Aclidinium bromide is a long-acting, inhaled muscarinic antagonist as a maintenance treatment for chronic obstructive pulmonary disease (COPD).

Darifenacin hydrobromide is a M3-selective antagonist with pKi of 8.9, an anticholinergic and antispasmotic agent used to treat urinary incontinence and overactive bladder syndrome.

Flavoxate HCl is a competitive AChR antagonist with IC50 of 12.2 μM, used as a muscle relaxant.

Tropicamide is a mAchR M4 antagonist, used to dilate the pupil and help with examination of the eye.

Solifenacin is a competitive antagonist of muscarinic receptors that potently blocks signaling through M1, M2, and M3 with Kis of 25, 125, and 10 nM, respectively.

Ipratropium bromide is a synthetic derivative of the alkaloid atropine anticholinergic properties with anticholinergic properties.

Otilonium bromide is an mAchR antagonist used world-wide for the treatment of irritable bowel syndrome.

Umeclidinium bromide is a long-acting mAchR antagonist with Ki values ranging in 0.05 to 0.16 nM for the cloned human M1-M5 mAChRs.

Diphenidol HCl is a non-selective mAchR antagonist and also works as a non-specific inhibitor of voltage-gated ion channels (Na+, K+, and Ca2+) in neurons.

Carβpentane citrate is a selective inhibitor of mAchR with Ki value of 76nM, also binds to serotonin 5-HT3 with Ki value of 7.9 nM and works as an agonist of the sigma-1 receptor (Ki = 10.4 nM).

Oxybutynin HCl a synthetic anticholinergic agent used for treatment of urinary incontinence and overactive bladder syndrome, with elimination half-life of ‎12.4–13.2 hours. Oxybutynin HCl is the HCl form of Oxybutynin.

Diphemanil methylsulfate can bind the muscarinic M3 receptor and decrease secretory excretion of stomach acids and saliva and sweat, as well as works as a direct smooth muscle spasmolytic activity.