Daunorubicin HCl can inhibit both DNA synthesis (Ki = 0.02 μM) and RNA synthesis.

Acelarin is a ProTide transformation and enhancement of the widely-used nucleoside analogue, gemcitabine.

Cisplatin (CDDP) 是一种抗肿瘤化疗剂，通过与 DNA 交联引起癌细胞中的 DNA 损伤。Cisplatin 可激活铁死亡 (ferroptosis) 并诱导自噬 (autophagy)。

Carboplatin (NSC 241240)通过与DNA结合，阻碍DNA合成，从而阻碍复制和转录过程，最终导致细胞死亡。Carboplatin是从顺铂（CDDP）衍生出来的，是一种有效的抗癌剂。

Oxaliplatin inhibits DNA synthesis by conforming DNA adducts.

Bendamustine is a DNA cross-linking agent.

Daptomycin is a lipopeptide antimicrobial agent with activity against Gram-positive organisms, including multi-resistant strains.

Trifluorothymidine is a derivative of thymidine that can inhibit thymidylate synthase and lead to DNA damage and apoptosis. It could be used to treat colorectal cancer.

Nedaplatin is a derivative of cisplatin and DNA damage agent.

Cidofovir is an anti-CMV drug which can suppress CMV replication by selective inhibition of viral DNA polymerase and therefore prevention of viral replication and transcription.

Robinetin, a natural product isolated and purified from the leaves of Robinia pseudacacia, has antioxidant and antiradical activities, inhibits EYPC membrane lipid peroxidation and HbA glycosylation with high efficiency.

Triglycidyl isocyanurate是一种抗血管生成和抗肿瘤活性化合物，通过激活p53抑制肿瘤细胞生长，适用于癌症研究。

Fexinidazole is a 5-nitroimidazole drug for the treatment of human sleeping sickness (human African trypanosomiasis [HAT]), caused by infection with species of the protozoan parasite Trypanosoma brucei.

Blasticidin S inhibits protein synthesis by acting on the step of peptide transfer from peptidyl-sRNA to incoming aminoacyl-sRNA.

Cytarabine是一种核苷类似物，诱导S期细胞周期停滞并抑制DNA聚合酶。它以16 nM的IC50抑制DNA合成，并对HSV具有抗病毒作用。阿糖胞苷还表现出抗正痘病毒的活性。

Metronidazole is an inhibitor of OAT3 and can inhibit the transport activity of OAT3 with IC50 and Ki of 6.51 ± 0.99 μM, 6.48 μM, respectively. It is also an antibacterial agent for anaerobic bacteria and protozoa.