产品说明书
Flecainide acetate
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同义名 : | 醋酸洗必太 ;R-818;Flecainide (acetate) |
| CAS号 : | 54143-56-5 | |
| 货号 : | A555383 | |
| 分子式 : | C19H24F6N2O5 | |
| 纯度 : | 98% | |
| 分子量 : | 474.395 | |
| MDL号 : | MFCD00214290 | |
| 存储条件： |
粉末 Inert atmosphere,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 50 mg/mL(105.4 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO H2O: 20 mg/mL(42.16 mM)，配合低频超声助溶 |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Flecainide Acetate is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia and works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT03737929 | Atrial Fibrillation | Not Applicable | Not yet recruiting | January 2022 | France ... 展开 >> CHU Toulouse, Hôpital Rangueil Not yet recruiting Toulouse, France, 31059 Contact: Philippe Maury, MD 05 61 32 34 56 ext +33 maury.p@chu-toulouse.fr Contact: Anne Rollin, MD rollin.a@chu-toulouse.fr Principal Investigator: Philippe Maury, MD Sub-Investigator: Anne Rollin, MD Sub-Investigator: Bertrand Marcheix, MD Sub-Investigator: Etienne Grunenwald, MD 收起 << |
| NCT02248753 | Atrial Fibrillation | Not Applicable | Active, not recruiting | October 2019 | Netherlands ... 展开 >> VU University Medical Center Amsterdam, Netherlands Amphia Hospital Breda, Netherlands Catharina Ziekenhuis Eindhoven, Netherlands Medisch Spectrum Twente Enschede, Netherlands University Medical Center Groningen Groningen, Netherlands Zuyderland Medical Center Heerlen, Netherlands Alrijne Hospital Leiderdorp, Netherlands Maastricht University Medical Center Maastricht, Netherlands St. Antonius Hospital Nieuwegein, Netherlands Franciscus Gasthuis Rotterdam, Netherlands Antonius Ziekenhuis Sneek, Netherlands HagaZiekenhuis The Hague, Netherlands St. Elisabeth - TweeSteden Hospital Tilburg, Netherlands Diakonessenhuis Utrecht, Netherlands VieCuri Medical Center Venlo, Netherlands 收起 << |
| NCT00578617 | - | Completed | - | - | |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.11mL 0.42mL 0.21mL |
10.54mL 2.11mL 1.05mL |
21.08mL 4.22mL 2.11mL |
| 参考文献 |
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