生物活性 | |||
---|---|---|---|
描述 | 6-Gingerol, a pungent oil of fresh ginger, reduces biofilm formation and virulence by antagonistically binding to P. aeruginosa QS receptors. The height of the biofilm formed with 10 μM and 0 μM 6-gingerol was ~12 and ~25 μm, respectively. The growth of Pseudomonas aeruginosa was slightly inhibited by 0.1-100 μ m 6-gingerol[3]. Moreover,6-gingerol exhibited protective effects on apoptosis induced by Aβ1–42 in cultured PC12 cells by reducing oxidative stress and inflammatory responses, suppressing the activation of GSK-3β and enhancing the activation of Akt[4]. |
临床研究 | |||||
---|---|---|---|---|---|
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT03268655 | Colorectal Adenoma | Not Applicable | Not yet recruiting | February 2020 | United States, Minnesota ... 展开 >> Epidemiology Clinical Research Center Minneapolis, Minnesota, United States, 55415 收起 << |
NCT03089593 | Healthy Volunteers | Not Applicable | Completed | - | Brazil ... 展开 >> Hospital das Clínicas Belo Horizonte, Minas Gerais, Brazil, 30130-100 收起 << |
NCT03028454 | Muscle Soreness | Not Applicable | Completed | - | United States, Virginia ... 展开 >> Human Performance Laboratory Norfolk, Virginia, United States, 23529 收起 << |
实验方案 | |||
---|---|---|---|
1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
3.40mL 0.68mL 0.34mL |
16.98mL 3.40mL 1.70mL |
33.97mL 6.79mL 3.40mL |
参考文献 |
---|