CK1-IN-1
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货号：A1002890
同义名：
PUN51207;Compound 1C
CK1-IN-1 is a casein kinase 1 (CK1) inhibitor extracted from patent WO2015119579A1, compound 1c, has IC50s of 15 nM, 16 nM, 73 nM for CK1δ, and CK1ε, p38σ MAPK, respectively[1].
CK1-IN-1 化学结构
CK1-IN-1 3D分子结构
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CK1-IN-1 纯度/质量文件 产品仅供科研
货号：A1002890
标准纯度：
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产品说明书
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CK1-IN-1 质控信息
PF-670462 2HCl
++++
CK1ε, IC50: 90 nM
CK1δ, IC50: 13 nM
99%+
D4476
++
CK1 from Schizosaccharomyces pombe, IC50: 200 nM
CK1δ, IC50: 300 nM
98%
SR-3029
+++
CK1ε, IC50: 260 nM
CK1δ, IC50: 44 nM
99%+
IWP-2
+++
Wnt
98%
LY364947
++
98%
TA-01
++++
CK1ε, IC50: 6.4 nM
CK1δ, IC50: 6.8 nM
p38 MAPK
99%+
IC261
+
98%
PF-4800567
+++
casein kinase 1 epsilon, IC50: 32 nM
casein kinase 1 delta, IC50: 711 nM
99%+
CK1-IN-1
++++
CK1ε, IC50: 16 nM
CK1δ, IC50: 15 nM
98%
Longdaysin
+
CKIα, IC50: 5.6 μM
CKIδ, IC50: 8.8 μM
99%+
Silmitasertib
++++
99%+
Ellagic acid (hydrate)
+++
PKA
95+%
DMAT
+++
98%
Hematein
++
98+%
Silmitasertib sodium salt
++++
CK2α', IC50: 1 nM
CK2α, IC50: 1 nM
99%+
LY294002
+++
99%+
A-3 HCl
+
++
MLCK,PKA,PKC
98+%
TBB
+
++
98%
TTP 22
++
98%+
DRB
✔
99%+
BioE-1115
+
99%+
(E/Z)-GO289
++++
99%+
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1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
CK1-IN-1 生物活性
靶点
CK1
CK1ε, IC50:16 nM
CK1δ, IC50:15 nM
描述
PUN51207 is a CK1 inhibitor with IC50 values of 15nM and 16nM for CK1δ and CK1ε, respectively, as well as exhibits inhibitory effect on p38α MAPK with IC50 value of 73nM.
CK1-IN-1 参考文献
CK1-IN-1 实验方案
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摩尔计算器
总药量计算器
工作液计算器
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1mg
5mg
10mg
1 mM
5 mM
10 mM
2.61mL
0.52mL
0.26mL
13.04mL
2.61mL
1.30mL
26.08mL
5.22mL
2.61mL
CK1-IN-1 技术信息
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