Boston,, Massachusetts, United States, 02215 Community Research Initiative of New England Springfield, Massachusetts, United States, 01107 United States, North Carolina University of North Carolina at Chapel Hill Chapel Hill,, North Carolina, United States, 27599 The University of North Carolina at Chapel Hill Chapel Hill, North Carolina, United States, 27599-7215 Duke University Medical Center Durham, North Carolina, United States, 27710 Canada University of Ottawa at the Ottawa Health Research Institute Ottawa,, Canada, K1H 8L6 University of Ottawa Health Research Institute Ottawa, Canada, K1H 8L6 收起 <<
NCT00035932	-		Completed	-	-
NCT00038532	HIV Infections	Phase 2	Completed	-	-
NCT00002178	HIV Infections	Phase 3	Completed	-	United States, California ... 展开 >> Dr Charles Farthing Los Angeles, California, United States, 90048 United States, Massachusetts Community Research Initiative Brookline, Massachusetts, United States, 02445 收起 <<
NCT02239835	HIV Infections	Phase 2	Terminated	-	-
NCT00002448	HIV Infections	Phase 3	Completed	-	United States, California ... 展开 >> UCLA Care Ctr Los Angeles, California, United States, 900951793 Palo Alto Veterans Affairs Health Care System Palo Alto, California, United States, 94304 United States, New Jersey Robert Wood Johnson Med School/UMDNJ New Brunswick, New Jersey, United States, 089030019 收起 <<
NCT00002397	HIV Infections ... 展开 >> AIDS-Associated Nephropathy 收起 <<	Phase 3	Completed	-	United States, New York ... 展开 >> Mount Sinai Med Ctr New York, New York, United States, 10029 收起 <<
NCT00050180	Healthy HIV I... 展开 >>nfections 收起 <<	Phase 4	Completed	-	United States, Maryland ... 展开 >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 收起 <<
NCT00002374	HIV Infections	Phase 3	Completed	-	United States, California ... 展开 >> Pacific Oaks Med Ctr Beverly Hills, California, United States, 90211 Tower Infectious Diseases / Med Associates Inc Los Angeles, California, United States, 90048 United States, Florida Community Research Initiative of South Florida Coral Gables, Florida, United States, 33146 Ctr for Quality Care Tampa, Florida, United States, 33609 United States, Massachusetts Community Research Initiative of New England Brookline, Massachusetts, United States, 02445 United States, New York AIDS Ctr New York, New York, United States, 10011 United States, Pennsylvania Anderson Clinical Research / Inc Pittsburgh, Pennsylvania, United States, 15213 收起 <<
NCT00400738	HIV Infections	Phase 2	Completed	-	Thailand ... 展开 >> The HIV Netherlands Australia Thailand Research Collaboration Bangkok, Thailand, 10330 收起 <<
NCT00002367	HIV Infections	Phase 3	Completed	-	United States, California ... 展开 >> AIDS Healthcare Foundation Labs Los Angeles, California, United States, 90048 United States, Florida Urgent Care Ctr / North Broward Hosp District Fort Lauderdale, Florida, United States, 33316 收起 <<
NCT00000898	HIV Infections	Not Applicable	Completed	-	United States, California ... 展开 >> San Francisco Gen Hosp San Francisco, California, United States, 941102859 Univ of California/ San Francisco / Dept of Medicine San Francisco, California, United States, 94110 Stanford Univ Med Ctr Stanford, California, United States, 943055107 United States, Maryland Johns Hopkins Hosp Baltimore, Maryland, United States, 21287 收起 <<
NCT00038519	HIV Infections	Phase 2 Phase 3	Completed	-	-
NCT00002333	HIV Infections	Phase 2	Completed	-	-
NCT00002380	HIV Infections	Phase 1	Completed	-	United States, New Jersey ... 展开 >> Hoffmann - La Roche Inc Nutley, New Jersey, United States, 071101199 收起 <<
NCT00477048	IDV Associated Nephrotoxicity	Phase 2	Completed	-	Thailand ... 展开 >> The HIV Netherlands Australia Thailand Research Collaboration (HIV-NAT) Bangkok, Thailand, 10330 收起 <<
NCT00002111	HIV Infections	Phase 1	Completed	-	United States, California ... 展开 >> Stanford Univ School of Medicine Stanford, California, United States, 943055107 收起 <<
