N-Methylcytisine's nicotinic receptors have high affinity (KD = 50 nM)to nAChR from squid optical ganglia.

Vincamone 是vincamine和vinpocetine的代谢物，具有血管扩张作用。

Peimine can inhibit the production of inflammatory cytokines induced by LPS and block MAPK and NF-κB signaling pathways. It is purified from the bulbus of fritillaria thunbergii.

Peimisine is a steroidal alkaloid which is the major biologically active component in Bulbus Fritillariae and possess a variety of toxicological and pharmacological effects on humans.

Peiminine, a natural product isolated and purified from the bulbus of Fritillaria thunbergii Miq., is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.It induces autophagic cell death thus represses colorectal carcinoma tumor growth.

Dehydroevodiamine is an alkaloid isolated from E. rutaecarpa and possesses anti-inflammatory, antiarrhythmic, hypotensive, and anti-amnesic biological activities.

Dictamnine, a natural product isolated and purified from the root barks of Dictamnus dasycarpus Turcz., has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells, and has antimicrobial activity against bacteria and fungi.

Tetrahydroberberine is an isoquinoline alkaloid isolated and purified from the barks of Phellodendron chinense Schneid. It has micromolar affinity for dopamine D(2) (pK (i) = 6.08) and 5-HT(1A) (pK (i) = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors(5-HT(1B), 5-HT(1D), 5-HT(3), and 5-HT(4); pK (i) < 5.00).

Berbamine, a natural product isolated and purified from the roots of Cocculus orbiculatus (L.) DC., has high binding affinity toward the (GGA)8 G-quadruplex, and is a promising agent to suppress liver cancer growth by targeting CAMKII.

Groenlandicine是从黄连中分离得到的一种原小檗碱生物碱，具有中度抑制人类重组醛糖还原酶 (HRAR) 的作用，IC50值为154.2 μM，并能诱导拓扑异构酶I介导的DNA裂解。

Berberrubine, a natural product isolated and purified from the herbs of Coptis chinensis Franch. with antitumor and antidiabetic activity, dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expression of the cells stimulated with IL-1beta or TNF-alpha.

Berbamine dihydrochloride 是一种对多发性骨髓瘤具有显著疗效的NF-κB抑制剂。

Demethyleneberberine (DMB), a component of CPC, is reported to treat alcoholic liver disease as a novel natural mitochondria-targeted antioxidant.

Leonurine HCl is a major alkaloid compound extracted fromLeonurus japonicasHoutt.

Neotuberostemonine, a natural product isolated and purified from the roots of Stemona tuberosa, has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of macrophages and demonstrates antitussive properties in guinea pigs.

Aristolactam I是一种马兜铃酸I的主要代谢产物，直接作用于肾近端小管细胞，导致细胞毒性和肾损伤，其毒性效力高于AA-I，主要通过caspase-3依赖性细胞凋亡途径介导。

Crotonoside 是从中草药巴豆（Croton tiglium）中分离出的。Crotonoside 抑制 FLT3 和 HDAC3/6，在急性髓性白血病（AML）细胞中表现出选择性的抑制作用。Crotonoside 可能是 AML 研究中有前途的新先导化合物。

Aurantiamide is an orally active constituent of Portulaca oleracea L and has various biological activities, including antioxidant, antiplatelet, anti-inflammatory, and antitumor activities.

Kukoamine B is a component of Lycii Cortex, with anti-oxidant, anti-acute inflammatory and anti-diabetic properties.

N-​Feruloyloctopamine是一种抗氧化剂，能够显著抑制 Akt 和 p38 MAPK 的磷酸化，具有抗炎和抗氧化作用，适用于代谢紊乱和炎症相关疾病的研究。