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Oxidopamine HCl
6-羟基多巴胺盐酸盐 /Oxidopamine HCl
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货号：A798419
同义名：
6-Hydroxydopamine hydrochloride;6-OHDA hydrochloride
Oxidopamine HCl is a neurotoxic synthetic organic compound, selectively destroys dopaminergic and noradrenergic neurons in the brain.
Oxidopamine HCl 化学结构
CAS号：28094-15-7
Oxidopamine HCl 3D分子结构
CAS号：28094-15-7
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Oxidopamine HCl 纯度/质量文件 产品仅供科研
货号：A798419
标准纯度：
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Oxidopamine HCl 质控信息
| Penfluridol |
+
Dopamine receptor, Ki: 1.6 μM
|
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98% |
| Ansofaxine HCl |
++
Dopamine receptor, IC50: 491 nM
|
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98% |
| Tetrahydroberberine,THB |
|
+
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98+% |
| Prochlorperazine Maleate |
|
✔
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95% |
| Olanzapine |
|
✔
|
|
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99+% |
| Trifluoperazine |
|
++++
Dopamine D2 receptor, IC50: 1.1 nM
|
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98% |
| Ropinirole hydrochloride |
|
++
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|
99% |
| Lurasidone |
|
++++
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|
98% |
| Levosulpiride |
|
✔
|
|
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|
99+% |
| Pridopidine |
|
✔
|
|
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|
|
95% |
| Metoclopramide |
|
✔
|
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✔
|
|
99+% |
| Molindone HCl |
|
✔
|
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98% |
| Sulpiride |
|
✔
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99+% |
| Perospirone |
|
++++
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99% |
| Perospirone HCl |
|
++++
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98+% |
| Phenothiazine |
|
✔
|
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|
|
98% |
| Pimozide |
+
Dopamine D1 receptor, Ki: 6600 nM
|
+++
Dopamine D2 receptor, Ki: 3.0 nM
|
++++
Dopamine D3 receptor, Ki: 0.83 nM
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|
|
|
|
|
98% |
| Rotundine |
++
D1 receptor, IC50: 166 nM
|
+
D2 receptor, IC50: 1.47 μM
|
+
D3 receptor, IC50: 3.25 μM
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|
|
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|
|
98% |
| Domperidone |
|
✔
|
|
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|
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|
99+% |
| ONC206 |
|
✔
|
|
|
|
|
|
|
97% |
| Pimethixene maleate |
++
Dopamine D1 Receptor, pKi: 6.37
|
+++
Dopamine D2 Receptor, pKi: 8.19
|
|
++
Dopamine D4.4 Receptor, pKi: 7.54
|
|
|
|
|
97% |
| Loxapine succinate |
++
D1 receptor (human), Ki: 26 nM
D2 receptor (Human), Ki: 62 nM
|
++
D2 receptor (bovine), Ki: 26 nM
D2 receptor (human), Ki: 24 nM
|
|
+++
D4 receptor (human), Ki: 7.5 nM
|
|
|
|
|
99% |
| Chlorprothixene |
+++
|
+++
|
+++
|
|
+++
|
|
|
|
98% |
| SCH-23390 HCl |
++++
D1 dopamine receptor, Ki: 0.2 nM
|
|
|
|
++++
D5 dopamine receptor, Ki: 0.3 nM
|
|
|
|
98% |
| MPP+ iodide |
|
|
|
|
|
✔
|
|
|
97% |
| σ1 Receptor antagonist-1 |
|
|
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|
+
|
|
|
97% |
| Benztropine mesylate |
|
|
|
|
|
++
|
|
|
98% |
| Azaperone |
|
|
|
|
|
|
✔
|
|
98% |
| Ziprasidone HCl |
|
|
|
|
|
|
✔
|
|
98+% |
| Paliperidone |
|
|
|
|
|
|
✔
|
|
98% |
| Alizapride HCl |
|
|
|
|
|
|
✔
|
|
99+% |
| Amisulpride |
|
|
|
|
|
|
✔
|
|
98% |
| Quetiapine hemifumarate |
|
|
|
|
|
|
✔
|
Adrenergic Receptor
|
98% |
| Clozapine N-oxide |
|
|
|
|
|
|
✔
|
|
99% |
|
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
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Oxidopamine HCl 生物活性
| 描述 |
Oxidopamine hydrochloride is a neurotoxic synthetic organic compound, selectively destroys dopaminergic and noradrenergic neurons in the brain. |
Oxidopamine HCl 临床研究
| NCT号 |
适应症或疾病 |
临床期 |
招募状态 |
预计完成时间 |
地点 |
|
NCT01108029
|
Parkinson's Disease
... 展开 >> Gait Disorders, Neurologic 收起 << |
Phase 4 |
Completed |
- |
France
... 展开 >> Devos
Lille, France, 59037 收起 << |
Oxidopamine HCl 参考文献
Oxidopamine HCl 实验方案
| 计算器 |
|
| 存储液制备 |
 |
1mg |
5mg |
10mg |
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1 mM
5 mM
10 mM
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4.86mL
0.97mL
0.49mL
|
24.31mL
4.86mL
2.43mL
|
48.63mL
9.73mL
4.86mL
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Oxidopamine HCl 技术信息
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