山姜素 /Alpinetin
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货号：A265742
Alpinetin can act as an inhibitor of UCK2 and shows antioxidant, anticancer and antithrombotic properties. Alpinetin is mainly found in ginger plants.
Alpinetin 化学结构
Alpinetin 3D分子结构
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Alpinetin 纯度/质量文件 产品仅供科研
货号：A265742
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Alpinetin 质控信息
Alpinetin 生物活性
描述
Alpinetin, a flavonoid compound extracted from the seeds of Alpinia katsumadai Hayata, acted as a potential AhR activator. in vivo , alpinetin (7.5, 15, 30 mg/kg) dose-dependently reduced the myeloperoxidase (MPO) activity. Moreover, alpinetin (15, 30 mg/kg) significantly up-regulated levels of IL-10 and Foxp3 in colons of colitis mice. in vitro , alpinetin (30 μM) could activate AhR in EL-4 cells[3] [4]
Alpinetin 参考文献
[1] Jiang Z, Sang H, et al. Alpinetin enhances cholesterol efflux and inhibits lipid accumulation in oxidized low-density lipoprotein-loaded human macrophages. Biotechnol Appl Biochem. 2015 Nov-Dec;62(6):840-7.
[2] Guan S, Fang B, et al. Immunosuppressive activity of alpinetin on activation and cytokines secretion of murine T lymphocytes. Immunopharmacol Immunotoxicol. 2014 Aug;36(4):290-6.
[3] Lv Q, Shi C, Qiao S, et al. Alpinetin exerts anti-colitis efficacy by activating AhR, regulating miR-302/DNMT-1/CREB signals, and therefore promoting Treg differentiation. Cell Death Dis. 2018;9(9):890. Published 2018 Aug 30.
[4] Wu L, Yang W, Zhang SN, Lu JB. Alpinetin inhibits lung cancer progression and elevates sensitization drug-resistant lung cancer cells to cis-diammined dichloridoplatium. Drug Des Devel Ther. 2015;9:6119-6127. Published 2015 Nov 16.
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Alpinetin 实验方案
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存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
3.70mL
0.74mL
0.37mL
18.50mL
3.70mL
1.85mL
37.00mL
7.40mL
3.70mL
Alpinetin 技术信息
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