货号:A555383 同义名: 醋酸洗必太 / R-818;Flecainide (acetate)
Flecainide Acetate is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia and works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential.
There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type | HazMat fee for 500 gram (Estimated) |
Excepted Quantity | USD 0.00 |
Limited Quantity | USD 15-60 |
Inaccessible (Haz class 6.1), Domestic | USD 80+ |
Inaccessible (Haz class 6.1), International | USD 150+ |
Accessible (Haz class 3, 4, 5 or 8), Domestic | USD 100+ |
Accessible (Haz class 3, 4, 5 or 8), International | USD 200+ |
规格 | 价格 | 会员价 | 库存 | 数量 | |||
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快速发货 顺丰冷链运输,1-2 天到达
品质保证
技术支持
免费溶解
产品名称 | Sodium Channel ↓ ↑ | 其他靶点 | 纯度 | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tolperisone HCl | ✔ | 99% | |||||||||||||||||
Lamotrigine | ✔ | 98% | |||||||||||||||||
Vinpocetine | ✔ | 98% | |||||||||||||||||
Zonisamide | ✔ | 98% | |||||||||||||||||
Dronedarone Hydrochloride | ✔ | 95% | |||||||||||||||||
Procainamide hydrochloride | ✔ | 99% | |||||||||||||||||
Bupivacaine HCl | ✔ | 99+% | |||||||||||||||||
Benzocaine | ✔ | 98% | |||||||||||||||||
Carbamazepine |
++
Sodium channel, IC50: 131 μM |
98% | |||||||||||||||||
Ibutilide fumarate | ✔ | 99%+ | |||||||||||||||||
Dibucaine HCl | ✔ | 99+% | |||||||||||||||||
Mexiletine HCl | ✔ | 99% | |||||||||||||||||
Phenytoin | ✔ | 99+% | |||||||||||||||||
Camostat Mesylate |
+++
epithelial sodium channel (ENaC), IC50: 50 nM |
99%+ | |||||||||||||||||
Levobupivacaine | ✔ | 97+% | |||||||||||||||||
Oxcarbazepine |
+
sodium channel, IC50: 160 μM |
98% | |||||||||||||||||
Ambroxol | 98+% | ||||||||||||||||||
Primidone | ✔ | 99% | |||||||||||||||||
Propafenone | ✔ | 99% | |||||||||||||||||
A-803467 |
++++
Na(V1.8) channel, IC50: 8 nM |
99%+ | |||||||||||||||||
Rufinamide | ✔ | 99% | |||||||||||||||||
Phenytoin sodium | ✔ | 98% | |||||||||||||||||
Proparacaine Hydrochloride |
+
Voltage-gated sodium channel, ED50: 3.4 mM |
98+% | |||||||||||||||||
Riluzole | ✔ | 97% | |||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
描述 | Flecainide Acetate is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia and works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential. |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT03737929 | Atrial Fibrillation | Not Applicable | Not yet recruiting | January 2022 | France ... 展开 >> CHU Toulouse, Hôpital Rangueil Not yet recruiting Toulouse, France, 31059 Contact: Philippe Maury, MD 05 61 32 34 56 ext +33 maury.p@chu-toulouse.fr Contact: Anne Rollin, MD rollin.a@chu-toulouse.fr Principal Investigator: Philippe Maury, MD Sub-Investigator: Anne Rollin, MD Sub-Investigator: Bertrand Marcheix, MD Sub-Investigator: Etienne Grunenwald, MD 收起 << |
NCT02248753 | Atrial Fibrillation | Not Applicable | Active, not recruiting | October 2019 | Netherlands ... 展开 >> VU University Medical Center Amsterdam, Netherlands Amphia Hospital Breda, Netherlands Catharina Ziekenhuis Eindhoven, Netherlands Medisch Spectrum Twente Enschede, Netherlands University Medical Center Groningen Groningen, Netherlands Zuyderland Medical Center Heerlen, Netherlands Alrijne Hospital Leiderdorp, Netherlands Maastricht University Medical Center Maastricht, Netherlands St. Antonius Hospital Nieuwegein, Netherlands Franciscus Gasthuis Rotterdam, Netherlands Antonius Ziekenhuis Sneek, Netherlands HagaZiekenhuis The Hague, Netherlands St. Elisabeth - TweeSteden Hospital Tilburg, Netherlands Diakonessenhuis Utrecht, Netherlands VieCuri Medical Center Venlo, Netherlands 收起 << |
NCT00578617 | - | Completed | - | - | |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.11mL 0.42mL 0.21mL |
10.54mL 2.11mL 1.05mL |
21.08mL 4.22mL 2.11mL |
CAS号 | 54143-56-5 |
分子式 | C19H24F6N2O5 |
分子量 | 474.395 |
别名 | 醋酸洗必太 ;R-818;Flecainide (acetate) |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 粉末 Inert atmosphere,2-8°C |
溶解度 |
DMSO: 50 mg/mL(105.4 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO H2O: 20 mg/mL(42.16 mM),配合低频超声助溶 |
动物实验配方 |