Topiramate is a selective GluK1 kainate receptors (GluR5) antagonist with IC50 value of 0.46 μM which can act as a positive allosteric modulator of GABAA receptor-mediated currents, inhibit Nav channels and L-type Ca2+ channels.
Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase. Topiramate (25-100 mg/kg, i.p.) produced a dose-dependent elevation in the threshold for clonic seizures induced by infusion of ATPA, a selective agonist of GluR5 kainate receptors[3]. Topiramate modulates brain activity in the prefrontal areas involved in the modulation of the subcortical circuit mediating aggression. Topiramate at higher concentrations appeared more efficient to decrease aggression in treated mice. ACC is a key brain region in which Topiramate may exert its dose-response effects on aggressive and antisocial behaviors observed in populations with psychotic disorders[4]. Topiramate produced activation in several cortical areas and in the lateral septum of resident brain mice compared with their controls. However, Topiramate induced inhibition in the medial nucleus of the amygdala, the dorsomedial nucleus of the periaqueductal gray, and especially in the anterior hypothalamic nucleus. The dose of 0.1 mM of Topiramate appeared more efficacy to treat aggression in adult mice[5].
United States, Virginia
... 展开 >>
University of Virginia Center for Addiction Research and Education
Recruiting
Charlottesville, Virginia, United States, 22911
Contact: Mindy Borszich 888-882-2345 mcb3x@virginia.edu
Contact: Eva Jenkins-Mendoza (434)243-0562 emj9c@virginia.edu
Principal Investigator: Bankole Johnson, DSc,MD,PhD
Sub-Investigator: Nassima Ait-Daoud, MD
University of Virginia Center for Addiction Research and Education
Recruiting
Richmond, Virginia, United States, 23294
Contact: Mindy Borszich 888-882-2345 mcb3x@virginia.edu
Contact: Eva Jenkins-Mendoza (434)243-0562 emj9c@virginia.edu
Principal Investigator: Bankole Johnson, DSc,MD,PhD
Sub-Investigator: Nassima Ait-Daoud, MD 收起 <<
United States, California
... 展开 >>
VA San Diego Healthcare System, San Diego, CA
Recruiting
San Diego, California, United States, 92161
Contact: Sonya B Norman, PhD 858-552-8585 ext 5198 Sonya.Norman@va.gov
Principal Investigator: Sonya B. Norman, PhD 收起 <<
United States, Virginia
... 展开 >>
UVA CARE
Charlottesville, Virginia, United States, 22911
UVA CARE Richmond
Richmond, Virginia, United States, 23294 收起 <<
United States, California
... 展开 >>
University of California, San Diego
Active, not recruiting
La Jolla, California, United States, 92093
United States, Texas
University of Texas MD Anderson Cancer Center
Recruiting
Houston, Texas, United States, 77030
Contact: O'Neak Henigan 713-745-4472 OCHenigan@manderson.org
Principal Investigator: Paul M Cinciripini, Ph.D.
United States, Virginia
University of Virginia Center for Addiction Research & Education
Active, not recruiting
Charlottesville, Virginia, United States, 22911
University of Virginia Center for Addiction Research & Education
Active, not recruiting
Richmond, Virginia, United States, 23294 收起 <<
Canada, Ontario
... 展开 >>
MacAnxiety Research Centre
Recruiting
Hamilton, Ontario, Canada, L8S 1B7
Contact: Beth Patterson, BScN, BEd 905-921-7644 bpatter@mcmaster.ca
Principal Investigator: Michael Van Ameringen, MD, FRCPC
Sub-Investigator: Steve Collins, MBChB, FRCPC 收起 <<
United States, California
... 展开 >>
San Francisco VA Medical Center
Recruiting
San Francisco, California, United States, 94121
Principal Investigator: Steven L. Batki, MD 收起 <<
Korea, Republic of
... 展开 >>
Seoul National University Hospital
Recruiting
Seoul, Korea, Republic of
Contact: Sang kun Lee, MD,PhD sangkun2923@gmail.com
Contact: Jung-won Shin, MD limitsum@gmail.com
