货号:A103354 同义名: 6-姜辣素 / (S)-(+)-[6]Gingerol;[6]-Gingerol
6-Gingerol is activator transient receptor potential vanilloid receptor TRPV1 and TRP ankyrin receptor TRPA1 with EC50 of 3.3 µM and 10.4 µM. It's a natural chemical found in the rhizomes of ginger (Z. officinale).
There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type | HazMat fee for 500 gram (Estimated) |
Excepted Quantity | USD 0.00 |
Limited Quantity | USD 15-60 |
Inaccessible (Haz class 6.1), Domestic | USD 80+ |
Inaccessible (Haz class 6.1), International | USD 150+ |
Accessible (Haz class 3, 4, 5 or 8), Domestic | USD 100+ |
Accessible (Haz class 3, 4, 5 or 8), International | USD 200+ |
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快速发货 顺丰冷链运输,1-2 天到达
品质保证
技术支持
免费溶解
产品名称 | AMPK ↓ ↑ | 其他靶点 | 纯度 | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
WZ4003 |
++++
NUAK1, IC50: 20 nM NUAK2, IC50: 100 nM |
98+% | |||||||||||||||||
Dorsomorphin |
++
AMPK, Ki: 109 nM |
99% | |||||||||||||||||
HTH-01-015 |
+++
NUAK1 , IC50: 100 nM |
99%+ | |||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
描述 | 6-Gingerol, a pungent oil of fresh ginger, reduces biofilm formation and virulence by antagonistically binding to P. aeruginosa QS receptors. The height of the biofilm formed with 10 μM and 0 μM 6-gingerol was ~12 and ~25 μm, respectively. The growth of Pseudomonas aeruginosa was slightly inhibited by 0.1-100 μ m 6-gingerol[3]. Moreover,6-gingerol exhibited protective effects on apoptosis induced by Aβ1–42 in cultured PC12 cells by reducing oxidative stress and inflammatory responses, suppressing the activation of GSK-3β and enhancing the activation of Akt[4]. |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT03268655 | Colorectal Adenoma | Not Applicable | Not yet recruiting | February 2020 | United States, Minnesota ... 展开 >> Epidemiology Clinical Research Center Minneapolis, Minnesota, United States, 55415 收起 << |
NCT03089593 | Healthy Volunteers | Not Applicable | Completed | - | Brazil ... 展开 >> Hospital das Clínicas Belo Horizonte, Minas Gerais, Brazil, 30130-100 收起 << |
NCT03028454 | Muscle Soreness | Not Applicable | Completed | - | United States, Virginia ... 展开 >> Human Performance Laboratory Norfolk, Virginia, United States, 23529 收起 << |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
3.40mL 0.68mL 0.34mL |
16.98mL 3.40mL 1.70mL |
33.97mL 6.79mL 3.40mL |
CAS号 | 23513-14-6 |
分子式 | C17H26O4 |
分子量 | 294.386 |
别名 | 6-姜辣素 ;(S)-(+)-[6]Gingerol;[6]-Gingerol |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 |
溶解度 |
DMSO: 50 mg/mL(169.85 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO |
动物实验配方 |