Qc1
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货号：A1209600
Qc 1脱氢酶 (TDH) 抑制剂，能够有效抑制代谢途径中的关键酶活性，适用于代谢性疾病的研究，特别是在代谢调节和代谢紊乱相关研究中有广泛应用。
Qc1 3D分子结构
规格
价格
会员价
库存
数量
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Qc1 纯度/质量文件 产品仅供科研
货号：A1209600
标准纯度：
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产品说明书
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Qc1 质控信息
Trilostane
✔
99+%
AGI-6780
+++
IDH2 R140Q mutant, IC50: 23 nM
99%+
Gimeracil
✔
98%
AGI-5198
++
R132H-IDH1, IC50: 70 nM
R132C-IDH1, IC50: 0.16 μM
99%+
SW033291
++++
15-PGDH, IC50: 1.5 nM
15-PGDH, Ki: 0.1 nM
99%+
Mycophenolic acid
✔
99+%
Fomepizole
✔
98%
Leflunomide
✔
98%
3-Nitropropanoic acid
✔
99%+
Isovaleramide
✔
98%
Mycophenolate Mofetil
+++
Inosine monophosphate dehydrogenase I, IC50: 39 nM
Inosine monophosphate dehydrogenase II, IC50: 27 nM
98%
MK-8245
++++
SCD1 (rat), IC50: 3 nM
SCD1 (mouse), IC50: 1 nM
99%+
Vidofludimus
++
Human DHODH, IC50: 134 nM
99%+
Emodin
✔
98%
Ivosidenib
✔
98%
NCT-501
++
98%
Gossypol
✔
99%+
Devimistat
✔
98%
Disulfiram
✔
98%+
Enasidenib
++++
98%
PluriSIn 1
✔
99%+
ML390
+
99%+
Teriflunomide
✔
99%+
Daidzin
+++
98+%
18β-Glycyrrhetinic acid
✔
99%
RRx-001
✔
95%
NCT-503
+
99%+
Vorasidenib
✔
99%+
Ammonium Glycyrrhizinate(x:1)
✔
98+%
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1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
Qc1 生物活性
描述
Qc1 is a reversible, non-competitive threonine dehydrogenase (TDH) inhibitor. Qc1 blocks the charging of tetrahydrofolate. Qc1 prevents the catabolism of threonine dehydrogenase from threonine to acetyl-CoA and glycine. Qc1 is used in the study of metabolic diseases [1] [2] [2]
Qc1 参考文献
Qc1 实验方案
计算器
摩尔计算器
总药量计算器
工作液计算器
存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
2.20mL
0.44mL
0.22mL
10.98mL
2.20mL
1.10mL
21.96mL
4.39mL
2.20mL
Qc1 技术信息
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