Carbinoxamine maleate is a blocker of histamine-H1 receptor with antihistamine and anticholinergic effects.
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HazMat fee for 500 gram (Estimated)
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USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
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Accessible (Haz class 3, 4, 5 or 8), International
Carbinoxamine maleate is a histamine-H1 receptor blocking agent with antihistamine and anticholinergic properties[3]. Carbinoxamine maleate is an antihistamine drug with mild sedation effects, which is used to treat seasonal and perennial allergic rhinitis clinically[4]. The short half-life and bitter taste of carbinoxamine maleate (CAM) lead to poor compliance by pediatric patients who are being treated for allergic rhinitis. The homemade preparations had release behaviors similar to that of the reference in vitro and achieved sustained release in vivo. The low drug loading preparation had a higher relative bioavailability of 109% owing to its faster release and better dispersibility. The suspensions based on MCRCs (microencapsulated carbinoxamine-resin complexes) could be successfully applied to treating allergic rhinitis in children[5].
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