There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
Zinc Pyrithione is an antifungal and antibacterial agent by disrupting membrane transport through blocking the proton pump[1]. Zinc Pyrithione is also a copper ionophore, facilitating the transport of copper ions into cells, which is beneficial for studying cuproptosis[2].
体外研究
Zinc Pyrithione is a coordination complex where the pyrithione ligands, formally monoanions, chelate to zinc ions (Zn 2+) via oxygen and sulfur centers. In its crystalline form, it forms a centrosymmetric dimer, with each zinc ion bonded to two sulfur and three oxygen centers. In solution, these dimers can dissociate by breaking one Zn-O bond. As a dimer, Zinc Pyrithione is likely biologically active in its monomer form and is known to induce plasma membrane depolarization, with a half-maximal effective concentration (K1/2) of approximately 0.3 mM[1].
Zinc Pyrithione, at concentrations ranging from 10 nM to 10 μM over a period of 72 hours, significantly promotes cell death in AAVS1 cells[2].
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HazMat Fee +
