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AM580 is the stable retinobenzoic derivative that acts as an agonist of RARα.
D4476 is a potent, selective, and cell-permeant CK1 (casein kinase 1) inhibitor with IC50 of 200 nM and 300 nM in a cell-free assay for CK1 from Schizosaccharomyces pombe and CK1δ, respectively. Also acts as an ALK5 inhibitor with IC50 of 500 nM.
BIO is an inhibitor of GSK-3 and CDK1–cyclinB complex. The IC50s of GSK-3αβ, CDK1, CDK5 are 5 nM, 320 nM and 83 nM, respectively.
StemRegenin 1 是一种有效的芳香烃受体 (AhR) 拮抗剂,IC50 为 127 nM。
Flurbiprofen is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity.
Bay-K-8644 (R)-(+)- is a calcium channel inhibitor. Bay-K-8644 (R)-(+)- inhibits Ba2+ currents (IBa) (IC50=975 nM).
TTNPB is an agonist of RAR and can inhibit binding of [3H]tRA with RARα (IC50 = 5.1 nM), RARβ (IC50 = 4.5 nM), and RARγ (IC50 = 9.3 nM).
PluriSln 1 is an inhibitor of cell pluripotency and stearoyl-coA desaturase (SCD1) that can induce ER stress and apoptosis in hPSCs.
NU7026 is a potent and selective inhibitor of DNA-PK with IC50 of 0.23 μM.
Kenpaullone is an ATP-competitive inhibitor of CDK1/cyclin B (IC50 = 0.4 µM), CDK2/cyclin A (IC50 = 0.68 µM), CDK5/p25 (IC50 = 0.85 µM), lymphocyte kinase (IC50 = 0.47 µM) , and GSK-3β (C50 = 0.23 μM).
Delphinidin chloride is an anthocyanidin isolated and purified from the fruits of Vaccinium myrtillus which serves as the precursor of certain anthocyanins that provide the blue-red colors of flowers, fruits, and red wine.
NU7441 is a potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits PI3K with IC50 of 5 μM in cell-free assays.
BSI-201 is a PARP1 inhibitor with demonstrated effectiveness in triple-negative breast cancer (TNBC).
Laduviglusib (CHIR-99021)是一种有效、选择性且具有口服活性的 GSK-3α/β 抑制剂,可用作细胞疗法中的辅助试剂。
ISX-9 is a small molecule inducer of adult neural stem cell differentiation.
Nicotinamide can act as an inhibitor of sirtuins and it is the active component of NAD and NADP.
OAC1是一种Oct-4激活剂,用于增强和加速诱导性多能干细胞(iPSC)的重编程。此外,OAC1 增加了 Oct4-Nanog-Sox2 三联体和 TET1 的转录。
KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, and with less inhibition of PI3Kγ with IC50 of 0.59 μM.
Tags: 诱导多能干细胞 | Induced Pluripotent Stem Cell | 干细胞诱导 | Stem Cell Induction | 诱导多能干细胞 相关产品
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