Principal Investigator: Sang kun Lee, MD, PhD 收起 <<
United States, Minnesota
... 展开 >>
University of Minnesota
Minneapolis, Minnesota, United States, 55455
Prism Research
Saint Paul, Minnesota, United States, 55114 收起 <<
United States, Pennsylvania
... 展开 >>
Corporal Michael J. Crescenz VA Medical Center
Recruiting
Philadelphia, Pennsylvania, United States, 19104
Contact: Timothy S Pond, MPH 215-746-1959 timpond@pennmedicine.upenn.edu
Principal Investigator: Henry Kranzler, MD
University of Pennsylvania Treatment Research Center
Recruiting
Philadelphia, Pennsylvania, United States, 19104
Contact: Timothy S. Pond, M.P.H. 215-746-1959 timpond@pennmedicine.upenn.edu
Principal Investigator: Henry R. Kranzler, M.D. 收起 <<
United States, California
... 展开 >>
Matrix Institute on Addictions
Costa Mesa, California, United States, 92627
South Bay Treatment Center
San Diego, California, United States, 92105
Torrance Site
Torrance, California, United States, 90502
United States, Hawaii
John A. Burns School of Medicine
Honolulu, Hawaii, United States, 96813
United States, Iowa
Powell Chemical Dependency Center
Des Moines, Iowa, United States, 50316
United States, Missouri
University of Missouri - Kansas City
Kansas City, Missouri, United States, 64108
United States, Utah
Salt Lake City VA Medical Center
Salt Lake City, Utah, United States, 84148
United States, Virginia
UVA CARE
Charlottesville, Virginia, United States, 22911 收起 <<
Withdrawn(The project was not ... 展开 >>announced to the field and it was not funded.) 收起 <<
November 2017
United States, Illinois
... 展开 >>
Captain James A. Lovell Federal Health Care Center, North Chicago, IL
North Chicago, Illinois, United States, 60064 收起 <<
Korea, Republic of
... 展开 >>
Busan, Korea, Republic of
Daegu, Korea, Republic of
Kwangjoo, Korea, Republic of
Kyunggi-Do, Korea, Republic of
Seoul, Korea, Republic of
Uijeongbu, Korea, Republic of 收起 <<
United States, Virginia
... 展开 >>
University of Virginia CARE Center for Addiction Research & Education
Charlottesville, Virginia, United States, 22911
UVA CARE Richmond
Richmond, Virginia, United States, 23294 收起 <<
Australia, New South Wales
... 展开 >>
Drug Health Services, Royal Prince Alfred Hospital
Recruiting
Sydney, New South Wales, Australia, 2050
Contact: Kirsten C Morley, PhD +61295153636 kirsten.morley@sydney.edu.au
Contact: Central Intake 95157611 sydneyalcoholtreatmentgroup@gmail.com
Principal Investigator: Paul Haber, MBBS 收起 <<
Japan
... 展开 >>
Bunkyo, Japan
Chitose, Japan
Hachioji, Japan
Iruma, Japan
Isehara, Japan
Iwate, Japan
Kagoshima, Japan
Kamogawa, Japan
Kitakyushu, Japan
Kobe, Japan
Kumamoto, Japan
Kyoto, Japan
Minato, Japan
Morioka, Japan
Nagoya, Japan
Nishinomiya, Japan
Sagamihara, Japan
Sapporo, Japan
Shimotsuga, Japan
Shinjuku-Ku, Japan
Shinjuku, Japan
Shizuoka, Japan
Suginami-Ku, Japan
Tokyo, Japan
Toyama, Japan
Toyonaka, Japan
Ube N/A, Japan
Ube, Japan
Yokohama, Japan
Yonago N/A, Japan 收起 <<
United States, Kentucky
... 展开 >>
University of Kentucky Medical Center
Recruiting
Lexington, Kentucky, United States, 40536
Contact: William W Stoops, Ph.D. 859-257-5388 william.stoops@uky.edu
Principal Investigator: Craig R Rush, Ph.D. 收起 <<
United States, Virginia
... 展开 >>
UVA CARE
Charlottesville, Virginia, United States, 22911
UVA CARE Richmond
Richmond, Virginia, United States, 23294 收起 <<
United States, Alabama
... 展开 >>
University of Alabama
Birmingham, Alabama, United States, 35233
United States, Florida
University of South Florida
Tampa, Florida, United States, 33612
United States, Illinois
Rush University Medical Center
Chicago, Illinois, United States, 60612
United States, North Carolina
Duke University
Durham, North Carolina, United States, 27705
United States, Oregon
Oregon Health Sciences University