NCT00084058	HIV Infections	Phase 1 Phase 2	Completed	-	United States, Alabama ... 展开 >> UAB, Dept. of Ped., Div. of Infectious Diseases Birmingham, Alabama, United States, 35233 United States, California Long Beach Memorial Med. Ctr., Miller Children's Hosp. Long Beach, California, United States, 90801 UCSF Pediatric AIDS CRS San Francisco, California, United States, 94143-0105 United States, Illinois Chicago Children's CRS Chicago, Illinois, United States, 60614 United States, Louisiana Tulane/LSU Maternal/Child CRS New Orleans, Louisiana, United States, 70112-2699 United States, Maryland Johns Hopkins Hosp. & Health System - Dept. of Peds., Div. of Infectious Diseases Baltimore, Maryland, United States United States, Massachusetts HMS - Children's Hosp. Boston, Div. of Infectious Diseases Boston, Massachusetts, United States United States, New York Jacobi Med. Ctr. Bronx, New York, United States, 10461 Harlem Hosp. Ctr. NY NICHD CRS New York, New York, United States, 10037 Nyu Ny Nichd Crs New York, New York, United States Strong Memorial Hospital Rochester NY NICHD CRS Rochester, New York, United States, 14642-0001 United States, North Carolina DUMC Ped. CRS Durham, North Carolina, United States, 27705 United States, Tennessee St. Jude/UTHSC CRS Memphis, Tennessee, United States, 38105-2794 Puerto Rico Univ. of Puerto Rico Ped. HIV/AIDS Research Program CRS San Juan, Puerto Rico, 00936-5067 San Juan City Hosp. PR NICHD CRS San Juan, Puerto Rico 收起 <<
NCT00000913	HIV Infections	Phase 2	Completed	-	-
NCT00000848	HIV Infections	Phase 2	Completed	-	United States, California ... 展开 >> Stanford CRS Palo Alto, California, United States, 94304 Ucsf Aids Crs San Francisco, California, United States, 94110 Harbor-UCLA Med. Ctr. CRS Torrance, California, United States, 90502 United States, Colorado University of Colorado Hospital CRS Aurora, Colorado, United States, 80045 United States, Florida Univ. of Miami AIDS CRS Miami, Florida, United States, 33136 United States, Illinois Northwestern University CRS Chicago, Illinois, United States, 60611 Rush Univ. Med. Ctr. ACTG CRS Chicago, Illinois, United States, 60612 United States, Massachusetts Massachusetts General Hospital ACTG CRS Boston, Massachusetts, United States, 02114 United States, Missouri Washington U CRS St. Louis, Missouri, United States, 63110 St. Louis ConnectCare, Infectious Diseases Clinic St. Louis, Missouri, United States, 63112 United States, New York SUNY - Buffalo, Erie County Medical Ctr. Buffalo, New York, United States, 14260 Beth Israel Med. Ctr. (Mt. Sinai) New York, New York, United States, 10003 NY Univ. HIV/AIDS CRS New York, New York, United States, 10016 Univ. of Rochester ACTG CRS Rochester, New York, United States, 14642 United States, Ohio The Ohio State Univ. AIDS CRS Columbus, Ohio, United States, 43210 United States, Washington University of Washington AIDS CRS Seattle, Washington, United States, 98104 收起 <<
NCT00623597	HIV Infections	Phase 2	Completed	-	Argentina ... 展开 >> Buenos Aires, Argentina, 1202 Buenos Aires, Argentina, 1425 Santa Fe, Argentina, 3000 Spain Madrid, Spain, 28046 Madrid, Spain, 28905 Valencia, Spain, 46009 Thailand Bangkok, Thailand, 10400 Khon Kaen, Thailand, 40002 Pathumwan, Thailand, 10330 Payathai, Thailand, 10400 收起 <<
NCT00002190	HIV Infections	Phase 2	Completed	-	United States, California ... 展开 >> Davies Med Ctr / c/o HIV Institute San Francisco, California, United States, 94114 Pacific Oaks Med Group / Rsch & Scientific Investigation Sherman Oaks, California, United States, 91403 United States, New York Columbia Presbyterian Med Ctr New York, New York, United States, 10032 收起 <<
