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1,4-O-Diferuloylsecoisolariciresinol {[allProObj[0].p_purity_real_show]}

货号：A928818

9,9'-Di-O-(E)-feruloylsecoisolariciresinol is a natural product isolated and purified from the herb of Betula ermanii, has significant cytotoxic activity against the DU145, LNCaP, and A549 cell lines, and is an inhibitor of mTOR signaling, have strong anticancer activity.

1,4-O-Diferuloylsecoisolariciresinol 化学结构
CAS号：56973-66-1

1,4-O-Diferuloylsecoisolariciresinol 3D分子结构
CAS号：56973-66-1

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1,4-O-Diferuloylsecoisolariciresinol 纯度/质量文件产品仅供科研

货号：A928818 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

全球学术期刊中引用的产品: • Cell Host Microbe, 2024. Ambeed. [ A163338 ]; • Cancer Res., 2024. Ambeed. [ A295334 ]; • J. Pharm. Investig., 2024. Ambeed. [ A221527 , A691302 , A272538 , A187261 ]; • J. Fungi, 2024, 10(11): 751. Ambeed. [ A796919 ]; • JBC, 2024, 107935. Ambeed. [ A194396 ]; 更多 >

mTOR 亚型比较

产品名称	mTOR ↓ ↑	mTORC1 ↓ ↑	mTORC2 ↓ ↑	其他靶点	纯度
AZD-8055	++++ mTOR (truncated), IC50: 0.13 nM mTOR (full length), IC50: 0.8 nM				99%+
Gedatolisib	++++ mTOR, IC50: 1.6 nM				98%
GSK1059615	++ mTOR, IC50: 12 nM				98%
Vistusertib	+++ mTOR, IC50: 2.8 nM				99%+
Torin 1	+++ mTOR, IC50: 4.32 nM	+++ mTORC1, IC50: 2 nM	++ mTORC2, IC50: 10 nM	DNA-PK	99%+
Dactolisib	+++ mTOR (p70S6K), IC50: 6 nM				98+%
PI-103	+ mTOR, IC50: 30 nM				99%+
WAY-600	++ mTOR, IC50: 9 nM				99%
Voxtalisib	+ mTOR, IC50: 157 nM				99%+
PF-04691502	++ mTOR, Ki: 16 nM				98+%
Onatasertib	++ mTOR, IC50: 16 nM			DNA-PK	99%+
Chrysophanol	✔			EGFR	98%
Samotolisib	✔			DNA-PK	99%+
Torkinib	+++ mTOR, IC50: 8 nM			DNA-PK,PDGFR	99%+
Everolimus					99%+
WYE-354	+++ mTOR, IC50: 5 nM				98%
Tacrolimus	✔				98%
PP121	++ mTOR, IC50: 13 nM			VEGFR,PDGFR	99%+
Torin 2	++++ mTOR, IC50: 0.25 nM			DNA-PK	99%+
Rapamycin	++++ mTOR, IC50: ~0.1 nM				98%
GDC-0349	+++ mTOR, Ki: 3.8 nM				98%
XL388	++ mTOR, IC50: 9.9 nM	+++ mTORC1, IC50: 8 nM	+ mTORC2, IC50: 166 nM		99%+
WYE-687	+++ mTOR, IC50: 7 nM				98+%
Apitolisib	+ mTOR, Ki app: 17 nM				98%+
WYE-132	++++ mTOR, IC50: 0.19 nM				99%+
Sapanisertib	++++ mTOR, Ki: 1.4 nM				99%+
BGT226 maleate	✔				99%+
ETP-46464	++++ mTOR, IC50: 0.6 nM			DNA-PK	98%
PI3K-IN-1	+ mTOR, IC50: 157 nM				98+%
Zotarolimus	+++ FKBP-12, IC50: 2.8 nM				99+%
OSI-027	+++ mTOR, IC50: 4 nM	+ mTORC1, IC50: 22 nM	+ mTORC2, IC50: 65 nM		99%+
Ridaforolimus	++++ mTOR, IC50: 0.2 nM				99%+
Temsirolimus	+ mTOR, IC50: 1.76 μM				99%
CZ415	++ mTOR, pIC50: 8.07				99%+
SF2523	+ mTOR, IC50: 280 nM			DNA-PK	99%+
KU-0063794		++ mTORC1, IC50: ~10 nM	++ mTORC2, IC50: ~10 nM		99%+
Omipalisib		++++ mTORC1, Ki: 0.18 nM	++++ mTORC2, Ki: 0.3 nM		99%+
Palomid 529		✔			99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

1,4-O-Diferuloylsecoisolariciresinol 生物活性

描述	9,9'-Di-O-(E)-feruloylsecoisolariciresinol is a natural product isolated and purified from the herb of Betula ermanii, has significant cytotoxic activity against the DU145, LNCaP, and A549 cell lines, and is an inhibitor of mTOR signaling, have strong anticancer activity.

1,4-O-Diferuloylsecoisolariciresinol 参考文献

[1]Lin RJ, Cheng MJ, et al. Phytochemical Investigation and Cytotoxic Evaluation of Components of Leaves and Stems of Machilus zuihoensis var. mushaensis. Chemistry of Natural Compounds. 2014;50(6):978-81.

1,4-O-Diferuloylsecoisolariciresinol 实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

1.40mL

0.28mL

0.14mL

7.00mL

1.40mL

0.70mL

13.99mL

2.80mL

1.40mL

1,4-O-Diferuloylsecoisolariciresinol 技术信息

CAS号	56973-66-1
分子式	C₄₀H₄₂O₁₂
分子量	714.754

别名
运输	蓝冰

存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末

溶解度

动物实验配方

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1,4-O-Diferuloylsecoisolariciresinol 纯度/质量文件 产品仅供科研

全球学术期刊中引用的产品

1,4-O-Diferuloylsecoisolariciresinol 质控信息

1,4-O-Diferuloylsecoisolariciresinol 生物活性

1,4-O-Diferuloylsecoisolariciresinol 参考文献

1,4-O-Diferuloylsecoisolariciresinol 实验方案

1,4-O-Diferuloylsecoisolariciresinol 技术信息

最近浏览的产品

大规格询价

摩尔计算器

靶点

总药量计算器

工作液计算器

细胞研究

临床研究

确认信息

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1,4-O-Diferuloylsecoisolariciresinol 纯度/质量文件产品仅供科研