Portland, Oregon, United States, 97201 收起 <<
Terminated(We terminated the s... 展开 >>tudy to run it as a sub-study of NCT02371889, which is a 13 week, placebo controlled, double-blind, trial of topiramate in heavy drinkers.) 收起 <<
United States, California
... 展开 >>
UC Davis Medical Center
Recruiting
Sacramento, California, United States, 95822
Contact: Kristin R Hoffman, MD 916-734-3261 krhoffman@ucdavis.edu
Contact: Catherine Rottkamp, MD carottkamp@ucdavis.edu
Principal Investigator: Kristin R Hoffman, MD
Sub-Investigator: Catherine Rottkamp, MD, PhD
Sub-Investigator: Sameeia Iqbal, MD 收起 <<
Terminated(We terminated the s... 展开 >>tudy to run it as a sub-study of NCT02371889, which is a 13 week, placebo controlled, double-blind, trial of topiramate in heavy drinkers.) 收起 <<
-
United States, Pennsylvania
... 展开 >>
University of Pennsylvania Center for Studies of Addiction
Philadelphia, Pennsylvania, United States, 19104 收起 <<
Japan
... 展开 >>
Chitose, Japan
Hachioji, Japan
Isehara, Japan
Iwate, Japan
Kagoshima, Japan
Kamogawa, Japan
Kitakyushu, Japan
Kobe, Japan
Kumamoto, Japan
Kyoto, Japan
Minato, Japan
Morioka, Japan
Nagoya, Japan
Nishinomiya, Japan
Sagamihara N/A, Japan
Sapporo, Japan
Shinjuku-Ku, Japan
Shizuoka, Japan
Suginami-Ku, Japan
Tokyo, Japan
Toyama, Japan
Toyonaka, Japan
Ube, Japan
Yokohama, Japan
Yonago N/A, Japan 收起 <<
United States, Rhode Island
... 展开 >>
Brown University, Center for Alcohol and Addiction Studies
Recruiting
Providence, Rhode Island, United States, 02912
Contact: Robert Jr. 401-863-6658 Robert_Miranda_Jr@Brown.EDU
Contact: Peter Monti 4018636661 Peter_Monti@brown.edu
Sub-Investigator: Peter Monti, Ph.D.
Sub-Investigator: Jennifer Tidey, Ph.D.
Sub-Investigator: Robert Swift, MD, Ph.D.
Sub-Investigator: Damaris Rohsenow, Ph.D.
Sub-Investigator: Chad Gwaltney, Ph.D.
Sub-Investigator: Alicia Justus, Ph.D. 收起 <<
United States, Pennsylvania
... 展开 >>
Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA
Recruiting
Philadelphia, Pennsylvania, United States, 19104
Contact: David W Oslin, MD 215-823-5870 Dave.Oslin@va.gov
Principal Investigator: David W. Oslin, MD 收起 <<
Canada, Ontario
... 展开 >>
Center for Addiction and Mental Health
Recruiting
Toronto, Ontario, Canada, M5T 1R8
Contact: Margaret K Hahn, MD 4165358501 ext 34368 margaret.hahn@camh.ca
Contact: Zohra A Ahsan, HBSc 4165358501 ext 34103 zohra.ahsan@camh.ca
Principal Investigator: Margaret K Hahn, MD, PhD 收起 <<
United States, Virginia
... 展开 >>
UVA Center for Leading Edge Addiction Research
Recruiting
Charlottesville, Virginia, United States, 22903
Contact: Eva Jenkins-Mendoza 434-243-0562 emj9c@virginia.edu
Contact: Tracie Kostelac (434)243-0563 tlk5d@virginia.edu 收起 <<
United States, Missouri
... 展开 >>
Saint Louis University
Recruiting
Saint Louis, Missouri, United States, 63110
Contact: Deniece D Webb, BA 314-268-7407 deniece.webb@health.slu.edu
Contact: Anthony Mikulec, MD 314-577-8884 anthony.mikulec@health.slu.edu
Principal Investigator: Anthony Mikulec, MD 收起 <<
United States, Alabama
... 展开 >>
University of Alabama Birmingham
Recruiting
Birmingham, Alabama, United States, 35233
Contact: Melanie Benge 205-975-0445 melaniebenge@uabmc.edu
Principal Investigator: Eroboghene Ubogu, MD
United States, Colorado
University of Colorado Denver
Recruiting
Aurora, Colorado, United States, 80045
Contact: Brianna Blume 303-724-6386 brianna.blume@ucdenver.edu
Principal Investigator: Dianna Quan, MD
United States, Florida
University of Miami
Recruiting
Miami, Florida, United States, 33136
Contact: Wendy Levy 305-243-6725 wel20@med.miami.edu
Principal Investigator: Mario Saporta, MD, PhD
United States, Illinois
Northwestern University
Recruiting
Chicago, Illinois, United States, 60611
