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5,7-Dimethoxyluteolin是多巴胺转运蛋白 (DAT) 的活化剂,EC50值为3.417 µM,能够用于神经系统相关研究。
Centanafadine HCl是一种双重去甲肾上腺素 (NE) 和多巴胺 (DA) 转运抑制剂,同时对 5-羟色胺转运体也有抑制作用。其对 NE、DA 和 5-HT 转运体的 IC50 值分别为 6 nM、38 nM 和 83 nM,适用于注意缺陷多动障碍 (ADHD) 及其他神经系统疾病的研究。
Vanoxerine 2HCl is a selcetive and potent Dopamine reuptake inhibitor (DRI).
Lobeline HCl is a mixed agonist–antagonist of nAchR agonist and has multiple function such as VMAT2 ligand, inhibiting the reuptake of dopamine and serotonin, antagonist at μ-opioid receptors and P-glycoprotein inhibitor.
(R)-CR8 is a cyclin dependent kinase (cdk) inhibitor with IC50 of 0.036 - 0.07 and 0.09 - 0.8 μM for cdk2 and cdk1,respectively.
Oxidopamine hydrobromide is a selective catecholaminergic neurotoxin, depletes brain catecholamine levels via uptake and accumulation by a transport mechanism specific to these neurons.
6-TAMRA has been used fluorophore for preparing bioconjugates, especially fluorescent antibody and avidin derivatives used in immunochemistry.
Diclofensine is a potent inhibitor of monoamine reuptake, blocking the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC50 values of 0.74, 2.3, and 3.7 nM, respectively.
GBR 12935 2HCl is a potent and selective dopamine reuptake inhibitor with KD of 5.5 nM in rat striatal membranes.
GBR 12935 is a potent, and selective dopamine reuptake inhibitor.
Amitifadine HCl is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).
Tags: DAT | 神经信号通路 | Neuronal Signaling | DAT 相关产品
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