货号:A182769 同义名: D-Borneol;(+)-Borneol
(+)-Borneol is an optical isomer of Borneol. Borneol is a component of some aromatic plant essential oils.
There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type | HazMat fee for 500 gram (Estimated) |
Excepted Quantity | USD 0.00 |
Limited Quantity | USD 15-60 |
Inaccessible (Haz class 6.1), Domestic | USD 80+ |
Inaccessible (Haz class 6.1), International | USD 150+ |
Accessible (Haz class 3, 4, 5 or 8), Domestic | USD 100+ |
Accessible (Haz class 3, 4, 5 or 8), International | USD 200+ |
规格 | 价格 | 会员价 | 库存 | 数量 | |||
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快速发货 顺丰冷链运输,1-2 天到达
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产品名称 | GABA receptor ↓ ↑ | GABAA receptor ↓ ↑ | 其他靶点 | 纯度 | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Niflumic Acid | ✔ | 98% | |||||||||||||||||
Ginkgolide A |
++
GABA receptor, Ki: 14.5 μM |
98% | |||||||||||||||||
Valproic acid sodium | ✔ | HDAC,Autophagy | 97% | ||||||||||||||||
Flumazenil | ✔ | 95% | |||||||||||||||||
Bemegride | ✔ | 98% | |||||||||||||||||
Bicuculline |
+++
GABAA receptor, IC50: 2 μM |
98+% | |||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
描述 | (+)-Borneol, a bicyclic monoterpene found in many plants, has many biological activities. In vitro studies, (+)-borneol could improve cell cytotoxicity induced by β-amyloid in human neuroblastoma cells through decreasing reactive oxygen species generation and increasing B-cell lymphoma 2 (Bcl-2) expression. Besides this, it was found that (+)-borneol could depress p-glycoprotein on brain microvascular endothelial cells via medicating the NF-κB pathway. In vivo studies, (+)-borneol could contribute to the improvement of fear and anxiety in rats possibly by modulation of the GABAergic neurotransmission. In addition, (+)-borneol has the ability of strengthening the efficacy of edaravone against DSS-induced colitis in rats. |
Dose | Mice: 125 mg/kg - 500 mg/kg[5] (p.o.); 15 μg - 60 μg[5] (i.t.); 200 mg/kg - 600 mg/kg[6] (i.g.) |
Administration | p.o., i.t., i.g. |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
6.48mL 1.30mL 0.65mL |
32.41mL 6.48mL 3.24mL |
64.83mL 12.97mL 6.48mL |
CAS号 | 464-43-7 |
分子式 | C10H18O |
分子量 | 154.249 |
别名 | D-Borneol;(+)-Borneol;(+)-endo-Borneol;(1R)-(+)-Borneol |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 粉末 Sealed in dry,2-8°C |
溶解度 | |
动物实验配方 |