Oxidopamine hydrobromide is a selective catecholaminergic neurotoxin, depletes brain catecholamine levels via uptake and accumulation by a transport mechanism specific to these neurons.

Reserpine is a naturally occuring brain-penetrant and irreversible VMAT (vesicular monoamine transporter 1 and 2) antagonist.

Haloperidol 是一种典型的抗精神病药，对 D2 多巴胺受体具有高亲和力。Haloperidol 具有抗精神病作用，主要用于精神分裂症和其他精神障碍的治疗。

MPTP hydrochloride 是可透过血脑屏障的多巴胺 (dopamine) 神经毒素，用于诱导帕金森综合症模型。MPTP hydrochloride 是 MPP+ 的前体，可以诱导细胞凋亡 (apoptosis)。

Reserpine HCl is a naturally occuring brain-penetrant and irreversible VMAT (vesicular monoamine transporter 1 and 2) antagonist.

Rotenone is a proven complex I inhibitor with IC50 value of 1.7 - 2.2 μM.

Oxidopamine HCl is a neurotoxic synthetic organic compound, selectively destroys dopaminergic and noradrenergic neurons in the brain.

Lactacystin is a potent and selective proteasome inhibitor with an IC50 of 4.8 μM for 20S proteasome found in Streptomyces. Lactacystin also inhibits the lysosomal enzyme cathepsin A.