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Borneol {[allProObj[0].p_purity_real_show]}

货号:A182769 同义名: D-Borneol;(+)-Borneol

(+)-Borneol is an optical isomer of Borneol. Borneol is a component of some aromatic plant essential oils.

HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Borneol 化学结构 CAS号:464-43-7
Borneol 化学结构
CAS号:464-43-7
Borneol 3D分子结构
CAS号:464-43-7
Borneol 化学结构 CAS号:464-43-7
Borneol 3D分子结构 CAS号:464-43-7
规格 价格 会员价 库存 数量
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Borneol 纯度/质量文件 产品仅供科研

货号:A182769 标准纯度: {[allProObj[0].p_purity_real_show]}
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Niflumic Acid 98%
Ginkgolide A ++

GABA receptor, Ki: 14.5 μM

98%
Valproic acid sodium HDAC,Autophagy 97%
Flumazenil 95%
Bemegride 98%
Bicuculline +++

GABAA receptor, IC50: 2 μM

98+%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。

Borneol 生物活性

描述 (+)-Borneol, a bicyclic monoterpene found in many plants, has many biological activities. In vitro studies, (+)-borneol could improve cell cytotoxicity induced by β-amyloid in human neuroblastoma cells through decreasing reactive oxygen species generation and increasing B-cell lymphoma 2 (Bcl-2) expression. Besides this, it was found that (+)-borneol could depress p-glycoprotein on brain microvascular endothelial cells via medicating the NF-κB pathway. In vivo studies, (+)-borneol could contribute to the improvement of fear and anxiety in rats possibly by modulation of the GABAergic neurotransmission. In addition, (+)-borneol has the ability of strengthening the efficacy of edaravone against DSS-induced colitis in rats.

Borneol 动物研究

Dose Mice: 125 mg/kg - 500 mg/kg[5] (p.o.); 15 μg - 60 μg[5] (i.t.); 200 mg/kg - 600 mg/kg[6] (i.g.)
Administration p.o., i.t., i.g.

Borneol 参考文献

[1]Cao B, Ni HY, et al. (+)-Borneol suppresses conditioned fear recall and anxiety-like behaviors in mice. Biochem Biophys Res Commun. 2018;495(2):1588-1593.

[2]Hur J, Pak SC, et al. Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells. Pharm Biol. 2013;51(1):30-5.

[3]Fan X, Chai L, et al. Borneol Depresses P-Glycoprotein Function by a NF-κB Signaling Mediated Mechanism in a Blood Brain Barrier in Vitro Model. Int J Mol Sci. 2015;16(11):27576-88.

[4]Zhang X, Xu F, et al. (+)-Borneol improves the efficacy of edaravone against DSS-induced colitis by promoting M2 macrophages polarization via JAK2-STAT3 signaling pathway. Int Immunopharmacol. 2017.

Borneol 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

6.48mL

1.30mL

0.65mL

32.41mL

6.48mL

3.24mL

64.83mL

12.97mL

6.48mL

Borneol 技术信息

CAS号464-43-7
分子式C10H18O
分子量 154.249
别名 D-Borneol;(+)-Borneol;(+)-endo-Borneol;(1R)-(+)-Borneol
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Sealed in dry,2-8°C

溶解度
动物实验配方
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