Celecoxib is a selective COX-2 inhibitor with IC50 of 40 nM.

Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively, and is used for pain relief, fever reduction and for reducing swelling.

Rofecoxib is a potent inhibitor of the COX2-dependent production of PGE2 in human osteosarcoma cells with IC50 of 26±10 nM and Chinese hamster ovary cells expressing human COX-2 with IC50 of 18±7 nM.

Diclofenac sodium is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively, used as a nonsteroidal anti-inflammatory drug (NSAID) to relieve pain and reduce swelling in flammation.

Lumiracoxib is a COX2 selective inhibitor and a non-steroidal anti-inflammatory drug (NSAID), which inhibits COX2 with IC50 and Ki values of 0.14 μM and 0.06 μM and inhibits COX1 with Ki of 3 μM.

Lornoxicam is a COX inhibitor with IC50 of 5 nM and 8 nM for COX1 and 2 respectively. It's a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of various types of pain.

Naproxen is a COX inhibitor for COX1/2 with IC50 of 8.7 and 5.2 μM, respectively.

Ketorolac, a non-selective COX inhibitor with IC50s of 1.23 μM and 3.50 μM for COX1 and COX2, is a non-steroidal anti-inflammatory drug.

Valdecoxib is a potent COX inhbitor that selectively inhibitors COX-2 with IC50 of 5 nM.

Tolfenamic acid is a selective COX2 inhibitor with IC50 of 13.49 μM, it's a non-steroidal anti-inflammatory drugs (NSAIDs).

Amfenac Sodium Monohydrate is a non-steroidal analgesic anti-inflammatory drug with acetic acid moiety. The IC50 values for COX1 and COX2 is 250 nM and 150 nM, respectively.

Nimesulide is a COX2 selective inhibitor with IC50 of 26 μM.

NS-398是一种非甾体抗炎剂，具有镇痛和退热作用。它选择性抑制前列腺素G/H合酶2/环氧合酶2（COX-2）的活性，IC50值为3.8 μM，而对COX-1在100 μM时没有影响。

Meclofenamate Sodium is a dual COX-1/COX-2 inhibitor with IC50 of 40 nM and 50 nM, respectively, used in the treatment of joint, muscular pain, arthritis and dysmenorrhea.

Carprofen reduces inflammation by inhibition of COX-2 with IC50 of 30 nM, does not interfere with COX-1 activity.

Asaronaldehyde is a COX-2 inhibitor, exhibiting 17-fold selectivity over COX-1, it's a natural product isolated and purified from the rhizoma of Acorus tatarinowii Schott.

Niflumic acid, a Ca2+-activated Cl- channel blocker, is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.

Etoricoxib is a selective COX2 inhibitor with IC50 of 1.1 ± 0.1 μM and 116 ± 8 μM for COX1.

Parecoxib is a potent and selective COX2 inhibitor.

Rutaecarpine, a COX-2 inhibitor, is an indolopyridoquinazolinone alkaloid isolated from Evodia rutaecarpa and related herbs.