PD 151746
{[allProObj[0].p_purity_real_show]}
货号：A477369
PD151746 is a calpain inhibitor, shows a 20-fold selectivity for u-calpain (Ki = 0.26 ± 0.03 μM) over m-calpain (Ki = 5.33 ± 0.77 μM).
There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type HazMat fee for 500 gram (Estimated) Excepted Quantity USD 0.00 Limited Quantity USD 15-60 Inaccessible (Haz class 6.1), Domestic USD 80+ Inaccessible (Haz class 6.1), International USD 150+ Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+ Accessible (Haz class 3, 4, 5 or 8), International USD 200+
PD 151746 化学结构
PD 151746 3D分子结构
规格
价格
会员价
库存
数量
{[ item.pr_size ]}
{[ getRatePrice(item.pr_rmb, 1,1) ]}
{[ getRatePrice(item.pr_rmb_sale, 1,1) ]}
{[ suihuo_tips(item.pr_am, item.pr_size) ]}
{[ getRatePrice(item.pr_rmb, 1,1) ]}
{[ getRatePrice(item.pr_rmb,item.pr_rate,1) ]}
{[ suihuo_tips(item.pr_am, item.pr_size) ]}
{[ getRatePrice(item.pr_rmb, 1,1) ]}{[ suihuo_tips(item.pr_am, item.pr_size) ]}
{[ getRatePrice(item.pr_rmb_sale, 1,1) ]}
{[ getRatePrice(item.pr_rmb,item.pr_rate,item.mem_rate) ]}
{[ getRatePrice(item.pr_rmb,1,item.mem_rate) ]}
现货
咨询
-
+
PD 151746 纯度/质量文件 产品仅供科研
货号：A477369
标准纯度：
{[allProObj[0].p_purity_real_show]}
产品说明书
全球学术期刊中引用的产品
• Cell , 2024, 101755. Ambeed. A399663
]
• EMBO J. , 2024. Ambeed. A295334
]
• JMC , 2024, 67(20): 18265-18289. Ambeed. A538667 ,
A341145 ,
A117430 ,
A172297
]
• JMC , 2024. Ambeed. A210558 ,
A1518164
]
• Cell Death Discov. , 2024, 10, 436. Ambeed. A384235
]
更多 >
PD 151746 质控信息
Cysteine Protease 亚型比较
蛋白酶体 亚型比较
Z-FA-FMK
✔
99%+
Leupeptin hemisulfate
✔
97%
PMSF
✔
95%
PD 151746
+
m-calpain, IC50: 5.33 μM
μ-Calpain, IC50: 260 nM
98%
Odanacatib
++++
Cathepsin K (rabbit), IC50: 1 nM
Cathepsin K (human), IC50: 0.2 nM
99%+
E-64
+++
Cysteine protease, IC50: 9 nM
99%+
E 64c
✔
95%
E-64d
✔
99%+
MG-101
✔
98%+
Calpeptin
++
Calpain I (porcine erythrocytes), ID50: 52 nM
Calpain II (porcine kidney), ID50: 40 nM
98%+
Cathepsin inhibitor 1
+++
Cathepsin L2, pIC50: 5.5
Cathepsin L, pIC50: 7.9
98%
展开
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
Ixazomib
++++
20S proteasome, IC50: 3.4 nM
20S proteasome, Ki: 0.93 nM
99%+
Delanzomib
+++
Chymotrypsin-like proteasome, IC50: 3.8 nM
98%
Celastrol
+
20S proteasome, IC50: 2.5 μM
98%
MLN9708
+++
20S proteasome, IC50: 3.4 nM
20S proteasome, Ki: 0.93 nM
99%
Bortezomib
++++
20S proteasome, Ki: 0.6 nM
98%
Oprozomib
++
20S proteasome LMP7, IC50: 82 nM
20S proteasome β5, IC50: 36 nM
99%+
Epoxomicin
✔
99%
PI-1840
++
Chymotrypsin-like proteasome, IC50: 27 nM
98%
VR23
+++
Chymotrypsin-like proteasomes, IC50: 3 μM
Trypsin-like proteasomes, IC50: 1 nM
98%
Carfilzomib
++
98%
(R)-MG-132
+
98%
展开
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
PD 151746 生物活性
靶点
Cysteine Protease
m-calpain, IC50:5.33 μM
μ-Calpain, IC50:260 nM
描述
PD151746 is a calpain inhibitor, shows a 20-fold selectivity for u-calpain (Ki = 0.26 ± 0.03 μM) over m-calpain (Ki = 5.33 ± 0.77 μM).
PD 151746 参考文献
PD 151746 实验方案
计算器
摩尔计算器
总药量计算器
工作液计算器
存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
4.21mL
0.84mL
0.42mL
21.07mL
4.21mL
2.11mL
42.15mL
8.43mL
4.21mL
PD 151746 技术信息
搜索
HazMat Fee +
