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货号 产品名 纯度
A184177 现货 GSK2656157

GSK2656157对蛋白激酶R(PKR)样内质网激酶(PERK)显示出选择性和ATP竞争性抑制作用,IC50为0.9 nM。

99%+
A961925 现货 NVS-CECR2-1

NVS-CECR2-1 is a potent and selective CECR2 (cat eye syndrome chromosome region, candidate 2) inhibitor with IC50 of 47 nM.

98%
A1365046 现货 AOH1160

AOH1160是一种有效的、可口服的增殖细胞核抗原 (PCNA) 抑制剂,能够干扰 DNA 复制并阻断同源重组介导的 DNA 修复,进而导致细胞周期停滞并诱导细胞凋亡AOH1160 适用于研究 DNA 损伤反应和癌症治疗中的潜在应用。

99%+
A202142 现货 LJH685

LJH685 is a potent pan-RSK inhibitor with IC50 of 6 nM, 5 nM and 4 nM for RSK1, RSK2, and RSK3, respectively.

99%+
A1351255 现货 pitstop 2

Pitstop 2 is a potent inhibitor of clathrin-independent endocytosis.

99%+
A1275491 现货 RET V804M-IN-1

RETV804M kinase inhibitor is a selective c-RET (V804M) inhibitor with IC50 value of 20nM.

98%+
A746103 现货 Oncrasin-1

Oncrasin-1 is a potent and effective anticancer inhibitor that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations and also leads to abnormal aggregation of PKCι in nucleus of sensitive cells but not in resistant cells.

99%+
A1145390 现货 Rotundifuran/蔓荆呋喃

Rotundifuran是一种从马鞭草属植物中分离的二萜类化合物,能通过抑制细胞周期进程并诱导凋亡,抑制骨髓性白血病细胞的增殖。

98%
A114431 现货 Notopterol/羌活醇

Notopterol induces apoptosis and inhibits cell cycle-specific, it's a natural product isolated and purified from the roots of Notopterygium incisum.

99%+
A1702924 现货 QN523

QN523是一种新型化学骨架的分子,在 12 种癌细胞株中显示出强大的体外细胞毒性,能够诱导细胞凋亡 (apoptosis) 和自噬 (autophagy),可用于癌症研究。

99%+
A111849 现货 Gardenin B/栀子黄素B

Gardenin B is a natural product isolated and purified from the fruits of Gardenia jasminoides Ellis.

99%+
A559999 现货 Neobavaisoflavone/新补骨脂异黄酮

Neobavaisoflavone, an isoflavone isolated from the seeds of Psoralea corylifolia, has striking anti-inflammatory and anti-cancer effects.

99%+
A225604 现货 Calcium dobesilate/羟苯磺酸钙

Calcium dobesilate effectively inhibits cell apoptosis in venous wall of primary varicose veins by regulating the expression of Bcl-2 and p53.

99%
A1441585 现货 Amifostine thiol

Amifostine thiol (WR-1065) 是细胞保护剂氨磷汀的活性代谢物。它是一种细胞保护剂,具有辐射保护能力,通过 JNK 依赖的信号通路激活 p53

98%
A204180 现货 Navitoclax

Navitoclax (ABT-263) 是一种口服有效的 Bcl-2 抑制剂,可与多种 Bcl-2 家族蛋白结合,Ki 值小于 1 nM。

99%+
A625166 现货 α-Tocopherol phosphate disodium

α-Tocopherol phosphate disodium是一种抗氧化剂,能防止长波 UVA1 诱导的细胞死亡,并清除由 UVA1 产生的活性氧 (ROS),同时能抑制内皮祖细胞凋亡,增强高糖/低氧环境下的细胞迁移能力,促进血管生成。

98%
A1176417 现货 MBM-55

MBM-55是一种高效的 NIMA 相关激酶 2 (Nek2) 抑制剂,IC50 值为 1 nM,具有抗肿瘤活性,对小鼠无明显毒性。

98%
A1745270 现货 UCB-6876

UCB-6876是一种 TNFα 抑制剂,通过与 TNFα 三聚体结合,抑制炎性反应,适用于与 TNFα 相关的自身免疫性疾病研究。

98%
A2192877 现货 CWI1-2

CWI1-2是一种 IGF2BP2 抑制剂,通过结合 IGF2BP2 并抑制其与 m6A 修饰的靶转录物相互作用,能诱导细胞凋亡与分化,展现出抗白血病的潜力。

98%
A189663 现货 Protosappanin B/原苏木素B

Protosappanin B, a natural product isolated and purified from the heart wood of Caesalpinia sappan L., significantly increases cell viability, inhibits cell apoptosis and up-regulates the expression of growth-associated protein 43, and induces the degradation of p53 protein, via activation of a MDM2-dependent ubiquitination process.

99%+
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