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(-)-Isocorypalmine
四氢非洲防己胺 /(-)-Isocorypalmine
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货号：A415437
同义名：
(-)-异延胡索单酚碱
/ Tetrahydrocolumbamine;(S)-Tetrahydrocolumbamine
(-)-Isocorypalmine, a natural product isolated and purified from the tubers of Corydalis yanhusuo W. T. Wang, with significant antifungal activity, also acts as a D1 partial agonist and a D2 antagonist to produce its in vivo effects and may be a promising agent for treatment of cocaine addiction.
(-)-Isocorypalmine 化学结构
(-)-Isocorypalmine 3D分子结构
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(-)-Isocorypalmine 纯度/质量文件 产品仅供科研
货号：A415437
标准纯度：
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产品说明书
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(-)-Isocorypalmine 质控信息
Penfluridol
+
Dopamine receptor, Ki: 1.6 μM
98%
Ansofaxine HCl
++
Dopamine receptor, IC50: 491 nM
98%
Tetrahydroberberine,THB
+
98+%
Prochlorperazine Maleate
✔
95%
Olanzapine
✔
99+%
Trifluoperazine
++++
Dopamine D2 receptor, IC50: 1.1 nM
98%
Ropinirole hydrochloride
++
99%
Lurasidone
++++
98%
Levosulpiride
✔
99+%
Pridopidine
✔
95%
Metoclopramide
✔
✔
99+%
Molindone HCl
✔
98%
Sulpiride
✔
99+%
Perospirone
++++
99%
Perospirone HCl
++++
98+%
Phenothiazine
✔
98%
Pimozide
+
Dopamine D1 receptor, Ki: 6600 nM
+++
Dopamine D2 receptor, Ki: 3.0 nM
++++
Dopamine D3 receptor, Ki: 0.83 nM
98%
Rotundine
++
D1 receptor, IC50: 166 nM
+
D2 receptor, IC50: 1.47 μM
+
D3 receptor, IC50: 3.25 μM
98%
Domperidone
✔
99+%
ONC206
✔
97%
Pimethixene maleate
++
Dopamine D1 Receptor, pKi: 6.37
+++
Dopamine D2 Receptor, pKi: 8.19
++
Dopamine D4.4 Receptor, pKi: 7.54
97%
Loxapine succinate
++
D2 receptor (Human), Ki: 62 nM
D1 receptor (human), Ki: 26 nM
++
D2 receptor (bovine), Ki: 26 nM
D2 receptor (human), Ki: 24 nM
+++
D4 receptor (human), Ki: 7.5 nM
99%
Chlorprothixene
+++
+++
+++
+++
98%
SCH-23390 HCl
++++
D1 dopamine receptor, Ki: 0.2 nM
++++
D5 dopamine receptor, Ki: 0.3 nM
98%
MPP+ iodide
✔
97%
σ1 Receptor antagonist-1
+
97%
Benztropine mesylate
++
98%
Azaperone
✔
98%
Ziprasidone HCl
✔
98+%
Paliperidone
✔
98%
Alizapride HCl
✔
99+%
Amisulpride
✔
98%
Quetiapine hemifumarate
✔
Adrenergic Receptor
98%
Clozapine N-oxide
✔
99%
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1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
(-)-Isocorypalmine 生物活性
描述
(-)-Isocorypalmine, a natural product isolated and purified from the tubers of Corydalis yanhusuo W. T. Wang, with significant antifungal activity, also acts as a D1 partial agonist and a D2 antagonist to produce its in vivo effects and may be a promising agent for treatment of cocaine addiction.
(-)-Isocorypalmine 参考文献
(-)-Isocorypalmine 实验方案
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总药量计算器
工作液计算器
存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
2.93mL
0.59mL
0.29mL
14.65mL
2.93mL
1.46mL
29.29mL
5.86mL
2.93mL
(-)-Isocorypalmine 技术信息
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