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AN3661是一种抗疟疾的先导化合物,靶向恶性疟原虫的切割和多腺苷酸特异性因子同源物亚基 3 (PfCPSF3)。它对多种恶性疟原虫菌株均具有高效抑制作用,适用于疟疾治疗药物的研究和开发。
alpha-Lapachone, a natural product isolated and purified from the barks of Catalpa ovata, does not induce H₂O₂ formmation but shows an approximately the same trypanocidal activity of beta-lapachone.
Crotamiton is a drug that is used both as a scabicidal (for treating scabies) and as a general antipruritic.
Nimorazole is a nitroimidazole anti-infective.
Primaquine Diphosphate is an anti-malarial that prevents relapse in vivax and ovale malaria, and a potent gametocytocide in falciparum malaria.
Dixanthogen is an ectoparasiticide.
Oxantel pamoate is a widely available dewormer, potently against Trichuris muris and Hookworms.
Asparagusic acid is unique to asparagus.
Ethopabate is an arylamide veterinary drug used in the prophylaxis and treatment of coccidiosis in chickens.
Decoquinate is a coccidiostat used in veterinary medicine.
Dinotefuran is the third generation of neonicotinoid group,which works through inhibiting nAchRs.
NSC 5844 is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic properties.
Moxidectin is an anthelmintic drug which kills parasitic worms (helminths), and is used for the prevention and control of heartworm and intestinal worms.
Toltrazuril is an antiprotozoal agent used in Coccidia parasites infection.
2-Methyl-3,5-Dinitrobenzamide is a fodder additive for poultry, used to prevent coccidiosis infections.
Antimycobacterial agent-4是一种 2-氨基-4-(2-吡啶基) 噻唑衍生物,具有抗结核活性,针对 H37Rv 菌株显示出抗微生物作用,但对哺乳动物细胞系具有一定毒性。
(R)-Praziquantel-d11是 (R)-Praziquantel 的氘代物,(R)-Praziquantel 是 Praziquantel 的活性对映体,作为人 5-HT2B 受体的部分激动剂,并用作驱虫药和抗血吸虫剂。
8-Deoxygartanin是从山竹果中提取的 prenylated xanthone,具有选择性抑制 BChE 的作用,IC50 为 11.8 μM,并表现出抗疟活性和抑制 NF-κB 活化的能力。
SCYX-7158 is an effective, safe and orally active treatment for human african trypanosomiasis (HAT). In the T. b. brucei S427 strain, the MIC value for SCYX-7158 is 0.6 µg/mL.
Tioxazafen是一种二取代恶二唑,作为广谱杀线虫剂,用于保护玉米、大豆和棉花等作物免受线虫侵害,具有良好的农业应用前景。
Tags: Antiparasitic | 抗感染 | Anti-infection | Antiparasitic 相关产品
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