Contact: Tina Ward 312-503-2128 tina.ward@northwestern.edu
Principal Investigator: Daniela Menichella, MD, PhD
United States, Kansas
University of Kansas Medical Center
Recruiting
Kansas City, Kansas, United States, 66160
Contact: Chad Parks 913-945-9938 cparks@kumc.edu
Principal Investigator: Mamatha Pasnoor, MD
United States, Massachusetts
Massachusetts General Hospital
Recruiting
Boston, Massachusetts, United States, 02114
Contact: Peter James 617-643-4218 pfjames@partners.org
Principal Investigator: Reza Seyedsadjadi, MD
United States, Missouri
Washington University School of Medicine
Recruiting
Saint Louis, Missouri, United States, 63110
Contact: Mengesha Teshome 314-747-8420 teshomem@wustl.edu
Principal Investigator: Glenn Lopate, MD
United States, New York
Columbia University Medical Center
Recruiting
New York, New York, United States, 10032
Contact: Arruem Kim 212-305-6036 ak3905@cumc.columbia.edu
Principal Investigator: Thomas Brannagan, MD
University of Rochester Medical Center
Recruiting
Rochester, New York, United States, 14642
Contact: Janet Sowden 585-275-1267 janet_sowden@urmc.rochester.edu
Principal Investigator: David Herrmann, MBBCh, MD
United States, Ohio
Ohio State University
Recruiting
Columbus, Ohio, United States, 43221
Contact: Amy Bartlett 614-366-9050 amy.bartlett@osumc.edu
Principal Investigator: Amro Stino, MD
United States, Tennessee
Vanderbilt University Medical Center
Recruiting
Nashville, Tennessee, United States, 37232
Contact: Kelly Lowen 615-936-0209 kelly.lowen@vumc.org
Principal Investigator: Amanda Peltier, MD
United States, Texas
UT Southwestern Medical Center
Not yet recruiting
Dallas, Texas, United States, 75390
Contact: Mariam Andersen 214-648-6329 mariam.andersen@utsouthwestern.edu
Principal Investigator: Lauren Phillips, MD
United States, Virginia
Eastern Virginia Medical Center
Recruiting
Norfolk, Virginia, United States, 23510
Contact: Carolina Caselllini 757-446-7976 casellcm@evms.edu
Principal Investigator: Aaron Vinik, MD,PhD
Virginia Commonwealth University
Not yet recruiting
Richmond, Virginia, United States, 23298
Contact: Gordon Smith, MD 804-828-9556 gordon.smith@vcuhealth.org
Contact: Brittney A Holmberg 804-658-6439 brittney.holmberg@vcuhealth.org
Principal Investigator: Gordon Smith, MD 收起 <<
United Kingdom
... 展开 >> Birmingham Children's Hospital
Recruiting
Birmingham, United Kingdom, B4 6NH
Contact: Shakti Agrawal, MBBS 0044 1213338149 shakti.agrawal@bch.nhs.uk
Principal Investigator: Shakti Agrawal, MBBS
Bristol Royal Hospital for Children
Recruiting
Bristol, United Kingdom, BS2 8AE
Contact: Andrew Mallick, FRCPCH
Principal Investigator: Andrew Mallick
Addenbrooke's Hospital
Recruiting
Cambridge, United Kingdom, CB2 0QQ
Contact: Alasdair Parker, MA 0044 1223 245151 alasdair.parker@addenbrookes.nhs.uk
Principal Investigator: Alasdair Parker, MA
Lancashire Teaching Hospitals NHS Foundation Trust
Recruiting
Lancashire, United Kingdom
Contact: Helen Basu Helen.Basu@lthtr.nhs.uk
Principal Investigator: Helen Basu
Leeds Teaching Hospital
Recruiting
Leeds, United Kingdom, LS1 3EX
Contact: Helen McCullagh, RCPCH 0044 113 243 2799 h.mccullagh@nhs.net
Principal Investigator: Helen McCullagh, RCPCH
Alder Hey Children's Hospital
Recruiting
Liverpool, United Kingdom, L12 2AP
Contact: Rachel Kneen, BMBS 0044 151 2525163 rachel.kneen@liverpool.ac.uk
Principal Investigator: Rachel Kneen, BMBS
Great Ormond Street Hospital
Recruiting
London, United Kingdom, WC1N 3JH
Contact: Christin Eltze, MD Res 0044 207 405 9200 ext 5438 christin.eltze@gosh.nhs.uk
Principal Investigator: Christin Eltze, MD Res
St George's University Hospitals NHS Foundation Trust
Recruiting
London, United Kingdom
Contact: Penny Fallon Penny.Fallon@stgeorges.nhs.uk
