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Nonivamide, an analog of capsaicin, is agonist of transient receptor potential vanilloid type 1 (TRPV1). It can be extracted from the fruits of Capsicum annuum L..
Serotonin HCl is an endogenous 5-HT receptor agonist.
ATP disodium salt hydrate (Adenosine 5'-triphosphate disodium salt hydrate) 是能量储存和代谢的核心成分,为泵提供代谢能量并作为细胞中的辅酶。它是免疫和炎症中的重要内源性信号分子。
Oxaliplatin inhibits DNA synthesis by conforming DNA adducts.
Ethynyl Estradiol is an estrogen used in formulations of combined contraceptive pills.
Chloroquine 是一种抗疟药物,同时也是自噬抑制剂,对自噬过程具有抑制作用,IC50 值为 2.1 μM。Chloroquine 具有抗疟、抗炎和抗肿瘤作用,可用于自噬研究和抗疟疾治疗。
Alprostadil is an analog of prostaglandin which is prostaglandin E1 agonist with vasodilatory properties and can be used to treat erectile dysfunction.
Paclitaxel 是一种天然抗肿瘤药物,能稳定微管蛋白 (tubulin) 的聚合,导致有丝分裂停滞和诱导细胞凋亡 (apoptosis),最终导致细胞死亡。Paclitaxel 还可诱导细胞自噬 (autophagy)。
Reserpine is a naturally occuring brain-penetrant and irreversible VMAT (vesicular monoamine transporter 1 and 2) antagonist.
Histamine phosphate can dilate arteries and capillaries mediated by H1- and H2-receptors.
Histamine 2HCl is the 2HCl form of histamine which is an organic nitrogen compound that articipates in immune responses and inflammatory reactions and also can be used as neurotransmitters
Chloroquine phosphate是一种广泛用于治疗疟疾和类风湿性关节炎的抗疟药和抗炎剂。它是一种自噬和 Toll 样受体 (TLR) 抑制剂,在体外控制 SARS-CoV-2 (COVID-19) 感染的效果非常显著 (EC50 = 1.13 μM)。
Prostaglandin E2 is a natural prostaglandin and acts as a vasodilator by activating the prostaglandin E2 receptor.
Tags: 疼痛和瘙痒模型 | Pain and Pruritus Model | 动物造模剂 | Animal Modeling Agent | 疼痛和瘙痒模型 相关产品
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