PNU-120596 is a a type II positive allosteric modulator of α7 nAChRs with an EC50 of 0.2 μM.

Vinblastine Sulfate is a natural product targeting on microtubule formation, and also inhibits nAChR with IC50 value of 8.9 μM.

Benzethonium chloride是一种有效的抗微生物剂，能够抑制神经元烟碱型乙酰胆碱受体 （nAChR），应用于抗菌和抗病毒研究。

Catharanthine showed muscarinic antagonism at 10 μM and fully inhibited nicotinic receptor mediated diaphragm contractions with an IC50 of 59.6 μM. As a precursor of the anti-tumor drugs vinblastine and vincristine, it also works as an inhibitor of tubulin self-assembly into microtubules.