Principal Investigator: Penny Fallon
Royal Manchester Children's Hospital
Recruiting
Manchester, United Kingdom, M13 0JE
Contact: Tim Martland, RCPCH 0044 161 276 1234 timothy.martland@cmft.nhs.uk
Principal Investigator: Tim Martland, RCPCH
The Newcastle Upon Tyne Hospitals NHS Foundation Trust
Recruiting
Newcastle upon Tyne, United Kingdom
Contact: Anita Devlin Anita.Devlin@nuth.nhs.uk
Principal Investigator: Anita Devlin
Sheffield Children's NHS Foundation Trust
Recruiting
Sheffield, United Kingdom
Contact: Archana Desurkar Archana.Desurkar@sch.nhs.uk
Principal Investigator: Archana Desurkar 收起 <<
France
... 展开 >>
Not yet recruiting
Elancourt, France
Not yet recruiting
Paris, France
Not yet recruiting
Rennes, France
Netherlands
Not yet recruiting
Zwolle, Netherlands
Poland
Not yet recruiting
Kraków, Poland
Romania
Not yet recruiting
Bucuresti, Romania
Spain
Recruiting
Barcelona, Spain
Recruiting
Madrid, Spain
Recruiting
Sevilla, Spain
Sweden
Recruiting
Goteborg, Sweden 收起 <<
Brain and Central Nervous Syst... 展开 >>em Tumors 收起 <<
Phase 1
Phase 2
Completed
-
United States, Alabama
... 展开 >>
UAB Comprehensive Cancer Center
Birmingham, Alabama, United States, 35294-3410
United States, Florida
H. Lee Moffitt Cancer Center and Research Institute at University of South Florida
Tampa, Florida, United States, 33612-9497
United States, Georgia
Winship Cancer Institute of Emory University
Atlanta, Georgia, United States, 30322
United States, Maryland
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, Maryland, United States, 21231
United States, Massachusetts
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
United States, Michigan
Josephine Ford Cancer Center at Henry Ford Hospital
Detroit, Michigan, United States, 48202
United States, North Carolina
Wake Forest University Comprehensive Cancer Center
Winston-Salem, North Carolina, United States, 27157-1096
United States, Ohio
Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio, United States, 44195
United States, Pennsylvania
Abramson Cancer Center of the University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104-4283 收起 <<
Brain and Central Nervous Syst... 展开 >>em Tumors 收起 <<
Phase 2
Terminated(EORTC trail showed ... 展开 >>TMZ & RT conferred significant survivial in this population) 收起 <<
-
United States, Florida
... 展开 >>
H. Lee Moffitt Cancer Center and Research Institute
Tampa, Florida, United States, 33612-9497
United States, Georgia
Winship Cancer Institute of Emory University
Atlanta, Georgia, United States, 30322
United States, Maryland
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, Maryland, United States, 21231-2410
United States, Massachusetts
Massachusetts General Hospital Cancer Center
Boston, Massachusetts, United States, 02114-2617
United States, North Carolina
Comprehensive Cancer Center at Wake Forest University
Winston-Salem, North Carolina, United States, 27157-1030
United States, Ohio
Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio, United States, 44195
United States, Pennsylvania
Abramson Cancer Center of the University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104-4283 收起 <<
United States, Alabama
... 展开 >>
Research Site
Birmingham, Alabama, United States, 35294
United States, Connecticut
Research Site
Ridgefield, Connecticut, United States, 06877
United States, New York
Research Site
New York, New York, United States, 10025
United States, North Carolina
Research Site
Durham, North Carolina, United States, 27710
United States, Ohio
Research Site
Toledo, Ohio, United States, 43623
United States, Texas
Research Site
Austin, Texas, United States, 78731 收起 <<
Brazil
... 展开 >> Instituto de Psiquiatria do Hospital das Clínicas da Universidade de São Paulo[University of Sao Paulo General Hospital]
