货号:A789113
同义名:
2-氨基-4-巯基丁酸
/ NSC 206252
H-DL-HoCys-OH是一种神经毒素,能够影响犬尿酸的产生,进而影响认知功能和脑白质结构。它在研究神经系统疾病及相关代谢失调中具有应用前景。
There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type | HazMat fee for 500 gram (Estimated) |
Excepted Quantity | USD 0.00 |
Limited Quantity | USD 15-60 |
Inaccessible (Haz class 6.1), Domestic | USD 80+ |
Inaccessible (Haz class 6.1), International | USD 150+ |
Accessible (Haz class 3, 4, 5 or 8), Domestic | USD 100+ |
Accessible (Haz class 3, 4, 5 or 8), International | USD 200+ |
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产品名称 | mTOR ↓ ↑ | mTORC1 ↓ ↑ | mTORC2 ↓ ↑ | 其他靶点 | 纯度 | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AZD-8055 |
++++
mTOR (full length), IC50: 0.8 nM mTOR (truncated), IC50: 0.13 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Gedatolisib |
++++
mTOR, IC50: 1.6 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
GSK1059615 |
++
mTOR, IC50: 12 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Vistusertib |
+++
mTOR, IC50: 2.8 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Torin 1 |
+++
mTOR, IC50: 4.32 nM |
+++
mTORC1, IC50: 2 nM |
++
mTORC2, IC50: 10 nM |
DNA-PK | {[allProObj[0].p_purity_real_show]} | ||||||||||||||
Dactolisib |
+++
mTOR (p70S6K), IC50: 6 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
PI-103 |
+
mTOR, IC50: 30 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
WAY-600 |
++
mTOR, IC50: 9 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Voxtalisib |
+
mTOR, IC50: 157 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
PF-04691502 |
++
mTOR, Ki: 16 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Onatasertib |
++
mTOR, IC50: 16 nM |
DNA-PK | {[allProObj[0].p_purity_real_show]} | ||||||||||||||||
Chrysophanol | ✔ | EGFR | {[allProObj[0].p_purity_real_show]} | ||||||||||||||||
Samotolisib | ✔ | DNA-PK | {[allProObj[0].p_purity_real_show]} | ||||||||||||||||
Torkinib |
+++
mTOR, IC50: 8 nM |
PDGFR,DNA-PK | {[allProObj[0].p_purity_real_show]} | ||||||||||||||||
Everolimus | {[allProObj[0].p_purity_real_show]} | ||||||||||||||||||
WYE-354 |
+++
mTOR, IC50: 5 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Tacrolimus | ✔ | {[allProObj[0].p_purity_real_show]} | |||||||||||||||||
PP121 |
++
mTOR, IC50: 13 nM |
PDGFR,VEGFR | {[allProObj[0].p_purity_real_show]} | ||||||||||||||||
Torin 2 |
++++
mTOR, IC50: 0.25 nM |
DNA-PK | {[allProObj[0].p_purity_real_show]} | ||||||||||||||||
Rapamycin |
++++
mTOR, IC50: ~0.1 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
GDC-0349 |
+++
mTOR, Ki: 3.8 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
XL388 |
++
mTOR, IC50: 9.9 nM |
+++
mTORC1, IC50: 8 nM |
+
mTORC2, IC50: 166 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||
WYE-687 |
+++
mTOR, IC50: 7 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Apitolisib |
+
mTOR, Ki app: 17 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
WYE-132 |
++++
mTOR, IC50: 0.19 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Sapanisertib |
++++
mTOR, Ki: 1.4 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
BGT226 maleate | ✔ | {[allProObj[0].p_purity_real_show]} | |||||||||||||||||
ETP-46464 |
++++
mTOR, IC50: 0.6 nM |
DNA-PK | {[allProObj[0].p_purity_real_show]} | ||||||||||||||||
PI3K-IN-1 |
+
mTOR, IC50: 157 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Zotarolimus |
+++
FKBP-12, IC50: 2.8 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
OSI-027 |
+++
mTOR, IC50: 4 nM |
+
mTORC1, IC50: 22 nM |
+
mTORC2, IC50: 65 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||
Ridaforolimus |
++++
mTOR, IC50: 0.2 nM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
Temsirolimus |
+
mTOR, IC50: 1.76 μM |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
CZ415 |
++
mTOR, pIC50: 8.07 |
{[allProObj[0].p_purity_real_show]} | |||||||||||||||||
SF2523 |
+
mTOR, IC50: 280 nM |
DNA-PK | {[allProObj[0].p_purity_real_show]} | ||||||||||||||||
KU-0063794 |
++
mTORC1, IC50: ~10 nM |
++
mTORC2, IC50: ~10 nM |
{[allProObj[0].p_purity_real_show]} | ||||||||||||||||
Omipalisib |
++++
mTORC1, Ki: 0.18 nM |
++++
mTORC2, Ki: 0.3 nM |
{[allProObj[0].p_purity_real_show]} | ||||||||||||||||
Palomid 529 | ✔ | {[allProObj[0].p_purity_real_show]} | |||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
计算器 | ||||
存储液制备 | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
7.40mL 1.48mL 0.74mL |
36.99mL 7.40mL 3.70mL |
73.97mL 14.79mL 7.40mL |
CAS号 | 454-29-5 |
分子式 | C4H9NO2S |
分子量 | 135.185 |
别名 | 2-氨基-4-巯基丁酸 ;NSC 206252 |
运输 | 蓝冰 |
存储条件 |
粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C 液体 -20°C:3-6个月-80°C:12个月 |
溶解度 |
H2O: 40 mg/mL(295.89 mM),配合低频超声助溶 |
动物实验配方 |