NCT00145561	HIV Infections	Phase 1 Phase 2	Completed	-	Germany ... 展开 >> University of Bonn Bonn, Germany, 53127 University of Cologne Köln, Germany Netherlands Rijnstate Hospital Arnhem, Netherlands, 6815AD University of Leiden Leiden, Netherlands, 2300RC Radboud University Medical Centre Nijmegen Nijmegen, Netherlands, 6500HB Erasmus Medical Centre Rotterdam, Netherlands Spain University Hospital ''Germans Trias i Pujol'' Barcelona, Spain, 08916 Thailand Clinic Rajdumri Road Pathumwan Bangkok, Thailand, 10330 United Kingdom Birmingham Heartlands & Sollihull Hospital Birmingham, United Kingdom Chelsea and Westminster Hospital London, United Kingdom, SW10 9NH 收起 <<
NCT00002229	HIV Infections	Phase 4	Completed	-	-
NCT00623597	-		Completed	-	-
NCT00002383	HIV Infections	Phase 1	Completed	-	United States, Alabama ... 展开 >> Univ of Alabama at Birmingham / 1917 Rsch Cln Birmingham, Alabama, United States, 35294 United States, California Davis Med Ctr San Francisco, California, United States, 94114 Mt Zion Hosp of UCSF / HIV Research Ctr San Francisco, California, United States, 94115 Pacific Oaks Med Group / Research & Scientific Investiga Sherman Oaks, California, United States, 91403 United States, Louisiana Tulane Univ Med Ctr / Infectious Diseases Sect New Orleans, Louisiana, United States, 70112 United States, Massachusetts New England Med Ctr Boston, Massachusetts, United States, 02111 United States, Missouri Kansas City AIDS Research Consortium Kansas City, Missouri, United States, 64108 United States, New York Harkness Pavilion New York, New York, United States, 10032 United States, Oregon Oregon Health Sciences Univ Portland, Oregon, United States, 97201 United States, Texas Univ of Texas Med Branch / Virology Clinic Galveston, Texas, United States, 775550882 收起 <<
NCT00002425	HIV Infections	Phase 4	Completed	-	United States, New Jersey ... 展开 >> Consumer Contact Nutley, New Jersey, United States, 071101199 收起 <<
NCT00622206	HIV Infections	Phase 1 Phase 2	Completed	-	Thailand ... 展开 >> HIV-NAT Bangkok, Thailand, 10330 收起 <<
NCT00476359	HIV Infections	Phase 4	Completed	-	Thailand ... 展开 >> Chulalongkorn University Hospital, Department of Pediatrics Bangkok, Thailand, 10330 The HIV Netherlands Australia Thailand Research Collaboration Bangkok, Thailand, 10330 Khon Kaen University Khon Kaen, Thailand, 40002 收起 <<
NCT00389402	HIV Infections	Phase 4	Completed	-	Netherlands ... 展开 >> Academic Medical Centre, University of Amsterdam Amsterdam, Netherlands, 1105 AZ 收起 <<
NCT00002382	HIV Infections	Phase 3	Completed	-	United States, New Jersey ... 展开 >> Hoffmann - La Roche Inc Nutley, New Jersey, United States, 071101199 收起 <<
NCT00476983	Saquinavir/Ritonavir BID or Lo... 展开 >>pinavir/Ritonavir BID 收起 <<	Phase 2 Phase 3	Withdrawn(No funding)	-	-
NCT01638650	HIV Infections	Phase 1	Completed	-	United Kingdom ... 展开 >> London, United Kingdom, SW10 9NH 收起 <<
NCT00435929	-		Completed	-	-
NCT00192608	HIV Infections	Not Applicable	Completed	-	Australia, New South Wales ... 展开 >> St Vincents Hospital Sydney, New South Wales, Australia, 2010 收起 <<
NCT00105079	-		Completed	-	-
NCT00435929	HIV Infections	Phase 1	Completed	-	United States, Illinois ... 展开 >> Chicago, Illinois, United States, 60612 United States, New Jersey Somers Point, New Jersey, United States, 08244 Voorhees, New Jersey, United States, 08043 United States, Pennsylvania Philadelphia, Pennsylvania, United States, 19104 United States, Texas Dallas, Texas, United States, 75204 Canada, Ontario Ottawa, Ontario, Canada, K1H 8L6 Toronto, Ontario, Canada, M5G 2C4 Puerto Rico San Juan, Puerto Rico, 00927 收起 <<
NCT00379405	HIV Infections	Phase 4	Completed	-	Spain ... 展开 >> Germans Trias i Pujol University Hospital Badalona, Barcelona, Spain, 08916 Hospital del Sant Pau. Barcelona, Spain, 08025 收起 <<
NCT02184286	HIV Infections	Phase 1	Terminated	-	-
NCT00622141	HIV Infections	Phase 1 Phase 2	Withdrawn(The study was never ... 展开 >>started because the sponsor decided not to manufacture the investigational product.) 收起 <<	-	-
NCT00438152	HIV Infections	Phase 4	Completed	-	United Kingdom ... 展开 >> Royal Free Hampstead NHS Trust London, United Kingdom, NW32QG 收起 <<
NCT00105079	HIV Infections	Phase 3	Completed	-	-