São Paulo, Brazil, 05403010 收起 <<
United States, Alabama
... 展开 >>
Research Site
Birmingham, Alabama, United States
United States, California
Research Site
Los Angeles, California, United States
Research Site
San Francisco, California, United States
Research Site
Spring Valley, California, United States
Research Site
Walnut Creek, California, United States
United States, Maryland
Research Site
Bethesda, Maryland, United States
United States, Texas
Research Site
Austin, Texas, United States
Research Site
San Antonio, Texas, United States
United States, Virginia
Research Site
Richmond, Virginia, United States 收起 <<
Italy
... 展开 >> Clinica Neurologica, Ospedali Riuniti
Not yet recruiting
Ancona, Italy
Contact: Leandro Provinciali, MD leandroprovinciali@gmail.com
Clinica Neurologica Amaducci, Policlinico di Bari
Not yet recruiting
Bari, Italy
Contact: Angela La Neve, MD centroepilessia@neurol.uniba.it
Principal Investigator: Angela La Neve, MD
U.S.C. Neurologia, Ospedali Riuniti
Active, not recruiting
Bergamo, Italy
Dipartimento di Scienze Neurologiche, Università degli Studi di Bologna
Recruiting
Bologna, Italy
Contact: Agostino Baruzzi, MD agostino.baruzzi@unibo.it
Contact: Barbara Mostacci, MD barbara.mostacci@unibo.it
Principal Investigator: Agostino Baruzzi, MD
Unità Operativa Complessa di Neurologia, Ospedale di Bellaria
Recruiting
Bologna, Italy
Contact: Roberto Michelucci, MD roberto.michelucci@ausl.bologna.it
Contact: Lilia Volpi, MD lilia.volpi@ausl.bologna.it
Centro Regionale dell'Epilessia, Azienda Ospedaliera Spedali Civili
Not yet recruiting
Brescia, Italy
Contact: Luisa Antonini, MD luisa.antonini@spedalicivili.brescia.it
Azienda Ospedaliera, Policlinico Universitario Mater Domini
Completed
Catanzaro, Italy, 88100
Azienda Ospedaliera ospedali Riuniti
Active, not recruiting
Foggia, Italy
Azienda Ospedaliera Universitaria Policlinico Gaetano Martino
Not yet recruiting
Messina, Italy
Contact: Edoardo Spina, MD espina@unime.it
Principal Investigator: Edoardo Spina, MD
Clinica Neurologica, Ospedale San Gerardo
Not yet recruiting
Monza, Italy
Contact: Carlo Ferrarese, MD carlo.ferrarese@unimib.it
Contact: Simone Beretta, MD simone.beretta@unimib.it
Clinica Neurologica, Azienda Ospedaliero-Universitaria Maggiore della Carità
Recruiting
Novara, Italy
Contact: Roberto Cantello, MD
Contact: Claudia Varrasi, MD claudia.varrasi@libero.it
S.C. di Neurofisiopatologia, Centro di Riferimento Regionale Umbro per l'Epilessia
Not yet recruiting
Perugia, Italy
Contact: Teresa Anna Cantisani, MD cantisani@yahoo.com
UO di Neurologia, Azienda Ospedaliero Universitaria Pisana
Active, not recruiting
Pisa, Italy
Centro Regionale Epilessie, Reggio Calabria e Università della Magna Graecia
Recruiting
Reggio Calabria, Italy
Contact: Umberto Aguglia, MD u.aguglia@tin.it
Contact: Sara Gasparini, MD
Dipartimento di Scienze Neurologiche, III Clinica Neurologica, Università "La Sapienza"
Not yet recruiting
Roma, Italy
Contact: Anna Teresa Giallonardo, MD annateresa.giallonardo@uniroma1.it
Unità Complessa di Neurologia, Ospedale SS. Giovanni e Paolo
Not yet recruiting
Venezia, Italy
Contact: Francesco Paladin, MD 收起 <<
Brazil
... 展开 >> Hospital de Clinicas de Porto Alegre
Recruiting
Porto Alegre, RS, Brazil, 90350-903
Contact: Clarissa F Paim +55 51 21018094 cfpaim@hcpa.ufrgs.br
Contact: Silza Tramontina, D.Sc. +55 51 21018094 silza.tramontina@terra.com.br
Principal Investigator: Luis A Rohde, D.Sc.
Sub-Investigator: Silza Tramontina, D.Sc.
Sub-Investigator: Cristian P Zeni, M.Sc.
Sub-Investigator: Carla R Ketzer, M.Sc.
Sub-Investigator: Gabriel F Pheula, MD
Sub-Investigator: Fernanda V Krieger, MD
Sub-Investigator: Sandra Petresco, M.Sc.
Sub-Investigator: Roberta S Coelho, B.Sc.
