RHC 80267 is a diacylglycerol (DAG) lipase inhibitor and an important second messenger in signal transduction pathways.

KML29 is a highly selective and potent MAGL inhibitor with IC50s for 15, 43, and 5.9 nM in mouse, rat, and human brain proteomes, respectively.

AA38-3是一种丝氨酸水解酶 (SH) 抑制剂，能够有效抑制ABHD6、ABHD11和FAAH三种SHs。这使得它在脂质代谢和神经保护研究中具有应用前景。

Pristimerin是一种高效的单甘油脂肪酶 (MGL) 可逆抑制剂，IC50 为 93 nM。

Lalistat 2是一种多种脂肪酶的抑制剂，尤其是溶酶体酸性脂肪酶（LAL）。它常用于研究 LAL 的细胞特异性功能及 LAL 缺乏症，并在脂质代谢相关研究中发挥作用。

JW 642 is a potent inhibitor of monoacylglycerol lipase (MAGL) that displays IC50 values of 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively.

JJKK 048 is a potent and selective monoacylglycerol lipase (MAGL) inhibitor with IC50 of 0.4 nM.

ABX-1431 works as both a cannabinoid receptor agonist and a MAGL inhibitor.

Ibrolipim is a Lipoprotein lipase activator.

JZL 184 is a potent and selective inhibitor of MAGL with IC50 of 8 nM and 4 μM for inhibition of MAGL and FAAH in mouse brain membranes respectively.

H-Phe(4-Ac)-OH是一种含有酮基团的氨基酸，常用于突变 Z 结构域蛋白的研究，具有多种生物化学应用。

JNJ-42226314是一种竞争性、高度选择性和可逆的非共价单酰甘油脂肪酶 MAGL 抑制剂，能够剂量依赖性增强主要内源性大麻素 2-花生四烯酰甘油 (2-AG)，在神经性和炎性疼痛模型中表现出抗伤害作用。

DB2313 is a first-in-class potent small-molecule inhibitor of PU.1. DB2313 disrupts the interaction of PU.1 with target gene promoters and leads to down-regulation of canonical PU.1 transcriptional targets.

LCL521 2HCl, an inhibitor of acid ceramidase, shows anticancer actions of lysosomally targeted.

Atglistatin is a potent, selective and competitive ATGL with IC50 value of 0.7 μM.

XEN445 is a potent and selective endothelial lipase inhibitor with IC50 of 0.237 μM.

Orlistat is an approved reversible general lipase inhibitor with IC50 of 122 ng/mL, used to treat obesity.

Cetilistat is a novel pancreatic lipase used to treat obesity.

MAGL-IN-5是一种非选择性的脂肪酶抑制剂，能够抑制单酰基甘油脂肪酶 (MAGL)、激素敏感脂肪酶 (HSL) 和脂肪酸酰胺水解酶 (FAAH)，IC₅₀ 值分别为 144、90 和 14 nM，常用于脂质代谢和神经退行性疾病研究。