Lansoprazole sulfone (AG-1813)是一种口服活性和选择性的 H+, K+-ATPase 抑制剂，通过抑制 H+, K+-ATPase 显著刺激胃酸分泌，潜在用于治疗十二指肠溃疡、胃溃疡、胃食管反流病和佐林格-艾利森综合症。

Tegoprazan是一种钾竞争性酸阻滞剂，专门针对胃酸分泌。它通过高选择性抑制 H+/K+-ATP酶，有效缓解胃酸过多及相关胃肠道症状，对胃食管反流病和胃溃疡有潜在治疗价值。

Abeprazan (DWP14012) hydrochloride 是一种钾竞争性酸阻滞剂，通过钾竞争性离子结合可逆性抑制 H+,K+-ATPase，无需酸激活。

(S)-Lansoprazole (Levolansoprazole) 是 Lansoprazole 的一种异构体。Lansoprazole是一种质子泵抑制剂，可抑制胃酸分泌。此外，Lansoprazole (AG 1749) 还是一种中性鞘磷脂酶 (N-SMase) 抑制剂，具有外泌体抑制作用。

Pumaprazole is a reversible proton pump antagonist.

Pantoprazole sodium is an inhibitor of proton pump that can suppress function of H+/K+ ATPase. It is used for the treatment of hyperacidity.

AZD0865 inhibits gastric H+,K+-ATPase by K+-competitive binding.

Tenatoprazole is a prodrug of the proton pump inhibitor (PPI) class, which inhibits proton transport with IC50 of 3.2 μM.

SCH 28080 is an inhibitor of H+, K+-ATPase with IC50 of 20 nM.

Omeprazole sodium是一种质子泵(proton pump)抑制剂 (PPI)，在胃肠道疾病研究中具有潜力。它竞争性抑制 CYP2C19 的活性。此外，Omeprazole 还能抑制革兰氏阳性菌和革兰氏阴性菌的生长。同时，它也是中性鞘磷脂酶 (N-SMase) 的抑制剂，具有外泌体抑制的作用。

Esomeprazole Magnesium Trihydrate can inhibit the H+/K+ ATPase and reduce acid secretion of gastric parietal cells.

Rabeprazole sodium is an inhibitor of proton pump with antiulcer activities.

Lansoprazole is an inhibitor of proton-pump. It can reduce the gastric acid production of stomach.

Omeprazole sulfide is an inhibitor of proton pump, it is the metabolite of omeprazole.

Esomeprazole sodium, the sodium salt of esomeprazole which has the effect of reducing gastric acid secretion.

Omeprazole is an inhibitor of proton pump with IC50 of 1.1 μM which can be used to treat dyspepsia.

Ilaprazole inhibited TOPK activities with high affinity and selectivity.

(R)-Lansoprazole, the dextrorotatory enantiomer of lansoprazole, can irreversibly inactivate the H+/K+-stimulated ATPase pump.

Esomeprazole magnesium is a proton pump inhibitor for the treatment of gastric acid secretion.

Rabeprazole, an antiulcer drug, can irreversibly inhibit gastric H+/K+ ATPase pump with IC50 of 72 nM.