Sub-Investigator: Adriana F Perez, M.Sc.
Sub-Investigator: Lanuzia Brum, BA
Sub-Investigator: Ana P Guimaraes, M.Sc.
Sub-Investigator: Henrique T Ludwig 收起 <<
United States, Colorado
... 展开 >>
The Children's Hospital Colorado
Not yet recruiting
Aurora, Colorado, United States, 80045
Contact: Austin Drake 720-777-4719 austin.drake@childrenscolorado.org
Contact: Charuta Joshi, MD 1-720-777-6895 charuta.joshi@childrenscolorado.org
United States, Delaware
Nemours Alfred I. DuPont Hospital for Children
Recruiting
Wilmington, Delaware, United States, 19803
Contact: Ramany John 302-298-7521 ramany.john@nemours.org
Contact: Marisa Meyer, MD 1-302-651-4021 marisa.meyer@nemours.org
United States, Georgia
Childrens Healthcare of Atlanta
Recruiting
Atlanta, Georgia, United States, 30324
Contact: Sims Christopher 404-785-8798 christopher.sims@choa.org
Contact: Ton DeGrauw, MD 1-404-785-4446 ton.degrauw@choa.org
United States, Illinois
Ann and Robert H. Lurie Children's Hospital of Chicago
Recruiting
Chicago, Illinois, United States, 60611
Contact: Laura Fearn 312-227-6280 lfearn@luriechildrens.org
Contact: William Muller, MD 312-503-3218 wjmuller@northwestern.edu
United States, Kentucky
University of Louisville Norton Childrens Hospital
Recruiting
Louisville, Kentucky, United States, 40202
Contact: Terri Simeon 502-629-5820 theresa.simeon@louisville.edu
Contact: Arpita Lakhotia, MD 1-502-629-5820 arpita.lakhotia@louisville.edu
United States, North Carolina
University of North Carolina at Chapel Hill
Recruiting
Chapel Hill, North Carolina, United States, 27514
Contact: Shradhdha Joshi 919-966-9051 snjoshi@neurology.unc.edu
Contact: Yael Shiloh-Malawsky, MD 919-966-2922 yaelm@neurology.unc.edu
Duke University Health System
Recruiting
Durham, North Carolina, United States, 27705
Contact: Kanecia Zimmerman, MD 919-668-8651 kanecia.obie@dm.duke.edu
Contact: Harward Melissa 919-668-3910 melissa.harward@dm.duke.edu
Coastal Children's Services
Not yet recruiting
Wilmington, North Carolina, United States, 28401
Contact: Arielle Lapid 910-667-5483 arielle.lapid@ccneo.net
Contact: Sasidharan Taravath, MD 1-910-667-5165 sasi.taravath@coastalchildrensservices.net
United States, Oregon
Oregon Health and Science University
Recruiting
Portland, Oregon, United States
Contact: Kira Clark 503-418-8112 clarki@ohsu.edu
Contact: Amira Al-Uzri 1-503-494-6956 aluzria@ohsu.edu
United States, Texas
University of Texas Southwestern Medical Center Dallas
Recruiting
Dallas, Texas, United States, 75390-8589
Contact: Susan Arnold, MD 214-456-8242 susan.arnold@utsouthwestern.edu
United States, Washington
Seattle Children's Hospital
Not yet recruiting
Seattle, Washington, United States, 98105
Contact: Megan Kelton 206-987-5539 megan.kelton@seattlechildrens.org
Contact: Joseph Flynn, MD 1-206-987-2524 joseph.flynn@seattlechildrens.org 收起 <<
United States, Minnesota
... 展开 >>
Mayo Clinic in Rochester
Recruiting
Rochester, Minnesota, United States, 55905
Contact: Judith Davis 507-266-9447 RSTINDIVOBESITY@mayo.edu
Principal Investigator: Andres J Acosta 收起 <<
United States, Alabama
... 展开 >>
University of South Alabama Department of Neurology
Recruiting
Mobile, Alabama, United States, 36693
Sub-Investigator: Maher Loutfi, MD 收起 <<
United States, Florida
... 展开 >>
Clinical Pharmacology of Miami
Miami, Florida, United States, 33014-3616
Orlando Clinical Research Center
Orlando, Florida, United States, 32809-3017 收起 <<
United States, California
... 展开 >>
Research Site
San Diego, California, United States, 92130
United States, Connecticut
Research
Ridgefield, Connecticut, United States, 06877
United States, North Carolina
Research Site
Durham, North Carolina, United States, 27710
United States, Ohio
Research Site
Toledo, Ohio, United States, 43623
United States, Texas
Research Site
Austin, Texas, United States, 78731 收起 <<
United States, North Carolina
... 展开 >>
Research Site
Durham, North Carolina, United States
