WNK463 is a potant With-No-Lysine (WNK) kinase inhibitor with IC50s of 5/1/6/9 nM for WNK1/2/3/4.

SPHINX31 is a potent and selective inhibitor of serine/arginine-rich protein kinase 1 (SRPK1), with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 is a potential topical therapeutic for neovascular eye disease[1].

RKI-1447 is a potent small molecule inhibitor of ROCK1 and ROCK2, with IC50 of 14.5 nM and 6.2 nM, respectively, and has anti-invasive and antitumor activities.

ML281 是一种强效、选择性的喹喔啉基 STK33 抑制剂，IC50 值为 14 nM。

Nek2/Hec1-IN-2 是 Nek2/Hec1 的抑制剂，能够抑制癌细胞增殖，IC50 值大于 25 μM。

ILK-IN-3 is an integrin linked kinase inhibitor.

GSK8612是一种高度选择性和高效的Tank结合激酶-1（TBK1）抑制剂，对重组TBK1的pIC50为6.8。

SRPIN340 is an inhibitor of serine/arginine-rich protein kinase SRPK1 with IC50 of 0.89 μM.

Netarsudil Mesylate是一种 ROCK 激酶和去甲肾上腺素转运体的双重抑制剂，适用于眼科疾病的研究，尤其是在降低眼内压及治疗青光眼方面具有显著的作用。

ZT-12-037-01 是一种选择性丝氨酸/苏氨酸激酶 STK19 的抑制剂，与 STK19 蛋白具有高亲和力相互作用，抑制 NRAS 驱动的黑素细胞恶性转化。ZT-12-037-01 是 ATP 竞争性抑制剂，可以抑制 NRAS 的磷酸化，IC50 为 24 nM。

CMPD1 is a selective inhibitor of non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation with apparent Ki (Kiapp) of 330 nM.

Midostaurin (PKC412; CGP 41251) 是一种口服活性、可逆的多靶点蛋白激酶抑制剂，抑制PKCα/β/γ、Syk、Flk-1、Akt、PKA、c-Kit、c-Fgr、c-Src、FLT3、PDGFRβ和VEGFR1/2的IC50值范围为22到500 nM。它还上调内皮一氧化氮合酶（eNOS）基因表达，并表现出强大的抗癌作用。

Enzastaurin is a potent PKCβ selective inhibitor with IC50 of 6 nM, 6- to 20-fold selectivity against PKCα, PKCγ and PKCε.

Zoledronic acid is an activator of protein kinase C with apoptotic effects on multiple myeloma cell lines.

4μ8C（IRE1抑制剂III）是一种靶向IRE1α的小分子抑制剂。

ILK-IN-2 is a ILK inhibitor.

Staurosporine is a prototypical potent ATP-competitive multikinase inhibitor with IC50 of 0.7, 7, 8.5, 6, 20 nM for PKC, PKA,PKG, p60v-src tyrosine protein kinase, CaM kinase II, respectively.

Go6983 is a pan-PKC inhibitor against for PKCα, PKCβ, PKCγ and PKCδ with IC50 of 7 nM, 7 nM, 6 nM and 10 nM, respectively and less potent to PKCζ and inactive to PKCμ.

GSK269962A is a potent ROCK inhibitor (IC50 values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively), and displays greater than 30-fold selectivity for ROCK against a panel of serine/threonine kinases.

GSK429286A selectively inhibits ROCK1 and ROCK2 with the IC50 value of 14 nM and 63 nM, respectively.