靶点	HIV Protease HIV proteinase, IC50:2.7 nM
描述	Saquinavir is an orally active and selective HIV proteinase inhibitor. It was highly active against HIV in human cells that are acutely or chronically infected with the virus in in vitro study. Saquinavir had IC50 and IC90 values ranged from 1-30nM and 5-80nM, respectively. Recent study found that Saquinavir showed inhibition effect on 2019-nCoV.
作用机制	Saquinavir is a peptide-like substrate analogue that inhibits HIV protease, which is required for the cleavage of viral polyprotein precursor into individual functional proteins as found in infectious HIV, by binding to its active site. Inhibition of HIV protease leads to the production of immature non-infectious virus particles.

CAS号	127779-20-8
分子式	C₃₈H₅₀N₆O₅
分子量	670.84
SMILES Code	O=C(N[C@@H](CC(N)=O)C(N[C@@H](CC1=CC=CC=C1)[C@H](O)CN2[C@H](C(NC(C)(C)C)=O)C[C@@](CCCC3)([H])[C@@]3([H])C2)=O)C4=NC5=CC=CC=C5C=C4
MDL No.	MFCD00866925

别名	Ro 31-8959
运输	蓝冰
InChI Key	QWAXKHKRTORLEM-UGJKXSETSA-N
Pubchem ID	441243

Saquinavir/沙奎那韦

Saquinavir/沙奎那韦纯度/质量文件产品仅供科研

全球学术期刊中引用的产品

Saquinavir/沙奎那韦质控信息

Saquinavir/沙奎那韦生物活性

Saquinavir/沙奎那韦临床研究

Saquinavir/沙奎那韦参考文献

Saquinavir/沙奎那韦实验方案

Saquinavir/沙奎那韦技术信息

最近浏览的产品

大规格询价

摩尔计算器

靶点

总药量计算器

工作液计算器

细胞研究

临床研究

确认信息

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

Saquinavir/沙奎那韦

Saquinavir/沙奎那韦 纯度/质量文件 产品仅供科研

全球学术期刊中引用的产品

Saquinavir/沙奎那韦 质控信息

Saquinavir/沙奎那韦 生物活性

Saquinavir/沙奎那韦 临床研究

Saquinavir/沙奎那韦 参考文献

Saquinavir/沙奎那韦 实验方案

Saquinavir/沙奎那韦 技术信息

最近浏览的产品

大规格询价

摩尔计算器

靶点

总药量计算器

工作液计算器

细胞研究

临床研究

确认信息

请登录您的专属账户

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

Saquinavir/沙奎那韦纯度/质量文件产品仅供科研

Saquinavir/沙奎那韦质控信息

Saquinavir/沙奎那韦生物活性

Saquinavir/沙奎那韦临床研究

Saquinavir/沙奎那韦参考文献

Saquinavir/沙奎那韦实验方案

Saquinavir/沙奎那韦技术信息