United States, Pennsylvania
Research Site
Philadelphia, Pennsylvania, United States 收起 <<
Terminated(Limited regulatory ... 展开 >>value to uncontrolled trials. No safety/efficacy concerns.) 收起 <<
-
United States, Alabama
... 展开 >>
Research Site
Birmingham, Alabama, United States
United States, California
Research Site
Los Angeles, California, United States
Research Site
San Francisco, California, United States
Research Site
Spring Valley, California, United States
Research Site
Walnut Creek, California, United States
United States, Maryland
Research Site
Bethesda, Maryland, United States
United States, Texas
Research Site
Austin, Texas, United States
Research Site
San Antonio, Texas, United States
United States, Virginia
Research Site
Richmond, Virginia, United States 收起 <<
United States, Alabama
... 展开 >>
Research Site
Birmingham, Alabama, United States
United States, California
Research Site
Los Angeles, California, United States
Research Site
San Francisco, California, United States
Research Site
Spring Valley, California, United States
Research Site
Walnut Creek, California, United States
United States, Maryland
Research Site
Bethesda, Maryland, United States
United States, Texas
Research Site
Austin, Texas, United States
Research Site
San Antonio, Texas, United States
United States, Virginia
Research Site
Richmond, Virginia, United States 收起 <<
United States, Louisiana
... 展开 >>
Research Facility
Baton Rouge, Louisiana, United States, 70808
Research Facility
Marrero, Louisiana, United States, 70072
United States, Ohio
Research Facility
Cincinnati, Ohio, United States, 45229
United States, South Carolina
Research Facility
Charleston, South Carolina, United States, 29403 收起 <<
United States, New York
... 展开 >>
New York University School of Medicine
Not yet recruiting
New York, New York, United States, 10016
Contact: Liliana Serrano Liliana.Serrano2@nyumc.org
Principal Investigator: mia Minen, MD 收起 <<
Brazil
... 展开 >> Hospital das Clínicas de Ribeirão Preto da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo
Recruiting
Ribeirão Preto, Sao Paulo, Brazil, 14049-900
Contact: Carolina S Vieira, MD +551636022818 carol.sales@usp.br
Contact: Leticia S Ferreira, MD +553491924258 lelezinhasanchez1@yahoo.com.br
Principal Investigator: Carolina S Vieira, MD 收起 <<
United States, California
... 展开 >>
Advanced Clinical Research Institute
Anaheim, California, United States, 92801
United States, Florida
Clinical Pharmacology of Miami
Miami, Florida, United States, 33014-3616
Orlando Clinical Research Center
Orlando, Florida, United States, 32809-3017
United States, Minnesota
DaVita Clinical Research
Minneapolis, Minnesota, United States, 55404 收起 <<
United States, Virginia
... 展开 >>
University of Virginia Center for Addiction Research and Education
Recruiting
Charlottesville, Virginia, United States, 22911
Contact: Mindy Borszich 888-882-2345 mcb3x@virginia.edu
Contact: Eva Jenkins-Mendoza (434)243-0562 emj9c@virginia.edu
Principal Investigator: Bankole Johnson, DSc, MD, PhD
Sub-Investigator: Nassima Ait-Daoud Tiouririne, MD
University of Virginia Center for Addiction Research and Education
Recruiting
Richmond, Virginia, United States, 23294
Contact: Mindy Borszich 888-882-2345 mcb3x@virginia.edu
Contact: Eva Jenkins-Mendoza (434)243-0562 emj9c@virginia.edu
Principal Investigator: Bankole Johnson, DSc, MD, PhD
Sub-Investigator: Nassima Ait-Daoud Tiouririne, MD 收起 <<
United States, Pennsylvania
... 展开 >>
Multiple Sclerosis Institute
Recruiting
Philadelphia, Pennsylvania, United States, 19146
Contact: Jeffrey I Greenstein, MD 215-985-2245
Contact: Iris J Gold, MBA 215-985-2245
Principal Investigator: Jeffrey I Greenstein, MD 收起 <<
United States, Connecticut
... 展开 >>
The New England Center for Headache, P.C.
Recruiting
Stamford, Connecticut, United States, 06902
Principal Investigator: Fred D Sheftell, M.D. 收起 <<
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